Difference between revisions of "Sarcomatoid carcinoma of the lung"

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'''Sarcomatoid carcinoma of the lung''' is a rare epithelial derived malignant with [[sarcoma]]-like morphologic features.<ref name=pmid20073605>{{Cite journal  | last1 = Franks | first1 = TJ. | last2 = Galvin | first2 = JR. | title = Sarcomatoid carcinoma of the lung: histologic criteria and common lesions in the differential diagnosis. | journal = Arch Pathol Lab Med | volume = 134 | issue = 1 | pages = 49-54 | month = Jan | year = 2010 | doi = 10.1043/2008-0547-RAR.1 | PMID = 20073605 }}</ref>  
'''Sarcomatoid carcinoma of the lung''' is a rare epithelial derived lung malignancy that has morphologic features suggestive of a malignant mesenchymal tumour ([[sarcoma]]).<ref name=pmid20073605>{{Cite journal  | last1 = Franks | first1 = TJ. | last2 = Galvin | first2 = JR. | title = Sarcomatoid carcinoma of the lung: histologic criteria and common lesions in the differential diagnosis. | journal = Arch Pathol Lab Med | volume = 134 | issue = 1 | pages = 49-54 | month = Jan | year = 2010 | doi = 10.1043/2008-0547-RAR.1 | PMID = 20073605 }}</ref>   It is a '''sarcoma-like lung carcinoma'''.


==General==
*Rare.<ref name=pmid20073605/>
*Associated with [[smoking]].<ref name=pmid20073605/>
==Gross==
*Mass lesion - typically upper lobe and peripheral location.<ref name=pmid20073605/>
==Microsopic==
Subclassified as:<ref name=pmid20073605/>
*Pleomorphic carcinoma.
*Spindle cell carcinoma.
*Giant cell carcinoma.
*Carcinosarcoma.
*[[Pulmonary blastoma]].
DDx:
*[[Poorly differentiated lung carcinoma]] (non-small cell lung carcinoma).
*Primary lung sarcoma.
*Metastatic disease:
**[[Carcinosarcoma]].
**Poorly differentiated carcinoma.
**[[Sarcoma]].
===Images===
<gallery>
Image: Adenosquamous carcinoma with sarcomatoid change of lung -- intermed mag.jpg | ASC with SC - intermed. mag. (WC)
Image: Adenosquamous carcinoma with sarcomatoid change of lung -- high mag.jpg | ASC with SC - high mag. (WC)
Image: Adenosquamous carcinoma with sarcomatoid change of lung - adeno -- very high mag.jpg | ASC with SC - very high mag. (WC)
Image: Adenosquamous carcinoma with sarcomatoid change of lung - squamous -- very high mag.jpg | ASC with SC - very high mag. (WC)
</gallery>
<gallery>
Image: Adenocarcinoma with sarcomatoid change - lung -- intermed mag.jpg | AdCa and SC (in ASC) - intermed. mag. (WC)
Image: Adenocarcinoma with sarcomatoid change - lung -- high mag.jpg | AdCa and SC (in ASC) - intermed. mag. (WC)
Image: Adenocarcinoma with sarcomatoid change - lung -- very high mag.jpg | AdCa and SC (in ASC) - very high mag. (WC)
</gallery>


==See also==
==See also==

Latest revision as of 05:49, 29 December 2015

Sarcomatoid carcinoma of the lung is a rare epithelial derived lung malignancy that has morphologic features suggestive of a malignant mesenchymal tumour (sarcoma).[1] It is a sarcoma-like lung carcinoma.

General

Gross

  • Mass lesion - typically upper lobe and peripheral location.[1]

Microsopic

Subclassified as:[1]

  • Pleomorphic carcinoma.
  • Spindle cell carcinoma.
  • Giant cell carcinoma.
  • Carcinosarcoma.
  • Pulmonary blastoma.

DDx:

Images

  • ASC with SC - intermed. mag. (WC)

  • ASC with SC - high mag. (WC)

  • ASC with SC - very high mag. (WC)

  • ASC with SC - very high mag. (WC)

  • AdCa and SC (in ASC) - intermed. mag. (WC)

  • AdCa and SC (in ASC) - intermed. mag. (WC)

  • AdCa and SC (in ASC) - very high mag. (WC)

See also

References

  1. ↑ 1.0 1.1 1.2 1.3 1.4 Franks, TJ.; Galvin, JR. (Jan 2010). "Sarcomatoid carcinoma of the lung: histologic criteria and common lesions in the differential diagnosis.". Arch Pathol Lab Med 134 (1): 49-54. doi:10.1043/2008-0547-RAR.1. PMID 20073605.
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