Difference between revisions of "Histology artifacts"

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{{Main|Cautery artifact}}
{{Main|Cautery artifact}}


==Tissue folds==
==Tissue fold==
*Darker well demarcated line with apparent disruption of the architecture.
*Darker well demarcated line with apparent disruption of the architecture.
===Images===
<gallery>
<gallery>
Image:Basal cell hyperplasia of the prostate -- high mag.jpg | Tissue fold (center of image) in [[basal cell hyperplasia of the prostate]].  
Image:Basal cell hyperplasia of the prostate -- high mag.jpg | Tissue fold (center of image) in [[basal cell hyperplasia of the prostate]].  
Image: Sessile serrated adenoma -- low mag.jpg | Extensive tissue folding in a [[SSA]].
</gallery>
</gallery>
==Chatter artifact==
*Fine parallel lines.
===Images===
<gallery>
Image:Tubular_adenoma_2_high_mag.jpg | Chatter artifact in [[traditional adenoma|tubular adenoma]].
Image:Complex_endometrial_hyperplasia_--_high_mag.jpg | Chatter artifact in [[complex endometrial hyperplasia]].
Image:Tumour_infiltrating_lymphocytes_in_colorectal_carcinoma_-_high_mag.jpg | Chatter artifact in [[TILs]].
</gallery>
==Tissue tearing==
*Usually due to something intrinsic to the tissue that is hard, e.g. calcium.
===Image===
<gallery>
Image:Tooth_in_teratoma_-_very_low_mag.jpg | Tearing due to a calcification.
</gallery>
==Sponge artifact==
*Angulated pieces of tissue with punched-out missing fragments.<ref name=pmid2252429>{{cite journal |author=Landas SK, Bromley CM |title=Sponge artifact in biopsy specimens |journal=Arch. Pathol. Lab. Med. |volume=114 |issue=12 |pages=1285–7 |year=1990 |month=December |pmid=2252429 |doi= |url=}}</ref>
*May result in little squares of tissue arranged in a regular pattern.
===Images===
<gallery>
Image: Endometrium with sponge artifact -- very low mag.jpg | Sponge artifact - very low mag.
Image: Endometrium with sponge artifact -- low mag.jpg | Sponge artifact - low mag.
Image: Endometrium with sponge artifact -- intermed mag.jpg | Sponge artifact - intermed. mag.
</gallery>
==Bubble artifact==
===Large===
*Large bubbles of air under the cover slip.
====Images====
<gallery>
Image: Coverslip artifact -- intermed mag.jpg | CA - intermed. mag. (WC)
Image: Coverslip artifact -- high mag.jpg | CA - high mag. (WC)
Image: Coverslip artifact - alt -- high mag.jpg | CA - high mag. (WC)
</gallery>
==Coverslip artifact==
Features:
*Black-grey lines - takes on the outline of the tissue beneath it.
*Above the plane-of-focus of the tissue - '''key feature'''.
===Images===
====Case 1====
<gallery>
Image: Epididymis with coverslip artifact -- low mag.jpg | CSA - low mag. (WC)
Image: Epididymis with coverslip artifact -- intermed mag.jpg | CSA - intermed mag. (WC)
Image: Epididymis with coverslip artifact -- high mag.jpg | CSA - high mag. (WC)
Image: Epididymis with coverslip artifact - wc -- high mag.jpg | CSA - high mag. (WC)
Image: Epididymis with coverslip artifact - wc -- very high mag.jpg | CSA - very high mag. (WC)
</gallery>
==See also==
*[[Tissue loss]].
*[[Tissue floater]].
*[[Quality]].
*[[Foreign material]].
==References==
{{Reflist|1}}


==External links==
==External links==

Latest revision as of 16:21, 3 January 2020

Histology artifacts are common.

Cautery artifact

Main article: Cautery artifact

Tissue fold

  • Darker well demarcated line with apparent disruption of the architecture.

Images

Chatter artifact

  • Fine parallel lines.

Images

Tissue tearing

  • Usually due to something intrinsic to the tissue that is hard, e.g. calcium.

Image

  • Tearing due to a calcification.

Sponge artifact

  • Angulated pieces of tissue with punched-out missing fragments.[1]
  • May result in little squares of tissue arranged in a regular pattern.

Images

  • Sponge artifact - very low mag.

  • Sponge artifact - low mag.

  • Sponge artifact - intermed. mag.

Bubble artifact

Large

  • Large bubbles of air under the cover slip.

Images

  • CA - intermed. mag. (WC)

  • CA - high mag. (WC)

  • CA - high mag. (WC)

Coverslip artifact

Features:

  • Black-grey lines - takes on the outline of the tissue beneath it.
  • Above the plane-of-focus of the tissue - key feature.

Images

Case 1

  • CSA - low mag. (WC)

  • CSA - intermed mag. (WC)

  • CSA - high mag. (WC)

  • CSA - high mag. (WC)

  • CSA - very high mag. (WC)

See also

References

  1. ↑ Landas SK, Bromley CM (December 1990). "Sponge artifact in biopsy specimens". Arch. Pathol. Lab. Med. 114 (12): 1285–7. PMID 2252429.

External links

Retrieved from "https://librepathology.org/w/index.php?title=Histology_artifacts&oldid=50644"