Created page with "===Provided clinical history=== 45 year old woman, with intractable uterine bleeding unresponsive to hormone therapy. Mass lesion in the myometrium ===Site=== Uterus- myomet..."
{{hidden|More history|<center>Patient had received lysteda for control of bleeding </center>}}
{{hidden|More history|<center>Patient had received lysteda for control of bleeding.</center>}}
====Ask a colleague====
====Ask a colleague====
{{hidden|Ask a colleague|<center>COLLEAGUE'S ADVICE HERE</center>}}
{{hidden|Ask a colleague|<center>Did you check the history? I wonder whether this could be drug effect.</center>}}
====Stains====
====Stains====
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===Diagnosis===
===Diagnosis===
{{hidden|Diagnosis|<center>LEIOMYOMA WITH TRANEXAMIC ACID ASSOCIATED MICROINFARCTION. This smooth muscle tumor depicts no atypia. When in this situation it is prudent to request detailed clinical history. Clinicians often do not inform of all agents given to patients to control uterine bleeding. {{Cite journal | last1 = Ip | first1 = PP. | last2 = Lam | first2 = KW. | last3 = Cheung | first3 = CL. | last4 = Yeung | first4 = MC. | last5 = Pun | first5 = TC. | last6 = Chan | first6 = QK. | last7 = Cheung | first7 = AN. | title = Tranexamic acid-associated necrosis and intralesional thrombosis of uterine leiomyomas: a clinicopathologic study of 147 cases emphasizing the importance of drug-induced necrosis and early infarcts in leiomyomas. | journal = Am J Surg Pathol | volume = 31 | issue = 8 | pages = 1215-24 | month = Aug | year = 2007 | doi = 10.1097/PAS.0b013e318032125e | PMID = 17667546 }}</center>}}
{{hidden|Diagnosis|<center>[[uterine leiomyoma|LEIOMYOMA]] WITH TRANEXAMIC ACID ASSOCIATED MICROINFARCTION</center><br>
This smooth muscle tumor depicts no atypia. When in this situation it is prudent to request detailed [[clinical history]]. Clinicians often do not inform of all agents given to patients to control uterine bleeding.<ref name=pmid17667546>{{Cite journal | last1 = Ip | first1 = PP. | last2 = Lam | first2 = KW. | last3 = Cheung | first3 = CL. | last4 = Yeung | first4 = MC. | last5 = Pun | first5 = TC. | last6 = Chan | first6 = QK. | last7 = Cheung | first7 = AN. | title = Tranexamic acid-associated necrosis and intralesional thrombosis of uterine leiomyomas: a clinicopathologic study of 147 cases emphasizing the importance of drug-induced necrosis and early infarcts in leiomyomas. | journal = Am J Surg Pathol | volume = 31 | issue = 8 | pages = 1215-24 | month = Aug | year = 2007 | doi = 10.1097/PAS.0b013e318032125e | PMID = 17667546 }}</ref>
===References===
{{Reflist|1}}
}}
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===Other cases===
===Other cases===
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[[Category:Cases]]
[[Category:Cases]]
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[[Category:Cases in gynecologic pathology]]
[[Category:Cases in gynecologic pathology]]
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[[Category:Cases in gynecologic pathology - fellow and expert]]
[[Category:Cases difficulty 7]] <!-- difficulty 1-7 -- should roughly correspond to the PGY level -->
[[Category:Cases difficulty 7]] <!-- difficulty 1-7 -- should roughly correspond to the PGY level -->
Latest revision as of 03:17, 27 September 2015
Provided clinical history
45 year old woman, with intractable uterine bleeding unresponsive to hormone therapy. Mass lesion in the myometrium
LEIOMYOMA WITH TRANEXAMIC ACID ASSOCIATED MICROINFARCTION
This smooth muscle tumor depicts no atypia. When in this situation it is prudent to request detailed clinical history. Clinicians often do not inform of all agents given to patients to control uterine bleeding.[1]
References
↑Ip, PP.; Lam, KW.; Cheung, CL.; Yeung, MC.; Pun, TC.; Chan, QK.; Cheung, AN. (Aug 2007). "Tranexamic acid-associated necrosis and intralesional thrombosis of uterine leiomyomas: a clinicopathologic study of 147 cases emphasizing the importance of drug-induced necrosis and early infarcts in leiomyomas.". Am J Surg Pathol31 (8): 1215-24. doi:10.1097/PAS.0b013e318032125e. PMID17667546.
