Difference between revisions of "Ferruginous body"
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[[Image:Ferruginous bodies - BAL - r3 -- very high mag.jpg|right|thumb|300px|Ferruginous body in a BAL. (WC)]] | |||
'''Ferruginous body''' is a histopathologic finding in [[lung pathology]] that strongly suggests exposure to asbestos. | |||
==General== | |||
*Uncommon finding. | |||
*Strongly suggestive of asbestos exposure. | |||
Conditions associated with asbestos exposure (mnemonic ''PALM''):<ref name=Ref_PCPBoD8_375>{{Ref PCPBoD8|375}}</ref> | |||
*[[Pleural plaques]]. | |||
*[[Asbestosis]]. | |||
*[[Lung carcinoma]]. | |||
*[[Malignant mesothelioma]]. | |||
==Microscopic== | |||
Features: | |||
*Segmented twirling baton-like structure (approximately 3-5 micrometres x 20-80 micrometres) with long slender fibre within. | |||
*Black/brown crystal-like appearance. | |||
DDx: | |||
*Dirt - especially on H&E. | |||
===Images=== | |||
<gallery> | |||
Image:Ferruginous_body.jpg | Ferruginous bodies. (WC) | |||
</gallery> | |||
====Cytology==== | |||
<gallery> | |||
Image: Ferruginous bodies - BAL - r1 -- high mag.jpg | FB - high mag. (WC) | |||
Image: Ferruginous bodies - BAL - r1 -- very high mag.jpg | FB - very high mag. (WC) | |||
Image: Ferruginous bodies - BAL - r2 -- very high mag.jpg | FB - very high mag. (WC) | |||
Image: Ferruginous bodies - BAL - r3 -- high mag.jpg | FB - high mag. (WC) | |||
Image: Ferruginous bodies - BAL - r3 -- very high mag.jpg | FB - very high mag. (WC) | |||
Image:Carcinoma asbestos body lung.jpg | Ferruginous body in carcinoma - cytology. (WC/Alex Brollo) | |||
</gallery> | |||
==Stains== | |||
*[[Prussian blue stain]] +ve. | |||
==Sign out== | |||
<pre> | |||
Comment: | |||
No cell block is available for further work-up, e.g. iron staining. | |||
The findings herein should be correlated with imaging and the clinical history. | |||
Ferruginous bodies are associated asbestos exposure. | |||
</pre> | |||
==See also== | |||
*[[Malignant mesothelioma]]. | |||
==References== | |||
{{Reflist|1}} | |||
[[Category:Pulmonary pathology]] | |||
Latest revision as of 17:46, 20 May 2018
Ferruginous body is a histopathologic finding in lung pathology that strongly suggests exposure to asbestos.
General
- Uncommon finding.
- Strongly suggestive of asbestos exposure.
Conditions associated with asbestos exposure (mnemonic PALM):[1]
Microscopic
Features:
- Segmented twirling baton-like structure (approximately 3-5 micrometres x 20-80 micrometres) with long slender fibre within.
- Black/brown crystal-like appearance.
DDx:
- Dirt - especially on H&E.
Images
Ferruginous bodies. (WC)
Cytology
FB - high mag. (WC)
FB - very high mag. (WC)
FB - very high mag. (WC)
FB - high mag. (WC)
FB - very high mag. (WC)
Ferruginous body in carcinoma - cytology. (WC/Alex Brollo)
Stains
- Prussian blue stain +ve.
Sign out
Comment: No cell block is available for further work-up, e.g. iron staining. The findings herein should be correlated with imaging and the clinical history. Ferruginous bodies are associated asbestos exposure.
See also
References
- ↑ Mitchell, Richard; Kumar, Vinay; Fausto, Nelson; Abbas, Abul K.; Aster, Jon (2011). Pocket Companion to Robbins & Cotran Pathologic Basis of Disease (8th ed.). Elsevier Saunders. pp. 375. ISBN 978-1416054542.