Difference between revisions of "Morphologic patterns"
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The article deals with '''morphologic patterns''' in pathology. It is focused on light microscopy. | The article deals with '''morphologic patterns''' in [[pathology]]. It is focused on light microscopy. | ||
''Histomorphology'' redirects here. | |||
==The big table of morphology== | ==The big table of morphology== | ||
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! Image | ! Image | ||
|- | |- | ||
| Hobnail | | [[Glandular]] | ||
| excretory structure, invagination when seen in 3 dimensions, may be round structures in cross-section or have an irregular shape | |||
| [[adenocarcinoma]] | |||
| [[Image:Colorectal adenocarcinoma -- low mag.jpg |thumb|center|150px| [[Colorectal adenocarcinoma]] - low mag. (WC/Nephron)]] | |||
|- | |||
| [[Hobnail]] | |||
| basement membrane area < area exposed to luminal surface | | basement membrane area < area exposed to luminal surface | ||
| [[angiosarcoma]], clear cell carcinoma | | [[angiosarcoma]], clear cell carcinoma | ||
| Line 43: | Line 50: | ||
| [[File:Invasive_micropapillary_carcinoma_of_the_breast.jpg|thumb|center|150px|Micropapillary carcinoma. (WC)]] | | [[File:Invasive_micropapillary_carcinoma_of_the_breast.jpg|thumb|center|150px|Micropapillary carcinoma. (WC)]] | ||
|- | |- | ||
| Papillary | | [[Papillary]] | ||
| nipple-like projection with a fibrovascular core | | nipple-like projection with a fibrovascular core | ||
| [[papillary thyroid carcinoma]] | | [[papillary thyroid carcinoma]] | ||
| Line 50: | Line 57: | ||
| Flat | | Flat | ||
| board-like, does not have a projection above the surface | | board-like, does not have a projection above the surface | ||
| flat DCIS | | flat [[DCIS]], [[urothelial carcinoma in situ]] | ||
| [ | | [[Image:Urothelial_carcinoma_in_situ_--_high_mag.jpg| thumb|center|150px|[[Urothelial carcinoma in situ]] - high mag. (WC/Nephron)]] | ||
|- | |- | ||
| Herring bone | | [[Herring bone]] | ||
| like herring bone (technique) for climbing a hill in cross country skiing; books on a shelf, where they have partially fallen over -- on the one shelf to the left and the one below to the right | | like herring bone (technique) for climbing a hill in cross country skiing; books on a shelf, where they have partially fallen over -- on the one shelf to the left and the one below to the right | ||
| [[fibrosarcoma]], [[synovial sarcoma]], [[MPNST]] | | [[fibrosarcoma]], [[synovial sarcoma]], [[MPNST]] | ||
| Line 73: | Line 80: | ||
| [[Image:Desmoplastic_small_round_cell_tumour_-_high_mag.jpg |thumb|center|150px| [[DSRCT]] - high mag. (WC/Nephron)]] | | [[Image:Desmoplastic_small_round_cell_tumour_-_high_mag.jpg |thumb|center|150px| [[DSRCT]] - high mag. (WC/Nephron)]] | ||
|} | |} | ||
==Patterns== | |||
===Hobnail pattern=== | |||
{{Main|Hobnail pattern}} | |||
==See also== | ==See also== | ||
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[[Category:Basics]] | [[Category:Basics]] | ||
[[Category:Morphologic patterns]] | |||
Latest revision as of 14:01, 26 February 2025
The article deals with morphologic patterns in pathology. It is focused on light microscopy.
Histomorphology redirects here.
