Difference between revisions of "Eosinophilic vacuolated tumour"

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'''High-grade oncocytic renal tumour''', abbreviated '''HOT''', is a [[kidney tumour]] type currently not recognized by the WHO classification as per the 2016 Blue Book.
'''High-grade oncocytic renal tumour''', abbreviated '''HOT''', is a [[kidney tumour]] type currently not recognized by the WHO classification as per the 2016 Blue Book.


It is a subset of what was previously lumped into ''[[renal hybrid oncocytic/chromophobe tumour]]''.
==General==
*Previously lumped into ''[[renal hybrid oncocytic/chromophobe tumour]]''.
 
==Microscopic==
Features:<ref name=pmid30232607>{{Cite journal  | last1 = He | first1 = H. | last2 = Trpkov | first2 = K. | last3 = Martinek | first3 = P. | last4 = Isikci | first4 = OT. | last5 = Maggi-Galuzzi | first5 = C. | last6 = Alaghehbandan | first6 = R. | last7 = Gill | first7 = AJ. | last8 = Tretiakova | first8 = M. | last9 = Lopez | first9 = JI. | title = "High-grade oncocytic renal tumor": morphologic, immunohistochemical, and molecular genetic study of 14 cases. | journal = Virchows Arch | volume = 473 | issue = 6 | pages = 725-738 | month = Dec | year = 2018 | doi = 10.1007/s00428-018-2456-4 | PMID = 30232607 }}</ref>
*Oncocytic cytoplasm with stippling.
*Prominent nucleoli.
 
DDx:
*[[Renal oncocytoma]].
*[[Renal hybrid oncocytic/chromophobe tumour]].
*[[Renal tumours with eosinophilic cytoplasm]].


==See also==
==See also==
*[[Kidney tumours]].
*[[Kidney tumours]].
==References==
{{Reflist|1}}


[[Category:Diagnosis]]
[[Category:Diagnosis]]

Revision as of 13:56, 6 February 2019

High-grade oncocytic renal tumour, abbreviated HOT, is a kidney tumour type currently not recognized by the WHO classification as per the 2016 Blue Book.

General

Microscopic

Features:[1]

  • Oncocytic cytoplasm with stippling.
  • Prominent nucleoli.

DDx:

See also

References

  1. He, H.; Trpkov, K.; Martinek, P.; Isikci, OT.; Maggi-Galuzzi, C.; Alaghehbandan, R.; Gill, AJ.; Tretiakova, M. et al. (Dec 2018). ""High-grade oncocytic renal tumor": morphologic, immunohistochemical, and molecular genetic study of 14 cases.". Virchows Arch 473 (6): 725-738. doi:10.1007/s00428-018-2456-4. PMID 30232607.