Difference between revisions of "Sarcomatoid carcinoma of the prostate"
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'''Sarcomatoid prostate carcinoma''' is a rare subtype of [[prostatic carcinoma | '''Sarcomatoid prostate carcinoma''' is a rare subtype of [[prostatic carcinoma]]. | ||
==General== | ==General== | ||
*Rare. | *Rare.<ref name=pmid17001164>{{Cite journal | last1 = Hansel | first1 = DE. | last2 = Epstein | first2 = JI. | title = Sarcomatoid carcinoma of the prostate: a study of 42 cases. | journal = Am J Surg Pathol | volume = 30 | issue = 10 | pages = 1316-21 | month = Oct | year = 2006 | doi = 10.1097/01.pas.0000209838.92842.bf | PMID = 17001164 }}</ref> | ||
*Poor prognosis - estimated 20% mortality at one year.<ref name=pmid17001164/> | |||
==Microscopic== | ==Microscopic== | ||
Revision as of 01:43, 17 July 2015
Sarcomatoid prostate carcinoma is a rare subtype of prostatic carcinoma.
General
Microscopic
Features:[2]
- Biphasic tumour:
- Spindle cells (sarcomatous component).
- May include components of: osteosarcoma, chondrosarcoma and/or rhabdomyosarcoma.
- Glandular component (like conventional prostate carcinoma).
- Spindle cells (sarcomatous component).
IHC
Features - typical:[2]
- PSA +ve.
- Keratin +ve.
See also
References
- ↑ 1.0 1.1 Hansel, DE.; Epstein, JI. (Oct 2006). "Sarcomatoid carcinoma of the prostate: a study of 42 cases.". Am J Surg Pathol 30 (10): 1316-21. doi:10.1097/01.pas.0000209838.92842.bf. PMID 17001164.
- ↑ 2.0 2.1 Zhou, Ming; Magi-Galluzzi, Cristina (2006). Genitourinary Pathology: A Volume in Foundations in Diagnostic Pathology Series (1st ed.). Churchill Livingstone. pp. 77 & 80. ISBN 978-0443066771.