Difference between revisions of "Hidradenitis suppurativa"
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'''Hidradenitis suppurativa''', also known as '''acne inversa''',<ref name=pmid24767187>{{cite journal |author=Dessinioti C, Katsambas A, Antoniou C |title=Hidradenitis suppurrativa (acne inversa) as a systemic disease |journal=Clin. Dermatol. |volume=32 |issue=3 |pages=397–408 |year=2014 |pmid=24767187 |doi=10.1016/j.clindermatol.2013.11.006 |url=}}</ref> is a benign [[skin]] condition. | '''Hidradenitis suppurativa''' (abbreviated '''HS'''), also known as '''acne inversa''',<ref name=pmid24767187>{{cite journal |author=Dessinioti C, Katsambas A, Antoniou C |title=Hidradenitis suppurrativa (acne inversa) as a systemic disease |journal=Clin. Dermatol. |volume=32 |issue=3 |pages=397–408 |year=2014 |pmid=24767187 |doi=10.1016/j.clindermatol.2013.11.006 |url=}}</ref> is a benign [[skin]] condition. | ||
==General== | ==General== | ||
*Uncommon - <1% of population.<ref name=pmid24812161>{{cite journal |author=McMillan K |title=Hidradenitis Suppurativa: Number of Diagnosed Patients, Demographic Characteristics, and Treatment Patterns in the United States |journal=Am. J. Epidemiol. |volume= |issue= |pages= |year=2014 |month=May |pmid=24812161 |doi=10.1093/aje/kwu078 |url=}}</ref> | *Uncommon - <1% of population.<ref name=pmid24812161>{{cite journal |author=McMillan K |title=Hidradenitis Suppurativa: Number of Diagnosed Patients, Demographic Characteristics, and Treatment Patterns in the United States |journal=Am. J. Epidemiol. |volume= |issue= |pages= |year=2014 |month=May |pmid=24812161 |doi=10.1093/aje/kwu078 |url=}}</ref> | ||
*Onset usually after puberty and before 40 years old.<ref name=pmid1916780>{{cite journal |author=Radcliffe KW |title=Hidradenitis suppurativa |journal=Genitourin Med |volume=67 |issue=1 |pages=58 |year=1991 |month=February |pmid=1916780 |pmc=1194617 |doi= |url=}}</ref> | |||
May be associated with:<ref name=pmid24767187/> | May be associated with:<ref name=pmid24767187/> | ||
*[[Crohn's disease]]. | *[[Crohn's disease]]. | ||
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*Location - classically intertriginous areas.<ref>{{cite journal |author=Scheinfeld N |title=Hidradenitis suppurativa: A practical review of possible medical treatments based on over 350 hidradenitis patients |journal=Dermatol. Online J. |volume=19 |issue=4 |pages=1 |year=2013 |pmid=24021361 |doi= |url=}}</ref> | *Location - classically intertriginous areas.<ref>{{cite journal |author=Scheinfeld N |title=Hidradenitis suppurativa: A practical review of possible medical treatments based on over 350 hidradenitis patients |journal=Dermatol. Online J. |volume=19 |issue=4 |pages=1 |year=2013 |pmid=24021361 |doi= |url=}}</ref> | ||
**Axilla, buttocks, groin, inner thighs, breast (inframammary fold). | **Axilla, buttocks, groin, inner thighs, breast (inframammary fold). | ||
==Microscopic== | |||
Features:<ref name=pmid1916780/> | |||
*Apocrine ducts plugged by keratin and dilated - '''key feature'''. | |||
*+/-Bacteria and inflammation in the congested ducts. | |||
*+/-Fibrosis (late). | |||
DDx: | |||
*[[Pilonidal disease]]. | |||
===Images=== | |||
*[http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632012000200018#fig5 HS (scielo.br)]. | |||
==Sign out== | |||
<pre> | |||
SKIN AND SUBCUTANEOUS TISSUE, RIGHT AXILLA, EXCISION: | |||
- DILATED APOCRINE DUCTS AND A FIBROTIC DERMIS WITH MILD CHRONIC | |||
PERIVASCULAR INFLAMMATION, SEE COMMENT. | |||
- EPIDERMAL INCLUSION CYSTS. | |||
COMMENT: | |||
The findings are compatible with hidradenitis suppurativa. | |||
</pre> | |||
==See also== | ==See also== | ||
Latest revision as of 16:32, 27 April 2016
Hidradenitis suppurativa (abbreviated HS), also known as acne inversa,[1] is a benign skin condition.
General
May be associated with:[1]
Gross
Features:
- Location - classically intertriginous areas.[4]
- Axilla, buttocks, groin, inner thighs, breast (inframammary fold).
Microscopic
Features:[3]
- Apocrine ducts plugged by keratin and dilated - key feature.
- +/-Bacteria and inflammation in the congested ducts.
- +/-Fibrosis (late).
DDx:
Images
Sign out
SKIN AND SUBCUTANEOUS TISSUE, RIGHT AXILLA, EXCISION: - DILATED APOCRINE DUCTS AND A FIBROTIC DERMIS WITH MILD CHRONIC PERIVASCULAR INFLAMMATION, SEE COMMENT. - EPIDERMAL INCLUSION CYSTS. COMMENT: The findings are compatible with hidradenitis suppurativa.
See also
- Skin.
References
- ↑ 1.0 1.1 Dessinioti C, Katsambas A, Antoniou C (2014). "Hidradenitis suppurrativa (acne inversa) as a systemic disease". Clin. Dermatol. 32 (3): 397–408. doi:10.1016/j.clindermatol.2013.11.006. PMID 24767187.
- ↑ McMillan K (May 2014). "Hidradenitis Suppurativa: Number of Diagnosed Patients, Demographic Characteristics, and Treatment Patterns in the United States". Am. J. Epidemiol.. doi:10.1093/aje/kwu078. PMID 24812161.
- ↑ 3.0 3.1 Radcliffe KW (February 1991). "Hidradenitis suppurativa". Genitourin Med 67 (1): 58. PMC 1194617. PMID 1916780. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1194617/.
- ↑ Scheinfeld N (2013). "Hidradenitis suppurativa: A practical review of possible medical treatments based on over 350 hidradenitis patients". Dermatol. Online J. 19 (4): 1. PMID 24021361.