Difference between revisions of "Fibrous pseudotumour of the paratesticular region"

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'''Fibrous pseudotumour of the paratesticular region''' is a very rare tumour of the para[[testicle|testicular]] region.<ref name=pmid24459661>{{Cite journal  | last1 = Bharti | first1 = JN. | last2 = Dey | first2 = B. | last3 = Mittal | first3 = A. | last4 = Arora | first4 = P. | title = A case of fibrous pseudotumor of the paratesticular region. | journal = World J Mens Health | volume = 31 | issue = 3 | pages = 262-4 | month = Dec | year = 2013 | doi = 10.5534/wjmh.2013.31.3.262 | PMID = 24459661 }}</ref>
{{ Infobox diagnosis
| Name      = {{PAGENAME}}
| Image      = Paratesticular fibrous pseudotumour -- intermed mag.jpg
| Width      =
| Caption    = Paratesticular fibrous pseudotumour. [[H&E stain]].
| Synonyms  =
| Micro      = [[spindle cells]] with moderate eosinophilic cytoplasm and indistinct cellular borders, no significant nuclear atypia
| Subtypes  =
| LMDDx      = [[leiomyoma]], [[fibroma]] of the tunics, [[fibromatosis]], [[solitary fibrous tumour]], [[inflammatory pseudotumour]]
| Stains    =
| IHC        = CD34 +ve/-ve, S-100 -ve, desmin -ve, [[keratins]] -ve
| EM        =
| Molecular  =
| IF        =
| Gross      =
| Grossing  =
| Site      = [[paratesticular region]]
| Assdx      =
| Syndromes  =
| Clinicalhx =
| Signs      =
| Symptoms  =
| Prevalence = very rare
| Bloodwork  =
| Rads      =
| Endoscopy  =
| Prognosis  = good
| Other      =
| ClinDDx    = other paratesticular lesions and testicular lesions
| Tx        = surgical excision to exclude serious pathology
}}
'''Fibrous pseudotumour of the paratesticular region''' is a very rare tumour of the [[paratesticular region]].<ref name=pmid24459661>{{Cite journal  | last1 = Bharti | first1 = JN. | last2 = Dey | first2 = B. | last3 = Mittal | first3 = A. | last4 = Arora | first4 = P. | title = A case of fibrous pseudotumor of the paratesticular region. | journal = World J Mens Health | volume = 31 | issue = 3 | pages = 262-4 | month = Dec | year = 2013 | doi = 10.5534/wjmh.2013.31.3.262 | PMID = 24459661 }}</ref>


==General==
==General==
*May be associated with the [[epididymis]] or tunica vaginalis of the [[testis]].<ref name=pmid24627288>{{Cite journal  | last1 = Zhang | first1 = Z. | last2 = Yang | first2 = J. | last3 = Li | first3 = M. | last4 = Cai | first4 = W. | last5 = Liu | first5 = Q. | last6 = Wang | first6 = T. | last7 = Guo | first7 = X. | last8 = Wang | first8 = S. | last9 = Liu | first9 = J. | title = Paratesticular fibrous pseudotumor: a report of five cases and literature review. | journal = Front Med | volume =  | issue =  | pages =  | month = Mar | year = 2014 | doi = 10.1007/s11684-014-0325-3 | PMID = 24627288 }}</ref>
*May be associated with the [[epididymis]] or tunica vaginalis of the [[testis]].<ref name=pmid24627288>{{Cite journal  | last1 = Zhang | first1 = Z. | last2 = Yang | first2 = J. | last3 = Li | first3 = M. | last4 = Cai | first4 = W. | last5 = Liu | first5 = Q. | last6 = Wang | first6 = T. | last7 = Guo | first7 = X. | last8 = Wang | first8 = S. | last9 = Liu | first9 = J. | title = Paratesticular fibrous pseudotumor: a report of five cases and literature review. | journal = Front Med | volume =  | issue =  | pages =  | month = Mar | year = 2014 | doi = 10.1007/s11684-014-0325-3 | PMID = 24627288 }}</ref>
**Uncommonly associated with the epididymis (<10% of tumours<ref name=pmid11018636>{{Cite journal  | last1 = Tobias-machado | first1 = M. | last2 = Corrêa Lopes Neto | first2 = A. | last3 = Heloisa Simardi | first3 = L. | last4 = Borrelli | first4 = M. | last5 = Wroclawski | first5 = ER. | title = Fibrous pseudotumor of tunica vaginalis and epididymis. | journal = Urology | volume = 56 | issue = 4 | pages = 670-2 | month = Oct | year = 2000 | doi =  | PMID = 11018636 }}</ref>).


