Difference between revisions of "Ferruginous body"

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[[Image:Ferruginous bodies - BAL - r3 -- very high mag.jpg|right|thumb|300px|Ferruginous body in a BAL. (WC)]]
[[Image:Ferruginous bodies - BAL - r3 -- very high mag.jpg|right|thumb|300px|Ferruginous body in a BAL. (WC)]]
'''Ferruginous body''' is a histopathologic finding in [[lung pathology]] that strongly suggest exposure to asbestos.
'''Ferruginous body''' is a histopathologic finding in [[lung pathology]] that strongly suggests exposure to asbestos.


==General==
==General==
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==Microscopic==
==Microscopic==
Features:
Features:
*Segmented twirling baton with long slender fibre within.
*Segmented twirling baton-like structure (approximately 3-5 micrometres x 20-80 micrometres) with long slender fibre within.
*Black/brown crystal-like appearance.
*Black/brown crystal-like appearance.


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Image: Ferruginous bodies - BAL - r3 -- high mag.jpg | FB - high mag. (WC)
Image: Ferruginous bodies - BAL - r3 -- high mag.jpg | FB - high mag. (WC)
Image: Ferruginous bodies - BAL - r3 -- very high mag.jpg | FB - very high mag. (WC)
Image: Ferruginous bodies - BAL - r3 -- very high mag.jpg | FB - very high mag. (WC)
</gallery>
<gallery>
Image:Carcinoma asbestos body lung.jpg | Ferruginous body in carcinoma - cytology. (WC/Alex Brollo)
Image:Carcinoma asbestos body lung.jpg | Ferruginous body in carcinoma - cytology. (WC/Alex Brollo)
</gallery>
</gallery>


==Stains==
==Stains==
*Prussian blue +ve.
*[[Prussian blue stain]] +ve.
 
==Sign out==
<pre>
Comment:
No cell block is available for further work-up, e.g. iron staining.
 
The findings herein should be correlated with imaging and the clinical history.
Ferruginous bodies are associated asbestos exposure.
</pre>


==See also==
==See also==

Latest revision as of 17:46, 20 May 2018

Ferruginous body in a BAL. (WC)

Ferruginous body is a histopathologic finding in lung pathology that strongly suggests exposure to asbestos.

General

  • Uncommon finding.
  • Strongly suggestive of asbestos exposure.

Conditions associated with asbestos exposure (mnemonic PALM):[1]

Microscopic

Features:

  • Segmented twirling baton-like structure (approximately 3-5 micrometres x 20-80 micrometres) with long slender fibre within.
  • Black/brown crystal-like appearance.

DDx:

  • Dirt - especially on H&E.

Images

Cytology

Stains

Sign out

Comment:
No cell block is available for further work-up, e.g. iron staining.

The findings herein should be correlated with imaging and the clinical history. 
Ferruginous bodies are associated asbestos exposure.

See also

References

  1. Mitchell, Richard; Kumar, Vinay; Fausto, Nelson; Abbas, Abul K.; Aster, Jon (2011). Pocket Companion to Robbins & Cotran Pathologic Basis of Disease (8th ed.). Elsevier Saunders. pp. 375. ISBN 978-1416054542.