Difference between revisions of "Fibroepithelial polyp"

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'''Fibroepithelial polyp''', also known as '''acrochordon''' and '''skin tag''', is a very common benign skin lesion.
'''Fibroepithelial polyp''', also known as '''acrochordon''' and '''skin tag''', is a very common benign skin lesion.


The lesion in the mouth is dealt with in the article ''[[oral fibroma]]''.
==General==
==General==
*Benign.
*Benign.
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*May be associated with pregnancy, [[diabetes]], [[intestinal polyposis]].<ref name=Ref_PCPBoD8|596>{{Ref PCPBoD8|596}}</ref>
*May be associated with pregnancy, [[diabetes]], [[intestinal polyposis]].<ref name=Ref_PCPBoD8|596>{{Ref PCPBoD8|596}}</ref>
*Can be a component of ''[[Birt–Hogg–Dubé syndrome]]''.
*Can be a component of ''[[Birt–Hogg–Dubé syndrome]]''.
May be divided into:
*Epithelial type - abundant epithelium.
*Stromal type - abundant fibrous stroma.


==Gross==
==Gross==
*Raised skin-coloured lesion.
*Raised skin-coloured lesion.


Image:
DDx - clinical:
*[http://commons.wikimedia.org/wiki/File:Skintagblemish.jpg Skin tag (WC)].
*Skin tag-like nevus.
 
===Image===
<gallery>
Image:Skintagblemish.jpg | Skin tag. (WC)
</gallery>


==Microscopic==
==Microscopic==
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*[[Nevus lipomatosus superficialis]] - abundant adipocytes in the superficial dermis.
*[[Nevus lipomatosus superficialis]] - abundant adipocytes in the superficial dermis.
*[[Neurofibroma]].
*[[Neurofibroma]].
*[[Seborrheic keratosis]] - usu. horn cysts.


===Images===
===Images===
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*[http://www.surgicalpathologyatlas.com/glfusion/mediagallery/media.php?f=0&sort=0&s=20080802171929218 Fibroepithelial polyp (surgicalpathologyatlas.com)].
*[http://www.surgicalpathologyatlas.com/glfusion/mediagallery/media.php?f=0&sort=0&s=20080802171929218 Fibroepithelial polyp (surgicalpathologyatlas.com)].
*[http://dermatology-s10.cdlib.org/143/case_presentations/skintags/3.jpg Inflamed fibroepithelial polyp (cdlib.org)].<ref>URL: [http://dermatology-s10.cdlib.org/143/case_presentations/skintags/allegue.html http://dermatology-s10.cdlib.org/143/case_presentations/skintags/allegue.html]. Accessed on: 9 January 2013.</ref>
*[http://dermatology-s10.cdlib.org/143/case_presentations/skintags/3.jpg Inflamed fibroepithelial polyp (cdlib.org)].<ref>URL: [http://dermatology-s10.cdlib.org/143/case_presentations/skintags/allegue.html http://dermatology-s10.cdlib.org/143/case_presentations/skintags/allegue.html]. Accessed on: 9 January 2013.</ref>
==Sign out==
==Sign out==
<pre>
<pre>
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===Micro===
===Micro===
The sections show a fragment of skin with epithelium on three sides.  The epithelium matures normally and is not hypertrophic.  Orthokeratosis is present. The core of the lesion has fibrous tissue.  There is no significant inflammation. No melanocytic nests are identified.
The sections show a fragment of skin with epithelium on three sides.  The epithelium matures normally and is not hypertrophic.  Orthokeratosis is present. The core of the lesion has fibrous tissue.  There is no significant inflammation. No melanocytic nests are identified.
====Hyperkeratosis====
The sections show a fragment of skin with epithelium on three sides. The epidermis matures
toward the surface and no significant basilar atypia is identified. A prominent granular layer is present. Mild hyperkeratosis is present. The core of the lesion consists of fibrous tissue. There is no significant inflammation. No
melanocytic nests are identified.


