Difference between revisions of "Gastric ulcer"
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*[[Peptic ulcer disease]]. | *[[Peptic ulcer disease]]. | ||
**[[Helicobacter gastritis]]. | **[[Helicobacter gastritis]]. | ||
*[[Syphilis]].<ref name=pmid8343046>{{Cite journal | last1 = Fyfe | first1 = B. | last2 = Poppiti | first2 = RJ. | last3 = Lubin | first3 = J. | last4 = Robinson | first4 = MJ. | title = Gastric syphilis. Primary diagnosis by gastric biopsy: report of four cases. | journal = Arch Pathol Lab Med | volume = 117 | issue = 8 | pages = 820-3 | month = Aug | year = 1993 | doi = | PMID = 8343046 }}</ref> | |||
*Other causes. | |||
==Gross== | ==Gross== | ||
Revision as of 02:39, 13 February 2016
Gastric ulcer, also stomach ulcer, is pathology of the stomach that is evident grossly. It can be benign or malignant.
General
- May be benign or malignant.
Causes:
- Gastric carcinoma.
- Peptic ulcer disease.
- Syphilis.[1]
- Other causes.
Gross
- Heaped (raised) edges - suggestive of cancer.
- Punched-out appearance with flat edges - suggestive of benign.
Notes:
- Classical teaching is to biopsied the ulcer edge, as the dictum is: the cancer is there; this dictum may not be true.[2]
Images
Malignant ulcer of the stomach. (WC)
Microscopic
Features:
- Loss of the (gastric) epithelium.
- Vital reaction.
- Marked (acute) inflammation.
- Fibrin.
Images
SU - low mag. (WC)
SU - intermed. mag. (WC)
Sign out
Compatible with benign
A. STOMACH, BIOPSY: - GASTRIC ANTRAL-TYPE MUCOSA WITH EDEMA, FOCALLY PROMINENT SMOOTH MUSCLE, ACTIVATED FIBROBLASTS, A MILD INCREASE OF EOSINOPHILS, AND FIBRIN -- COMPATIBLE WITH NEARBY ULCER. - NEGATIVE FOR HELICOBACTOR-LIKE ORGANISMS. - NEGATIVE FOR INTESTINAL METAPLASIA. - NEGATIVE FOR DYSPLASIA AND NEGATIVE FOR MALIGNANCY.
See also
References
- ↑ Fyfe, B.; Poppiti, RJ.; Lubin, J.; Robinson, MJ. (Aug 1993). "Gastric syphilis. Primary diagnosis by gastric biopsy: report of four cases.". Arch Pathol Lab Med 117 (8): 820-3. PMID 8343046.
- ↑ Lv, SX.; Gan, JH.; Ma, XG.; Wang, CC.; Chen, HM.; Luo, EP.; Huang, XP.; Wu, SH. et al. (May 2012). "Biopsy from the base and edge of gastric ulcer healing or complete healing may lead to detection of gastric cancer earlier: an 8 years endoscopic follow-up study.". Hepatogastroenterology 59 (115): 947-50. doi:10.5754/hge10692. PMID 22469743.