Difference between revisions of "Clear cell carcinoma"
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'''Clear cell carcinoma''', also '''clear cell adenocarcinoma''', is an aggressive uncommon malignancy seen in the [[gynecologic pathology|gynecologic tract]] | [[Image:Clear cell renal cell carcinoma - 2 -- very high mag.jpg|thumb|right|[[Clear cell renal cell carcinoma]], a common carcinoma with clear cells. [[H&E stain]].]] | ||
'''Clear cell carcinoma''', also '''clear cell adenocarcinoma''', is an aggressive uncommon [[malignancy]] seen in the [[gynecologic pathology|gynecologic tract]], [[skin]] and elsewhere. | |||
A broader [[differential diagnosis]] for clear cell tumours is found in the ''[[clear cell tumours]]'' article. | |||
==Ovary== | ==Gynecologic pathology== | ||
===Ovary=== | |||
:See ''[[Clear cell carcinoma of the ovary]]''. | :See ''[[Clear cell carcinoma of the ovary]]''. | ||
==Cervix== | ===Cervix=== | ||
:See ''[[Clear cell carcinoma of the uterine cervix]]''. | :See ''[[Clear cell carcinoma of the uterine cervix]]''. | ||
===Vagina=== | |||
:See ''[[Clear cell carcinoma of the vagina]]''. | |||
==Skin== | ==Skin== | ||
*[[Basal cell carcinoma|Clear cell basal cell carcinoma]].<ref>{{Cite journal | last1 = Sarma | first1 = DP. | last2 = Olson | first2 = D. | last3 = Olivella | first3 = J. | last4 = Harbert | first4 = T. | last5 = Wang | first5 = B. | last6 = Ortman | first6 = S. | title = Clear cell Basal cell carcinoma. | journal = Patholog Res Int | volume = 2011 | issue = | pages = 386921 | month = | year = 2011 | doi = 10.4061/2011/386921 | PMID = 21559201 }}</ref> | |||
*Others. | |||
==Clear cell variant of hepatocellular carcinoma== | ==Gastrointestinal pathology== | ||
===Clear cell variant of hepatocellular carcinoma=== | |||
{{Main|Hepatocellular carcinoma}} | {{Main|Hepatocellular carcinoma}} | ||
Morphologically, it may be similar to clear cell [[renal cell carcinoma]].<ref name=pmid10955454>{{Cite journal | last1 = Murakata | first1 = LA. | last2 = Ishak | first2 = KG. | last3 = Nzeako | first3 = UC. | title = Clear cell carcinoma of the liver: a comparative immunohistochemical study with renal clear cell carcinoma. | journal = Mod Pathol | volume = 13 | issue = 8 | pages = 874-81 | month = Aug | year = 2000 | doi = 10.1038/modpathol.3880156 | PMID = 10955454 }} | Morphologically, it may be similar to clear cell [[renal cell carcinoma]].<ref name=pmid10955454>{{Cite journal | last1 = Murakata | first1 = LA. | last2 = Ishak | first2 = KG. | last3 = Nzeako | first3 = UC. | title = Clear cell carcinoma of the liver: a comparative immunohistochemical study with renal clear cell carcinoma. | journal = Mod Pathol | volume = 13 | issue = 8 | pages = 874-81 | month = Aug | year = 2000 | doi = 10.1038/modpathol.3880156 | PMID = 10955454 }} | ||
</ref> | </ref> | ||
==Renal cell carcinoma== | ==Genitourinary pathology== | ||
===Urinary bladder=== | |||
:See ''[[Clear cell carcinoma of the urinary bladder]]''. | |||
===Urethra=== | |||
:See ''[[Clear cell adenocarcinoma of the urethra]]''. | |||
===Renal cell carcinoma=== | |||
These aren't always grouped with ''clear cell carcinoma''... but they have ''clear cell'' in the name: | |||
*[[Clear cell renal cell carcinoma]]. | *[[Clear cell renal cell carcinoma]]. | ||