==Microscopic==
==Microscopic==
Features:<ref name=pmid24627288/>
Features:<ref name=pmid24627288/>
*Spindle cells with  
*Spindle cells with:
**Moderate eosinophilic cytoplasm.
**Moderate eosinophilic cytoplasm.
**Indistinct cellular borders.
**Indistinct cellular borders.
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*[[Solitary fibrous tumour]].
*[[Solitary fibrous tumour]].
*[[Inflammatory pseudotumour]].
*[[Inflammatory pseudotumour]].
===Images===
<gallery>
Image: Paratesticular fibrous pseudotumour -- very low mag.jpg | PFP - very low mag.
Image: Paratesticular fibrous pseudotumour -- low mag.jpg | PFP - low mag.
Image: Paratesticular fibrous pseudotumour -- intermed mag.jpg | PFP - intermed. mag.
Image: Paratesticular fibrous pseudotumour - alt -- intermed mag.jpg | PFP - intermed. mag.
Image: Paratesticular fibrous pseudotumour -- high mag.jpg | PFP - high mag.
</gallery>


==IHC==
==IHC==
Features:
Features:<ref name=pmid9060599>{{Cite journal  | last1 = Jones | first1 = MA. | last2 = Young | first2 = RH. | last3 = Scully | first3 = RE. | title = Benign fibromatous tumors of the testis and paratesticular region: a report of 9 cases with a proposed classification of fibromatous tumors and tumor-like lesions. | journal = Am J Surg Pathol | volume = 21 | issue = 3 | pages = 296-305 | month = Mar | year = 1997 | doi =  | PMID = 9060599 }}</ref>
*CD34 -ve.
*CD34 +ve/-ve.
*S-100 -ve.
*Desmin -ve.
*Keratin -ve.


==See also==
==See also==

Latest revision as of 03:10, 2 August 2016

Fibrous pseudotumour of the paratesticular region
Diagnosis in short

Paratesticular fibrous pseudotumour. H&E stain.
LM spindle cells with moderate eosinophilic cytoplasm and indistinct cellular borders, no significant nuclear atypia
LM DDx leiomyoma, fibroma of the tunics, fibromatosis, solitary fibrous tumour, inflammatory pseudotumour
IHC CD34 +ve/-ve, S-100 -ve, desmin -ve, keratins -ve
Site paratesticular region
Prevalence very rare
Prognosis good
Clin. DDx other paratesticular lesions and testicular lesions
Treatment surgical excision to exclude serious pathology

Fibrous pseudotumour of the paratesticular region is a very rare tumour of the paratesticular region.[1]

General

  • May be associated with the epididymis or tunica vaginalis of the testis.[2]
    • Uncommonly associated with the epididymis (<10% of tumours[3]).

Microscopic

Features:[2]

  • Spindle cells with:
    • Moderate eosinophilic cytoplasm.
    • Indistinct cellular borders.

DDx:[2]

Images

  • PFP - very low mag.

  • PFP - low mag.

  • PFP - intermed. mag.

  • PFP - intermed. mag.

  • PFP - high mag.

IHC

Features:[4]

  • CD34 +ve/-ve.
  • S-100 -ve.
  • Desmin -ve.
  • Keratin -ve.

See also

References

  1. ↑ Bharti, JN.; Dey, B.; Mittal, A.; Arora, P. (Dec 2013). "A case of fibrous pseudotumor of the paratesticular region.". World J Mens Health 31 (3): 262-4. doi:10.5534/wjmh.2013.31.3.262. PMID 24459661.
  2. ↑ 2.0 2.1 2.2 Zhang, Z.; Yang, J.; Li, M.; Cai, W.; Liu, Q.; Wang, T.; Guo, X.; Wang, S. et al. (Mar 2014). "Paratesticular fibrous pseudotumor: a report of five cases and literature review.". Front Med. doi:10.1007/s11684-014-0325-3. PMID 24627288.
  3. ↑ Tobias-machado, M.; Corrêa Lopes Neto, A.; Heloisa Simardi, L.; Borrelli, M.; Wroclawski, ER. (Oct 2000). "Fibrous pseudotumor of tunica vaginalis and epididymis.". Urology 56 (4): 670-2. PMID 11018636.
  4. ↑ Jones, MA.; Young, RH.; Scully, RE. (Mar 1997). "Benign fibromatous tumors of the testis and paratesticular region: a report of 9 cases with a proposed classification of fibromatous tumors and tumor-like lesions.". Am J Surg Pathol 21 (3): 296-305. PMID 9060599.
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