Difference between revisions of "Sarcina"
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==General== | ==General== | ||
*Probably a commensal organism.<Ref name=pmid23599657/> | *Probably a commensal organism.<Ref name=pmid23599657/> | ||
*Gram positive coccus.<ref name=pmid27737866 | *Gram positive coccus.<ref name=pmid27737866/> | ||
*Uncommonly seen. | *Uncommonly seen. | ||
*Associated with gastroparesis,<ref name=pmid23599657>{{Cite journal | last1 = Ratuapli | first1 = SK. | last2 = Lam-Himlin | first2 = DM. | last3 = Heigh | first3 = RI. | title = Sarcina ventriculi of the stomach: a case report. | journal = World J Gastroenterol | volume = 19 | issue = 14 | pages = 2282-5 | month = | year = 2013 | doi = 10.3748/wjg.v19.i14.2282 | PMID = 23599657 }}</ref> as may be seen in [[diabetes mellitus]]. | *Associated with gastroparesis,<ref name=pmid23599657>{{Cite journal | last1 = Ratuapli | first1 = SK. | last2 = Lam-Himlin | first2 = DM. | last3 = Heigh | first3 = RI. | title = Sarcina ventriculi of the stomach: a case report. | journal = World J Gastroenterol | volume = 19 | issue = 14 | pages = 2282-5 | month = | year = 2013 | doi = 10.3748/wjg.v19.i14.2282 | PMID = 23599657 }}</ref> as may be seen in [[diabetes mellitus]]. | ||
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*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193598/figure/F2/ Sarcina (nih.gov)]. | *[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193598/figure/F2/ Sarcina (nih.gov)]. | ||
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627895/figure/F2/ Sarcina (nih.gov)].<ref name=pmid23599657/> | *[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627895/figure/F2/ Sarcina (nih.gov)].<ref name=pmid23599657/> | ||
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===Urine cytology=== | |||
<pre> | |||
Abundant micro-organisms compatible with Sarcina, see comment. | |||
Acute inflammation. | |||
NEGATIVE for High-Grade Urothelial Carcinoma. | |||
Comment: | |||
The micro-organisms are arranged in distinctive tetrads, as is typical for Sarcina. | |||
This is an uncommon finding.[1] Treatment should be considered within the clinical context. | |||
1. Bommannan K, Gaspar BL, Sachdeva MUS. BMJ Case Rep. 2016 Oct 13;2016:bcr2016216991. doi:10.1136/bcr-2016-216991 | |||
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073697/pdf/bcr-2016-216991.pdf | |||
</pre> | |||
==See also== | ==See also== | ||
Latest revision as of 20:21, 10 June 2022
Micrograph showing Sarcina. H&E stain. (WC/Librepath)
Sarcina organisms are occasionally seen in the gastrointestinal tract. They are reported in urine.[1]
General
- Probably a commensal organism.[2]
- Gram positive coccus.[1]
- Uncommonly seen.
- Associated with gastroparesis,[2] as may be seen in diabetes mellitus.
Described complications:[2]
- Gastric perforation.
- Emphysematous gastritis.
Notes:
- Sarcina ventriculi = Gram-positive organism.[2]
Gross
Features:
- Erythema.
- +/-Gastric ulcer.
- +/-Retained food.
Microscopic
Features:[3]
- Small essentially spherical micro-organisms.
- Each micro-organism 1.8-3 micrometres - purple on H&E stain.
- Arranged in clusters of 4, 8 or more - classically in a tetrad - key feature.
DDx:
- Micrococcus - form larger clusters.[3]
Images
Case 1
Sarcina - low mag.
Sarcina - intermed. mag.
Sarcina - intermed. mag.
Sarcina - high mag.
Sarcina - high mag.
Sarcina - very high mag.
Sarcina - very high mag.
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Urine cytology
Abundant micro-organisms compatible with Sarcina, see comment. Acute inflammation. NEGATIVE for High-Grade Urothelial Carcinoma. Comment: The micro-organisms are arranged in distinctive tetrads, as is typical for Sarcina. This is an uncommon finding.[1] Treatment should be considered within the clinical context. 1. Bommannan K, Gaspar BL, Sachdeva MUS. BMJ Case Rep. 2016 Oct 13;2016:bcr2016216991. doi:10.1136/bcr-2016-216991 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073697/pdf/bcr-2016-216991.pdf
See also
References
- ↑ 1.0 1.1 Bommannan K, Gaspar BL, Sachdeva MU (October 2016). "Pathogenic Sarcina in urine". BMJ Case Rep 2016. doi:10.1136/bcr-2016-216991. PMC 5073697. PMID 27737866. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073697/.
- ↑ 2.0 2.1 2.2 2.3 2.4 Ratuapli, SK.; Lam-Himlin, DM.; Heigh, RI. (2013). "Sarcina ventriculi of the stomach: a case report.". World J Gastroenterol 19 (14): 2282-5. doi:10.3748/wjg.v19.i14.2282. PMID 23599657.
- ↑ 3.0 3.1 Lam-Himlin, D.; Tsiatis, AC.; Montgomery, E.; Pai, RK.; Brown, JA.; Razavi, M.; Lamps, L.; Eshleman, JR. et al. (Nov 2011). "Sarcina organisms in the gastrointestinal tract: a clinicopathologic and molecular study.". Am J Surg Pathol 35 (11): 1700-5. doi:10.1097/PAS.0b013e31822911e6. PMID 21997690.