====Inflamed====  
====Inflamed====  
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There is mild basal nuclear enlargement.  No significant nuclear atypia is apparent. The
There is mild basal nuclear enlargement.  No significant nuclear atypia is apparent. The
dermal-epidermal interface is well-demarcated. Rare basal mitotic activity is identified.
dermal-epidermal interface is well-demarcated. Rare basal mitotic activity is identified.
====Epithelial-type====
The sections show skin with epithelium on three sides, acanthosis and hyperkeratosis. No pseudohorn cysts are identified. A granular layer is present. Mild basal
nuclear atypia is present. Mitotic activity is present but basal. Minimal parakeratosis is
present. No melanocytic nests are identified. No solar elastosis is apparent in the limited
dermis. No koilocytes are apparent.


==See also==
==See also==
*[[Non-malignant skin disease]].
*[[Non-malignant skin disease]].
*[[Eyelid]].


==References==
==References==

Latest revision as of 13:51, 25 November 2015

Fibroepithelial polyp
Diagnosis in short

Fibroepithelial polyp. H&E stain.
LM On a stalk / epithelium on three sides, benign epidermis, fibrous core, +/-inflammation
LM DDx Regressing melanocytic lesions (esp. intradermal melanocytic nevus), pedunculated seborrheic keratosis, nevus lipomatosus superficialis, neurofibroma
Gross raised skin-coloured lesion
Site skin
Syndromes Birt–Hogg–Dubé syndrome
Prevalence very common
Prognosis benign

Fibroepithelial polyp, also known as acrochordon and skin tag, is a very common benign skin lesion.

The lesion in the mouth is dealt with in the article oral fibroma.

General

May be divided into:

  • Epithelial type - abundant epithelium.
  • Stromal type - abundant fibrous stroma.

Gross

  • Raised skin-coloured lesion.

DDx - clinical:

  • Skin tag-like nevus.

Image

  • Skin tag. (WC)

Microscopic

Features:

  • On a stalk / epithelium on three sides.
  • Benign epidermis.
  • Fibrous core.
  • +/-Inflammation.

DDx:

Images

  • Skin tag. (WC)

www:

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EYELID ("TAG"), RIGHT, REMOVAL:
- BENIGN FIBROEPITHELIAL POLYP.

SKIN ("SKIN TAG"), THIGH, REMOVAL:
- FIBROEPITHELIAL POLYP.

Micro

The sections show a fragment of skin with epithelium on three sides. The epithelium matures normally and is not hypertrophic. Orthokeratosis is present. The core of the lesion has fibrous tissue. There is no significant inflammation. No melanocytic nests are identified.

Hyperkeratosis

The sections show a fragment of skin with epithelium on three sides. The epidermis matures toward the surface and no significant basilar atypia is identified. A prominent granular layer is present. Mild hyperkeratosis is present. The core of the lesion consists of fibrous tissue. There is no significant inflammation. No melanocytic nests are identified.

Inflamed

The sections show a fragment of skin with epithelium on three sides. The epithelium matures and is acanthotic. Minimal parakeratosis is present. The core of the lesion consists of fibrous tissue with a mild lymphocyte-predominant dermal infiltrate. Rare siderophages are present.

There is mild basal nuclear enlargement. No significant nuclear atypia is apparent. The dermal-epidermal interface is well-demarcated. Rare basal mitotic activity is identified.

Epithelial-type

The sections show skin with epithelium on three sides, acanthosis and hyperkeratosis. No pseudohorn cysts are identified. A granular layer is present. Mild basal nuclear atypia is present. Mitotic activity is present but basal. Minimal parakeratosis is present. No melanocytic nests are identified. No solar elastosis is apparent in the limited dermis. No koilocytes are apparent.

See also

References

  1. ↑ Mitchell, Richard; Kumar, Vinay; Fausto, Nelson; Abbas, Abul K.; Aster, Jon (2011). Pocket Companion to Robbins & Cotran Pathologic Basis of Disease (8th ed.). Elsevier Saunders. pp. 596. ISBN 978-1416054542.
  2. ↑ Busam, Klaus J. (2009). Dermatopathology: A Volume in the Foundations in Diagnostic Pathology Series (1st ed.). Saunders. pp. 342. ISBN 978-0443066542.
  3. ↑ URL: http://dermatlas.med.jhmi.edu/derm/result.cfm?Diagnosis=1196583692. Accessed on: 1 September 2011.
  4. ↑ URL: http://dermatology-s10.cdlib.org/143/case_presentations/skintags/allegue.html. Accessed on: 9 January 2013.
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