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===Clinical history===
===Clinical history===
55 year old woman, renal mass.
45 year old woman, renal mass.
===Primary image===
===Primary image===
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{{hidden|More history|<center>Sister had a renal tumour. Biopsy diagnosis was ''[[clear cell renal cell carcinoma]]''.</center>}}
{{hidden|More history|<center>Sister had a renal tumour. Biopsy diagnosis was ''[[clear cell renal cell carcinoma]]''.</center>}}
====Ask a friend====
====Ask a friend====
{{hidden|Ask a friend|<center>I wonder if this is genetic. Our lab doesn't have the one stain I think that would be really useful here.</center>}}
{{hidden|Ask a friend|<center>There is one immunostain I think would be really useful here. If I am right, this case may have the [[chromosomal translocation]] seen in [[alveolar soft part sarcoma]].</center>}}
====Stains====
====Stains====
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| warthinstarry=
| warthinstarry=
}}
}}
====IHC====
====IHC====
{{Case IHC
{{Case IHC
| blank=Dr T would ask why!
| blank= Dr Torres would ask why!
| ae1ae3=
| ae1ae3=
| a1at=
| a1at=
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| afp=
| afp=
| alk1=
| alk1=
| amacr=
| b2microgl=
| b2microgl=
| b723=
| b723=
| bcatenin=
| bcl2=
| bcl2=
| bcl6=
| bcl6=
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| calponin=
| calponin=
| calretinin=
| calretinin=
| cd10= '''POSITIVE'''
| cd10= '''POSITIVE'''
| cd117=
| cd117=
| cd15=
| cd15=
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| cd56=
| cd56=
| cd68=
| cd68=
| cd7= '''NEGATIVE'''
| cd7=
| cd79a=
| cd79a=
| cd8=
| cd8=
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| ck20=
| ck20=
| ck34be12=
| ck34be12=
| ck7=
| ck7= '''NEGATIVE'''
| cmv=
| cmv=
| cmyc=
| cmyc=
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| lh=
| lh=
| lysozyme=
| lysozyme=
| melanina= '''NEGATIVE'''
| melanina= '''NEGATIVE'''
| mitf=
| myleoperox=
| myleoperox=
| myod1=
| myod1=
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| myog=
| myog=
| nse=
| nse=
| p16=
| p53=
| p53=
| p63=
| p63=
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| psa=
| psa=
| s100=
| s100=
| sma=
| sma=
| somatsat=
| somatsat=
| synapto=
| synapto=
| tdt=
| tdt=
| tfe3= '''POSITIVE'''
| thyrogl=
| thyrogl=
| toxopl=
| toxopl=
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| uchl1=
| uchl1=
| ulexeurope=
| ulexeurope=
| vim= '''POSITIVE'''
| vim= '''POSITIVE'''
| vip=
| vip=
| vzv=
| vzv=
| wt1=
}}
====Chromosomal translocations====
{{Case Translocations
| blank=Dr Torres would ask why!
| t1_13=
| t11_14=
| t11_22dsrct=
| t11_22ews=
| t12_15=
| t12_16afh=
| t12_16liposar=
| t12_22=
| t14_18=
| t15_17=
| t16_21=
| t17_22=
| t2_13=
| t21_22=
| t8_14=
| t9_22=
| t9_22=
| tx_1= '''NOT IDENTIFIED'''
| tx_17= '''PRESENT'''
| tx_18=
}}
}}
===Diagnosis===
===Diagnosis===
{{hidden|Diagnosis|<center>[[Renal tumour with Xp11.2 translocation]].</center>}}
These tumours are in the [[MiT family translocation renal cell carcinoma]]. They are a relatively common form of renal cell carcinoma in children; however, they are uncommon in adults. In adults they tend to have a poor prognosis.}}
<br>
===Other cases===
{{Cases navigation|state=collapsed}}
__NOTOC__
__NOTOC__
[[Category:Cases]]
[[Category:Cases]]
[[Category:Cases in genitourinary pathology]]
[[Category:Cases in molecular pathology]]
[[Category:Cases difficulty 4]]
[[Category:Cases in genitourinary pathology - senior]]
[[Category:Cases in molecular pathology - senior]]
Comment:
These tumours are in the MiT family translocation renal cell carcinoma. They are a relatively common form of renal cell carcinoma in children; however, they are uncommon in adults. In adults they tend to have a poor prognosis.
