Difference between revisions of "Intranodal palisaded myofibroblastoma"
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Features: | Features: | ||
#Rim of peripheral lymphoid tissue. | #Rim of peripheral lymphoid tissue. | ||
# | #Spindle cells with nuclear palisading - '''key feature'''. | ||
#RBC extravasation/hemorrhage. | #RBC extravasation/hemorrhage. | ||
#Amianthoid fibers - blood vessel surrounded by collagen with peripheral spokes.<ref name=pmid1918406>{{Cite journal | last1 = Bigotti | first1 = G. | last2 = Coli | first2 = A. | last3 = Mottolese | first3 = M. | last4 = Di Filippo | first4 = F. | title = Selective location of palisaded myofibroblastoma with amianthoid fibres. | journal = J Clin Pathol | volume = 44 | issue = 9 | pages = 761-4 | month = Sep | year = 1991 | doi = | PMID = 1918406 }}</ref> | #Amianthoid fibers - blood vessel surrounded by collagen with peripheral spokes.<ref name=pmid1918406>{{Cite journal | last1 = Bigotti | first1 = G. | last2 = Coli | first2 = A. | last3 = Mottolese | first3 = M. | last4 = Di Filippo | first4 = F. | title = Selective location of palisaded myofibroblastoma with amianthoid fibres. | journal = J Clin Pathol | volume = 44 | issue = 9 | pages = 761-4 | month = Sep | year = 1991 | doi = | PMID = 1918406 }}</ref> | ||
# | #Intracellular and extracellular fuchsinophilic bodies. | ||
#*Smooth muscle actin. | |||
DDx: | DDx: | ||
Revision as of 03:34, 4 October 2011
Intranodal palisaded myofibroblastoma, abbreviated IPM, is a rare tumour that classically presents as an inguinal mass.[1]
General
- Rare.
- Male:female = 2:1.
- Adults - middle age.
Microscopic
Features:
- Rim of peripheral lymphoid tissue.
- Spindle cells with nuclear palisading - key feature.
- RBC extravasation/hemorrhage.
- Amianthoid fibers - blood vessel surrounded by collagen with peripheral spokes.[2]
- Intracellular and extracellular fuchsinophilic bodies.
- Smooth muscle actin.
DDx:
Images:
IHC
- SMA +ve.
- Cyclin D1 +ve.
Other:
- S100 -ve
- Excludes schwannoma.
- GFAP -ve.
- CD34 -ve.
- Desmin -ve
- Ki-67 - low.
See also
References
- ↑ Nguyen, T.; Eltorky, MA. (Feb 2007). "Intranodal palisaded myofibroblastoma.". Arch Pathol Lab Med 131 (2): 306-10. doi:10.1043/1543-2165(2007)131[306:IPM]2.0.CO;2. PMID 17284119.
- ↑ 2.0 2.1 Bigotti, G.; Coli, A.; Mottolese, M.; Di Filippo, F. (Sep 1991). "Selective location of palisaded myofibroblastoma with amianthoid fibres.". J Clin Pathol 44 (9): 761-4. PMID 1918406.