Difference between revisions of "Multicystic dysplastic kidney"
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*May be unilateral or involve only part of a kidney.<ref name=Ref_Klatt237>{{Ref Klatt|237}}</ref> | *May be unilateral or involve only part of a kidney.<ref name=Ref_Klatt237>{{Ref Klatt|237}}</ref> | ||
Etiology: | Etiology: | ||
*Renal collecting system forms when ''ureteric bud'' (which grows from cloaca) meets the ''renal blastema'' (kidney parenchyma precursor). | *Embryological malformation:<ref name=pmid33252759/> | ||
**Renal collecting system forms when ''ureteric bud'' (which grows from cloaca) meets the ''renal blastema'' (kidney parenchyma precursor). | |||
==Gross== | ==Gross== | ||
Revision as of 17:02, 4 February 2025
Multicystic dysplastic kidney, abbreviated MCDK, is a cystic disease of the kidney. It is also known as multicystic renal dysplasia (abbreviated as MRD).[1]
General
- Most common cause of abdominal mass in newborns.[2]
- May be unilateral or involve only part of a kidney.[3]
Etiology:
- Embryological malformation:[4]
- Renal collecting system forms when ureteric bud (which grows from cloaca) meets the renal blastema (kidney parenchyma precursor).
Gross
- Kidney has multiple large cysts or differing sizes.
DDx:
- ARPKD - has less variability of cyst size.
Images:
Microscopic
- Cystic spaces of variable size.
- Fibrous stroma.
- Islands of cartilage.
Image:
Note:
- Cysts do not communicate with one another.[4]
See also
References
- ↑ Multicystic Dysplastic Kidney. National Institutes of Health (United States). URL: https://www.niddk.nih.gov/health-information/kidney-disease/children/multicystic-dysplastic-kidney]. Accessed on: 2025-Feb-04.
- ↑ URL: http://emedicine.medscape.com/article/982560-overview. Accessed on: 4 January 2012.
- ↑ 3.0 3.1 Klatt, Edward C. (2006). Robbins and Cotran Atlas of Pathology (1st ed.). Saunders. pp. 237. ISBN 978-1416002741.
- ↑ 4.0 4.1 4.2 PubMed 33252759