Difference between revisions of "Intramuscular myxoma"
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| Width = | | Width = | ||
| Caption = Intramuscular myxoma. | | Caption = Intramuscular myxoma. | ||
| Micro = | | Micro = myxoid stroma with bland stellate cells and/or bland spindle cells, intramuscular, usu. hypervascular and hypercellular | ||
| Subtypes = | | Subtypes = hypercellular, hypervascular | ||
| LMDDx = [[myxoid lesions]] | | LMDDx = [[myxoid lesions]] | ||
| Stains = | | Stains = | ||
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| Gross = | | Gross = | ||
| Grossing = | | Grossing = | ||
| Site = [[ | | Site = [[soft tissue]] | ||
| Assdx = | | Assdx = | ||
| Syndromes = | | Syndromes = | ||
| Clinicalhx = | |||
| Signs = | | Signs = | ||
| Symptoms = | | Symptoms = | ||
| Prevalence = | | Prevalence = rare | ||
| Bloodwork = | | Bloodwork = | ||
| Rads = | | Rads = | ||
| Endoscopy = | | Endoscopy = | ||
| Prognosis = | | Prognosis = benign, rarely recur | ||
| Other = | | Other = | ||
| ClinDDx = | | ClinDDx = | ||
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==Microscopic== | ==Microscopic== | ||
Features:<ref name=pmid15663047/> | Features:<ref name=pmid15663047/><ref name=pmid9777984/> | ||
*Myxoid stroma. | *Myxoid stroma - '''key feature''' | ||
** | *Bland stellate or spindle cells. | ||
** | **Typically paucicellular. † | ||
*Contained within skeletal muscle. | **Usually with scant vascularity. ‡ | ||
*Contained within skeletal muscle - '''essential'''. | |||
DDx: | Note: | ||
*† A hypercellular variant exists. | |||
*‡ A hypervascular variant exists. | |||
DDx:<ref name=pmid9777984>{{Cite journal | last1 = Nielsen | first1 = GP. | last2 = O'Connell | first2 = JX. | last3 = Rosenberg | first3 = AE. | title = Intramuscular myxoma: a clinicopathologic study of 51 cases with emphasis on hypercellular and hypervascular variants. | journal = Am J Surg Pathol | volume = 22 | issue = 10 | pages = 1222-7 | month = Oct | year = 1998 | doi = | PMID = 9777984 }}</ref> | |||
*[[Low-grade fibromyxoid sarcoma]].<ref name=pmid23685711>{{Cite journal | last1 = Yamashita | first1 = H. | last2 = Endo | first2 = K. | last3 = Takeda | first3 = C. | last4 = Teshima | first4 = R. | last5 = Osaki | first5 = M. | last6 = Yoshida | first6 = H. | title = Intramuscular myxoma of the buttock mimicking low-grade fibromyxoid sarcoma: diagnostic usefulness of MUC4 expression. | journal = Skeletal Radiol | volume = | issue = | pages = | month = May | year = 2013 | doi = 10.1007/s00256-013-1641-4 | PMID = 23685711 }}</ref> | *[[Low-grade fibromyxoid sarcoma]].<ref name=pmid23685711>{{Cite journal | last1 = Yamashita | first1 = H. | last2 = Endo | first2 = K. | last3 = Takeda | first3 = C. | last4 = Teshima | first4 = R. | last5 = Osaki | first5 = M. | last6 = Yoshida | first6 = H. | title = Intramuscular myxoma of the buttock mimicking low-grade fibromyxoid sarcoma: diagnostic usefulness of MUC4 expression. | journal = Skeletal Radiol | volume = | issue = | pages = | month = May | year = 2013 | doi = 10.1007/s00256-013-1641-4 | PMID = 23685711 }}</ref> | ||
*[[Myxoid liposarcoma]]. | |||
*[[Myxofibrosarcoma]] | |||
*[[Juxta-articular myxoma]]. | |||
===Images=== | ===Images=== | ||
<gallery> | <gallery> | ||
Image: Intramuscular myxoma - low mag.jpg | Low mag. (WC/Nephron) | Image: Intramuscular myxoma - low mag.jpg | Low mag. (WC/Nephron) | ||
Image: Intramuscular myxoma - intermed mag.jpg | Intermed. mag. (WC/Nephron) | Image: Intramuscular myxoma - intermed mag.jpg | Intermed. mag. (WC/Nephron) | ||
| Line 62: | Line 70: | ||
==References== | ==References== | ||
{{Reflist| | {{Reflist|2}} | ||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Soft tissue lesions]] | [[Category:Soft tissue lesions]] | ||
Latest revision as of 20:54, 5 July 2013
| Intramuscular myxoma | |
|---|---|
| Diagnosis in short | |
 Intramuscular myxoma. | |
|
| |
| LM | myxoid stroma with bland stellate cells and/or bland spindle cells, intramuscular, usu. hypervascular and hypercellular |
| Subtypes | hypercellular, hypervascular |
| LM DDx | myxoid lesions |
| Site | soft tissue |
|
| |
| Prevalence | rare |
| Prognosis | benign, rarely recur |
Intramuscular myxoma is an uncommon benign intramuscular myxoid lesion.
General
Gross
- Usually thigh muscles.[2]
Microscopic
- Myxoid stroma - key feature
- Bland stellate or spindle cells.
- Typically paucicellular. †
- Usually with scant vascularity. ‡
- Contained within skeletal muscle - essential.
Note:
- † A hypercellular variant exists.
- ‡ A hypervascular variant exists.
DDx:[3]
Images
Low mag. (WC/Nephron)
Intermed. mag. (WC/Nephron)
Intermed. mag. (WC/Nephron)
Intermed. mag. (WC/Nephron)
High mag. (WC/Nephron)
Very high mag. (WC/Nephron)
See also
References
- ↑ 1.0 1.1 Charron, P.; Smith, J. (Dec 2004). "Intramuscular myxomas: a clinicopathologic study with emphasis on surgical management.". Am Surg 70 (12): 1073-7. PMID 15663047.
- ↑ 2.0 2.1 2.2 Silver, WP.; Harrelson, JM.; Scully, SP. (Oct 2002). "Intramuscular myxoma: a clinicopathologic study of 17 patients.". Clin Orthop Relat Res (403): 191-7. PMID 12360026.
- ↑ 3.0 3.1 Nielsen, GP.; O'Connell, JX.; Rosenberg, AE. (Oct 1998). "Intramuscular myxoma: a clinicopathologic study of 51 cases with emphasis on hypercellular and hypervascular variants.". Am J Surg Pathol 22 (10): 1222-7. PMID 9777984.
- ↑ Yamashita, H.; Endo, K.; Takeda, C.; Teshima, R.; Osaki, M.; Yoshida, H. (May 2013). "Intramuscular myxoma of the buttock mimicking low-grade fibromyxoid sarcoma: diagnostic usefulness of MUC4 expression.". Skeletal Radiol. doi:10.1007/s00256-013-1641-4. PMID 23685711.