Difference between revisions of "Case 3"
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Intermediate magnification. H&E stain.
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===Clinical history=== | ===Clinical history=== | ||
45 year old woman, renal mass. | |||
===Primary image=== | ===Primary image=== | ||
| Line 19: | Line 19: | ||
{{hidden|More history|<center>Sister had a renal tumour. Biopsy diagnosis was ''[[clear cell renal cell carcinoma]]''.</center>}} | {{hidden|More history|<center>Sister had a renal tumour. Biopsy diagnosis was ''[[clear cell renal cell carcinoma]]''.</center>}} | ||
====Ask a friend==== | ====Ask a friend==== | ||
{{hidden|Ask a friend|<center> | {{hidden|Ask a friend|<center>There is one immunostain I think would be really useful here. If I am right, this case may have the [[chromosomal translocation]] seen in [[alveolar soft part sarcoma]].</center>}} | ||
====Stains==== | ====Stains==== | ||
| Line 62: | Line 62: | ||
| warthinstarry= | | warthinstarry= | ||
}} | }} | ||
====IHC==== | ====IHC==== | ||
{{Case IHC | {{Case IHC | ||
| blank=Dr | | blank= Dr Torres would ask why! | ||
| ae1ae3= | | ae1ae3= | ||
| a1at= | | a1at= | ||
| Line 71: | Line 70: | ||
| afp= | | afp= | ||
| alk1= | | alk1= | ||
| amacr= | |||
| b2microgl= | | b2microgl= | ||
| b723= | | b723= | ||
| bcatenin= | |||
| bcl2= | | bcl2= | ||
| bcl6= | | bcl6= | ||
| Line 80: | Line 81: | ||
| calponin= | | calponin= | ||
| calretinin= | | calretinin= | ||
| cd10= '''POSITIVE''' | | cd10= '''POSITIVE''' | ||
| cd117= | | cd117= | ||
| cd15= | | cd15= | ||
| Line 98: | Line 99: | ||
| cd56= | | cd56= | ||
| cd68= | | cd68= | ||
| cd7= | | cd7= | ||
| cd79a= | | cd79a= | ||
| cd8= | | cd8= | ||
| Line 107: | Line 108: | ||
| ck20= | | ck20= | ||
| ck34be12= | | ck34be12= | ||
| ck7= | | ck7= '''NEGATIVE''' | ||
| cmv= | | cmv= | ||
| cmyc= | | cmyc= | ||
| Line 145: | Line 146: | ||
| lh= | | lh= | ||
| lysozyme= | | lysozyme= | ||
| melanina= '''NEGATIVE''' | | melanina= '''NEGATIVE''' | ||
| mitf= | |||
| myleoperox= | | myleoperox= | ||
| myod1= | | myod1= | ||
| Line 151: | Line 153: | ||
| myog= | | myog= | ||
| nse= | | nse= | ||
| p16= | |||
| p53= | | p53= | ||
| p63= | | p63= | ||
| Line 160: | Line 163: | ||
| psa= | | psa= | ||
| s100= | | s100= | ||
| sma= | | sma= | ||
| somatsat= | | somatsat= | ||
| synapto= | | synapto= | ||
| tdt= | | tdt= | ||
| tfe3= '''POSITIVE''' | |||
| thyrogl= | | thyrogl= | ||
| toxopl= | | toxopl= | ||
| Line 171: | Line 175: | ||
| uchl1= | | uchl1= | ||
| ulexeurope= | | ulexeurope= | ||
| vim= '''POSITIVE''' | | vim= '''POSITIVE''' | ||
| vip= | | vip= | ||
| vzv= | | vzv= | ||
| wt1= | |||
}} | |||
====Chromosomal translocations==== | |||
{{Case Translocations | |||
| blank=Dr Torres would ask why! | |||
| t1_13= | |||
| t11_14= | |||
| t11_22dsrct= | |||
| t11_22ews= | |||
| t12_15= | |||
| t12_16afh= | |||
| t12_16liposar= | |||
| t12_22= | |||
| t14_18= | |||
| t15_17= | |||
| t16_21= | |||
| t17_22= | |||
| t2_13= | |||
| t21_22= | |||
| t8_14= | |||
| t9_22= | |||
| t9_22= | |||
| tx_1= '''NOT IDENTIFIED''' | |||
| tx_17= '''PRESENT''' | |||
| tx_18= | |||
}} | }} | ||
===Diagnosis=== | ===Diagnosis=== | ||
{{hidden|Diagnosis|<center>[[ | {{hidden|Diagnosis|<center>[[Xp11 translocation renal cell carcinoma]]</center> | ||
<br> | |||
Comment:<br> | |||
These tumours are in the [[MiT family translocation renal cell carcinoma]]. They are a relatively common form of renal cell carcinoma in children; however, they are uncommon in adults. In adults they tend to have a poor prognosis.}} | |||
<br> | |||
===Other cases=== | |||
{{Cases navigation|state=collapsed}} | |||
__NOTOC__ | __NOTOC__ | ||
[[Category:Cases]] | [[Category:Cases]] | ||
[[Category:Cases in genitourinary pathology]] | |||
[[Category:Cases in molecular pathology]] | |||
[[Category:Cases difficulty 4]] | |||
[[Category:Cases in genitourinary pathology - senior]] | |||
[[Category:Cases in molecular pathology - senior]] | |||
Latest revision as of 02:21, 29 September 2015
Clinical history
45 year old woman, renal mass.
Primary image
High magnification
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Very high magnification
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Differential diagnosis
Differential diagnosis
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Additional tests
More history
More history
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Ask a friend
Ask a friend
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Stains
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IHC
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Chromosomal translocations
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Diagnosis
Diagnosis
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