The big table of morphology
| Name of pattern | Meaning | DDx (incomplete/abbrev. list) | Image |
|---|---|---|---|
| Glandular | excretory structure, invagination when seen in 3 dimensions, may be round structures in cross-section or have an irregular shape | adenocarcinoma | File:Colorectal adenocarcinoma -- low mag.jpg Colorectal adenocarcinoma - low mag. (WC/Nephron) |
| Hobnail | basement membrane area < area exposed to luminal surface | angiosarcoma, clear cell carcinoma | File:Epithelioid angiosarcoma - very high mag.jpg Angiosarcoma - very high mag. (WC/Nephron) |
| Storiform | spiral appearance or cartwhell pattern[1] | solitary fibrous tumour, DFSP, dermatofibroma, UPS | File:Storiform pattern - very high mag.jpg DFSP - very high mag. (WC/Nephron) |
| Fascicular | the long axis of the (spindle) cells are perpendicular to one another in adjacent bundles of cells | leiomyoma, leiomyosarcoma | File:Cutaneous leiomyosarcoma - very high mag.jpg Leiomyosarcoma - very high mag. (WC/Nephron) |
| Plexiform | web-like formation[2] | plexiform neurofibroma, MPNST, plexiform lesion of pulmonary hypertension | plexiform lesion of Pulm. HTn (flickr.com) |
| Cribriform | pierced with small holes[3] | cribriform DCIS, cribriform HGPIN, cribriforming in a tubular adenoma with high-grade dysplasia, endometrioid endometrial carcinoma |  Cribriform architecure (ADH) - very high mag. (WC/Nephron) |
| Solid or Sheeting | no architecture - back-to-back cells with no pattern apparent / no spaces between cells | solid DCIS, poorly-differentiated malignancy (carcinoma, sarcoma, lymphoma) | File:Merkel cell carcinoma - high mag.jpg Sheeting in a Merkel cell carcinoma - high mag. (WC/Nephron) |
| Micropapillary | nipple like projections without a fibrovascular core (papillary = nipple-like[4]) | micropapillary DCIS, micropapillary HGPIN | File:Invasive micropapillary carcinoma of the breast.jpg Micropapillary carcinoma. (WC) |
| Papillary | nipple-like projection with a fibrovascular core | papillary thyroid carcinoma | File:Papillary renal cell carcinoma high mag.jpg Papillary RCC - high mag. (WC/Nephron) |
| Flat | board-like, does not have a projection above the surface | flat DCIS, urothelial carcinoma in situ | File:Urothelial carcinoma in situ -- high mag.jpg Urothelial carcinoma in situ - high mag. (WC/Nephron) |
| Herring bone | like herring bone (technique) for climbing a hill in cross country skiing; books on a shelf, where they have partially fallen over -- on the one shelf to the left and the one below to the right | fibrosarcoma, synovial sarcoma, MPNST | File:Malignant peripheral nerve sheath tumour - high mag.jpg MPNST - high mag.(WC/Nephron) |
| Trabecular or cords | trabecula = little beam[5]; quasi-linear arrangement of cells | normal liver lobule, Sertoli cell tumour | File:Papillary thyroid carcinoma tall cell var high mag.jpg PTC tall cell variant - high mag. (WC/Nephron) |
| Nested (nesting) | islands of cells with a circular outline | neuroendocrine tumours | File:Small intestine neuroendocrine tumour high mag cropped.jpg Neuroendocrine tumour - low mag. (WC/Nephron) |
| Biphasic / multiple patterns | multiple patterns or cell types; e.g. spindle cells and epithelioid cells | synovial sarcoma, malignant melanoma, pleomorphic adenoma, angiomyolipoma, chondroid syringoma | File:Desmoplastic small round cell tumour - high mag.jpg DSRCT - high mag. (WC/Nephron) |
Patterns
Hobnail pattern
Main article: Hobnail pattern
See also
References
- ↑ Storiform. dictionary.com. URL: http://dictionary.reference.com/browse/storiform. Accessed on: April 24, 2009.
- ↑ URL: http://www.mondofacto.com/facts/dictionary?plexiform. Accessed on: March 9, 2010.
- ↑ URL: http://dictionary.reference.com/browse/cribriform. Accessed on: 8 August 2011.
- ↑ URL: http://dictionary.reference.com/browse/papillary. Accessed on: 8 August 2011.
- ↑ URL: http://dictionary.reference.com/browse/trabecula. Accessed on: 26 December 2010.