Difference between revisions of "Ferruginous body"
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'''Ferruginous body''' is a histopathologic finding in [[lung pathology]] that strongly | [[Image:Ferruginous bodies - BAL - r3 -- very high mag.jpg|right|thumb|300px|Ferruginous body in a BAL. (WC)]] | ||
'''Ferruginous body''' is a histopathologic finding in [[lung pathology]] that strongly suggests exposure to asbestos. | |||
==General== | ==General== | ||
| Line 7: | Line 8: | ||
Conditions associated with asbestos exposure (mnemonic ''PALM''):<ref name=Ref_PCPBoD8_375>{{Ref PCPBoD8|375}}</ref> | Conditions associated with asbestos exposure (mnemonic ''PALM''):<ref name=Ref_PCPBoD8_375>{{Ref PCPBoD8|375}}</ref> | ||
*[[Pleural plaques]]. | *[[Pleural plaques]]. | ||
*Asbestosis. | *[[Asbestosis]]. | ||
*[[Lung carcinoma]]. | *[[Lung carcinoma]]. | ||
*[[Malignant mesothelioma]]. | *[[Malignant mesothelioma]]. | ||
| Line 13: | Line 14: | ||
==Microscopic== | ==Microscopic== | ||
Features: | Features: | ||
*Segmented twirling baton with long slender fibre within. | *Segmented twirling baton-like structure (approximately 3-5 micrometres x 20-80 micrometres) with long slender fibre within. | ||
*Black/brown crystal-like appearance. | *Black/brown crystal-like appearance. | ||
DDx: | DDx: | ||
*Dirt - especially on H&E. | *Dirt - especially on H&E. | ||
===Images=== | |||
<gallery> | |||
Image:Ferruginous_body.jpg | Ferruginous bodies. (WC) | |||
</gallery> | |||
====Cytology==== | |||
<gallery> | |||
Image: Ferruginous bodies - BAL - r1 -- high mag.jpg | FB - high mag. (WC) | |||
Image: Ferruginous bodies - BAL - r1 -- very high mag.jpg | FB - very high mag. (WC) | |||
Image: Ferruginous bodies - BAL - r2 -- very high mag.jpg | FB - very high mag. (WC) | |||
Image: Ferruginous bodies - BAL - r3 -- high mag.jpg | FB - high mag. (WC) | |||
Image: Ferruginous bodies - BAL - r3 -- very high mag.jpg | FB - very high mag. (WC) | |||
Image:Carcinoma asbestos body lung.jpg | Ferruginous body in carcinoma - cytology. (WC/Alex Brollo) | |||
</gallery> | |||
==Stains== | ==Stains== | ||
*Prussian blue +ve. | *[[Prussian blue stain]] +ve. | ||
==Sign out== | |||
<pre> | |||
Comment: | |||
No cell block is available for further work-up, e.g. iron staining. | |||
The findings herein should be correlated with imaging and the clinical history. | |||
Ferruginous bodies are associated asbestos exposure. | |||
</pre> | |||
==See also== | ==See also== | ||
Latest revision as of 17:46, 20 May 2018
Ferruginous body is a histopathologic finding in lung pathology that strongly suggests exposure to asbestos.
General
- Uncommon finding.
- Strongly suggestive of asbestos exposure.
Conditions associated with asbestos exposure (mnemonic PALM):[1]
Microscopic
Features:
- Segmented twirling baton-like structure (approximately 3-5 micrometres x 20-80 micrometres) with long slender fibre within.
- Black/brown crystal-like appearance.
DDx:
- Dirt - especially on H&E.
Images
Ferruginous bodies. (WC)
Cytology
FB - high mag. (WC)
FB - very high mag. (WC)
FB - very high mag. (WC)
FB - high mag. (WC)
FB - very high mag. (WC)
Ferruginous body in carcinoma - cytology. (WC/Alex Brollo)
Stains
- Prussian blue stain +ve.
Sign out
Comment: No cell block is available for further work-up, e.g. iron staining. The findings herein should be correlated with imaging and the clinical history. Ferruginous bodies are associated asbestos exposure.
See also
References
- ↑ Mitchell, Richard; Kumar, Vinay; Fausto, Nelson; Abbas, Abul K.; Aster, Jon (2011). Pocket Companion to Robbins & Cotran Pathologic Basis of Disease (8th ed.). Elsevier Saunders. pp. 375. ISBN 978-1416054542.