*[[Clear cell papillary renal cell carcinoma]]. | *[[Clear cell papillary renal cell carcinoma]]. | ||
==Salivary gland== | Among others, clear cells may be seen in: | ||
*[[Xp11.2 translocation carcinoma]]. | |||
==Head and neck pathology== | |||
{{Main|Head and neck pathology}} | |||
*[[Hyalinizing clear cell carcinoma]]. | |||
===Salivary gland=== | |||
{{Main|Salivary gland}} | {{Main|Salivary gland}} | ||
*Rare. | *Rare. | ||
*Some consider | *Some consider clear cell carcinoma of the salivary gland a variant of ''[[epithelial-myoepithelial carcinoma]]''.<ref name=pmid12033955>{{Cite journal | last1 = Wang | first1 = B. | last2 = Brandwein | first2 = M. | last3 = Gordon | first3 = R. | last4 = Robinson | first4 = R. | last5 = Urken | first5 = M. | last6 = Zarbo | first6 = RJ. | title = Primary salivary clear cell tumors--a diagnostic approach: a clinicopathologic and immunohistochemical study of 20 patients with clear cell carcinoma, clear cell myoepithelial carcinoma, and epithelial-myoepithelial carcinoma. | journal = Arch Pathol Lab Med | volume = 126 | issue = 6 | pages = 676-85 | month = Jun | year = 2002 | doi = 10.1043/0003-9985(2002)1260676:PSCCTA2.0.CO;2 | PMID = 12033955 }}</ref> | ||
==See also== | ==See also== | ||
*[[Adenocarcinoma]]. | |||
*[[Gynecologic pathology]]. | *[[Gynecologic pathology]]. | ||
*[[Clear cell tumours]]. | *[[Clear cell tumours]]. | ||
Latest revision as of 17:19, 9 January 2017
Clear cell carcinoma, also clear cell adenocarcinoma, is an aggressive uncommon malignancy seen in the gynecologic tract, skin and elsewhere.
A broader differential diagnosis for clear cell tumours is found in the clear cell tumours article.
Gynecologic pathology
Ovary
Cervix
Vagina
Skin
- Clear cell basal cell carcinoma.[1]
- Others.
Gastrointestinal pathology
Clear cell variant of hepatocellular carcinoma
Main article: Hepatocellular carcinoma
Morphologically, it may be similar to clear cell renal cell carcinoma.[2]
Genitourinary pathology
Urinary bladder
Urethra
Renal cell carcinoma
These aren't always grouped with clear cell carcinoma... but they have clear cell in the name:
Among others, clear cells may be seen in:
Head and neck pathology
Main article: Head and neck pathology
Salivary gland
Main article: Salivary gland
- Rare.
- Some consider clear cell carcinoma of the salivary gland a variant of epithelial-myoepithelial carcinoma.[3]
See also
References
- ↑ Sarma, DP.; Olson, D.; Olivella, J.; Harbert, T.; Wang, B.; Ortman, S. (2011). "Clear cell Basal cell carcinoma.". Patholog Res Int 2011: 386921. doi:10.4061/2011/386921. PMID 21559201.
- ↑ Murakata, LA.; Ishak, KG.; Nzeako, UC. (Aug 2000). "Clear cell carcinoma of the liver: a comparative immunohistochemical study with renal clear cell carcinoma.". Mod Pathol 13 (8): 874-81. doi:10.1038/modpathol.3880156. PMID 10955454.
- ↑ Wang, B.; Brandwein, M.; Gordon, R.; Robinson, R.; Urken, M.; Zarbo, RJ. (Jun 2002). "Primary salivary clear cell tumors--a diagnostic approach: a clinicopathologic and immunohistochemical study of 20 patients with clear cell carcinoma, clear cell myoepithelial carcinoma, and epithelial-myoepithelial carcinoma.". Arch Pathol Lab Med 126 (6): 676-85. doi:10.1043/0003-9985(2002)1260676:PSCCTA2.0.CO;2. PMID 12033955.