Difference between revisions of "Autopsy"
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===Nephrosclerosis=== | ===Nephrosclerosis=== | ||
*''Flea-bitten appearance'' - seen in hypertension.<ref name=pmid9356598>PMID 9356598 | *''Flea-bitten appearance'' - seen in hypertension.<ref name=pmid9356598>{{Cite journal | last1 = Ono | first1 = H. | last2 = Ono | first2 = Y. | title = Nephrosclerosis and hypertension. | journal = Med Clin North Am | volume = 81 | issue = 6 | pages = 1273-88 | month = Nov | year = 1997 | doi = | PMID = 9356598 }} | ||
</ref> | |||
===ATN=== | ===ATN=== | ||
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==Weird stuff== | ==Weird stuff== | ||
*''Methylene blue'', used for refractory shock,<ref name=pmid17926021>PMID 17926021</ref> turns organs green.<ref>PMID 18703358</ref> | *''Methylene blue'', used for refractory shock,<ref name=pmid17926021>{{Cite journal | last1 = Heemskerk | first1 = S. | last2 = van Haren | first2 = FM. | last3 = Foudraine | first3 = NA. | last4 = Peters | first4 = WH. | last5 = van der Hoeven | first5 = JG. | last6 = Russel | first6 = FG. | last7 = Masereeuw | first7 = R. | last8 = Pickkers | first8 = P. | title = Short-term beneficial effects of methylene blue on kidney damage in septic shock patients. | journal = Intensive Care Med | volume = 34 | issue = 2 | pages = 350-4 | month = Feb | year = 2008 | doi = 10.1007/s00134-007-0867-9 | PMID = 17926021 }} | ||
</ref> turns organs green.<ref name=pmid18703358>{{Cite journal | last1 = Tan | first1 = CD. | last2 = Rodriguez | first2 = ER. | title = Blue dye, green heart. | journal = Cardiovasc Pathol | volume = 19 | issue = 2 | pages = 125-6 | month = | year = | doi = 10.1016/j.carpath.2008.06.012 | PMID = 18703358 }}</ref> | |||
*''Leukostasis'' in [[acute myelogenous leukemia]] can lead to congestion of organs and fatal haemorrhages. | *''Leukostasis'' in [[acute myelogenous leukemia]] can lead to congestion of organs and fatal haemorrhages. | ||
Revision as of 02:39, 29 June 2010
Autopsy is a part of pathology.
External exam
Is very important in the forensic context.
Internal exam
Is usually where the money is in non-forensic autopsies, i.e. hospital autopsies.
Spleen
Sugar-coated spleen
- Properly referred to as hyaloserositis of the spleen.
- Capsule of the spleen is white - resembles sugar-coating.
- Importance: none - benign.
Liver
- Portal vein patency.
Kidney
Size of the kidney - small kidneys are seen in chronic renal failure.
Nephrosclerosis
- Flea-bitten appearance - seen in hypertension.[1]
ATN
- ATN is difficult to prove on autopsy material.
- Look for:
- Heme-granular casts in the lumen.
- Regenerative activity (mitoses).
Weird stuff
- Leukostasis in acute myelogenous leukemia can lead to congestion of organs and fatal haemorrhages.
- Hyperviscosity syndrome - in leukemia.[4]
Todo
- Normal organ mass.
See also
References
- ↑ Ono, H.; Ono, Y. (Nov 1997). "Nephrosclerosis and hypertension.". Med Clin North Am 81 (6): 1273-88. PMID 9356598.
- ↑ Heemskerk, S.; van Haren, FM.; Foudraine, NA.; Peters, WH.; van der Hoeven, JG.; Russel, FG.; Masereeuw, R.; Pickkers, P. (Feb 2008). "Short-term beneficial effects of methylene blue on kidney damage in septic shock patients.". Intensive Care Med 34 (2): 350-4. doi:10.1007/s00134-007-0867-9. PMID 17926021.
- ↑ Tan, CD.; Rodriguez, ER.. "Blue dye, green heart.". Cardiovasc Pathol 19 (2): 125-6. doi:10.1016/j.carpath.2008.06.012. PMID 18703358.
- ↑ http://cat.inist.fr/?aModele=afficheN&cpsidt=18942659