Difference between revisions of "Porocarcinoma"
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'''Porocarcinoma''' is a rare [[malignant]] [[skin tumour]] that has an aggressive behaviour.<ref name=pmid28721214>{{Cite journal | last1 = Salih | first1 = AM. | last2 = Kakamad | first2 = FH. | last3 = Baba | first3 = HO. | last4 = Salih | first4 = RQ. | last5 = Hawbash | first5 = MR. | last6 = Mohammed | first6 = SH. | last7 = Othman | first7 = S. | last8 = Saeed | first8 = YA. | last9 = Habibullah | first9 = IJ. | title = Porocarcinoma; presentation and management, a meta-analysis of 453 cases. | journal = Ann Med Surg (Lond) | volume = 20 | issue = | pages = 74-79 | month = Aug | year = 2017 | doi = 10.1016/j.amsu.2017.06.027 | PMID = 28721214 }}</ref> | '''Porocarcinoma''' is a rare [[malignant]] [[skin tumour]] that has an aggressive behaviour.<ref name=pmid28721214>{{Cite journal | last1 = Salih | first1 = AM. | last2 = Kakamad | first2 = FH. | last3 = Baba | first3 = HO. | last4 = Salih | first4 = RQ. | last5 = Hawbash | first5 = MR. | last6 = Mohammed | first6 = SH. | last7 = Othman | first7 = S. | last8 = Saeed | first8 = YA. | last9 = Habibullah | first9 = IJ. | title = Porocarcinoma; presentation and management, a meta-analysis of 453 cases. | journal = Ann Med Surg (Lond) | volume = 20 | issue = | pages = 74-79 | month = Aug | year = 2017 | doi = 10.1016/j.amsu.2017.06.027 | PMID = 28721214 }}</ref> | ||
It is also known as '''eccrine porocarcinoma''' | It is also known as '''eccrine porocarcinoma''' (abbreviated '''EPC''') and '''malignant eccrine poroma'''.<ref name=pmid20668633>{{Cite journal | last1 = Luz | first1 = Mde A. | last2 = Ogata | first2 = DC. | last3 = Montenegro | first3 = MF. | last4 = Biasi | first4 = LJ. | last5 = Ribeiro | first5 = LC. | title = Eccrine porocarcinoma (malignant eccrine poroma): a series of eight challenging cases. | journal = Clinics (Sao Paulo) | volume = 65 | issue = 7 | pages = 739-42 | month = Jul | year = 2010 | doi = 10.1590/S1807-59322010000700014 | PMID = 20668633 }}</ref> | ||
==General== | ==General== | ||
Revision as of 04:29, 6 June 2018
Porocarcinoma is a rare malignant skin tumour that has an aggressive behaviour.[1]
It is also known as eccrine porocarcinoma (abbreviated EPC) and malignant eccrine poroma.[2]
General
Clinical - based on meta-analysis of 453 cases:
- No predominance males versus females.
- Aggressive behaviour >30% of cases have metastases at presentation - typically to lymph nodes.
Treatment:
- Surgery,
Gross
- Mass or nodule - typically head and neck (40% of cases) or lower extremity (34% of cases).[1]
Microscopic
Features:
DDx:[3]
- Basal cell carcinoma.
- Squamous cell carcinoma.
- Pyogenic granuloma.
- Verruca vulgaris.
- Adenocarcinoma.
- Malignant melanoma - desmoplastic and nodular variants.
Images
See also
References
- ↑ 1.0 1.1 Salih, AM.; Kakamad, FH.; Baba, HO.; Salih, RQ.; Hawbash, MR.; Mohammed, SH.; Othman, S.; Saeed, YA. et al. (Aug 2017). "Porocarcinoma; presentation and management, a meta-analysis of 453 cases.". Ann Med Surg (Lond) 20: 74-79. doi:10.1016/j.amsu.2017.06.027. PMID 28721214.
- ↑ Luz, Mde A.; Ogata, DC.; Montenegro, MF.; Biasi, LJ.; Ribeiro, LC. (Jul 2010). "Eccrine porocarcinoma (malignant eccrine poroma): a series of eight challenging cases.". Clinics (Sao Paulo) 65 (7): 739-42. doi:10.1590/S1807-59322010000700014. PMID 20668633.
- ↑ 3.0 3.1 3.2 Abarzúa, Á.; Álvarez-Véliz, S.; Moll-Manzur, C.. "Concomitant poroma and porocarcinoma.". An Bras Dermatol 92 (4): 550-552. doi:10.1590/abd1806-4841.20175719. PMID 28954110.
- ↑ Riera-Leal, L.; Guevara-Gutiérrez, E.; Barrientos-García, JG.; Madrigal-Kasem, R.; Briseño-Rodríguez, G.; Tlacuilo-Parra, A. (2015). "Eccrine porocarcinoma: epidemiologic and histopathologic characteristics.". Int J Dermatol 54 (5): 580-6. doi:10.1111/ijd.12714. PMID 25515648.