Difference between revisions of "Gross cystic disease fluid protein-15"
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'''Gross cystic disease fluid protein-15''', usually abbreviated '''GCDFP-15''' and sometimes '''GCDFP''', is an [[immunostain]] help used to identify [[breast carcinoma]]. | '''Gross cystic disease fluid protein-15''', usually abbreviated '''GCDFP-15''' and sometimes '''GCDFP''', is an [[immunostain]] help used to identify [[breast carcinoma]]. | ||
It is much less sensitive than | It is also known as '''BRST-2'''.<ref name=pmid8693878>{{Cite journal | last1 = Fiel | first1 = MI. | last2 = Cernaianu | first2 = G. | last3 = Burstein | first3 = DE. | last4 = Batheja | first4 = N. | title = Value of GCDFP-15 (BRST-2) as a specific immunocytochemical marker for breast carcinoma in cytologic specimens. | journal = Acta Cytol | volume = 40 | issue = 4 | pages = 637-41 | month = | year = | doi = | PMID = 8693878 }}</ref> | ||
It is much less sensitive than mammaglobin.<ref>{{Cite journal | last1 = Bhargava | first1 = R. | last2 = Beriwal | first2 = S. | last3 = Dabbs | first3 = DJ. | title = Mammaglobin vs GCDFP-15: an immunohistologic validation survey for sensitivity and specificity. | journal = Am J Clin Pathol | volume = 127 | issue = 1 | pages = 103-13 | month = Jan | year = 2007 | doi = 10.1309/TDP92PQLDE2HLEET | PMID = 17145637 }}</ref> | |||
==Microscopic== | ==Microscopic== | ||
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===Images=== | ===Images=== | ||
www: | www: | ||
*[http://www.ptglab.com/Products/Pictures/PIP,GCDFP-15-Antibody-16068-1-AP-IHC18483.jpg GCDFP-15 (ptglab.com)]. | *[http://www.ptglab.com/Products/Pictures/PIP,GCDFP-15-Antibody-16068-1-AP-IHC18483.jpg GCDFP-15 (ptglab.com)]. | ||
==See also== | ==See also== | ||
Latest revision as of 15:42, 28 September 2018
Gross cystic disease fluid protein-15, usually abbreviated GCDFP-15 and sometimes GCDFP, is an immunostain help used to identify breast carcinoma.
It is also known as BRST-2.[1]
It is much less sensitive than mammaglobin.[2]
Microscopic
Features:
- Cytoplasmic staining.
Images
www:
See also
References
- ↑ Fiel, MI.; Cernaianu, G.; Burstein, DE.; Batheja, N.. "Value of GCDFP-15 (BRST-2) as a specific immunocytochemical marker for breast carcinoma in cytologic specimens.". Acta Cytol 40 (4): 637-41. PMID 8693878.
- ↑ Bhargava, R.; Beriwal, S.; Dabbs, DJ. (Jan 2007). "Mammaglobin vs GCDFP-15: an immunohistologic validation survey for sensitivity and specificity.". Am J Clin Pathol 127 (1): 103-13. doi:10.1309/TDP92PQLDE2HLEET. PMID 17145637.