Difference between revisions of "Sarcomatoid urothelial carcinoma"
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==General== | ==General== | ||
*Rare.<ref name=pmid26068625/> | *Rare.<ref name=pmid26068625/> | ||
*Aggressive >55% dead within one year of presentation.<ref name=pmid26068625/> | *Aggressive >55% dead within one year of presentation.<ref name=pmid26068625/> | ||
==Gross== | |||
*Tumour of bladder, [[ureter]]<ref name=pmid24902363>{{Cite journal | last1 = Nicolas | first1 = MM. | last2 = Nazarullah | first2 = A. | last3 = Guo | first3 = CC. | title = Sarcomatoid urothelial carcinoma with chondrosarcomatous differentiation of the ureter: a case report. | journal = Anal Quant Cytopathol Histpathol | volume = 36 | issue = 2 | pages = 111-6 | month = Apr | year = 2014 | doi = | PMID = 24902363 }}</ref> or renal pelvis.<ref name=pmid25120689>{{Cite journal | last1 = Tian | first1 = X. | last2 = Zhao | first2 = J. | last3 = Wang | first3 = Y. | last4 = Xing | first4 = N. | title = Sarcomatoid carcinoma of the renal pelvis: A case report. | journal = Oncol Lett | volume = 8 | issue = 3 | pages = 1208-1210 | month = Sep | year = 2014 | doi = 10.3892/ol.2014.2240 | PMID = 25120689 }}</ref> | |||
==Microscopic== | ==Microscopic== | ||
Revision as of 06:18, 19 June 2015
Sarcomatoid urothelial carcinoma (abbreviated sarcomatoid UC), also sarcomatoid urothelial cell carcinoma (abbreviated sarcomatoid UCC), is a rare variant of urothelial carcinoma.[1]
General
Gross
Microscopic
Features:
- Urothelial carcinoma (classic or recognizable variant).
- Sarcomatoid differentiation - typically (undifferentiated) spindle cells.
- Approximately have 10% of heterologous elements,[1] e.g. chondrosarcomatous differentiation, osteosarcomatous differentiation.
DDx:
- Sarcoma - esp. those arising from the retroperitoneum.
Images
Sarcomatoid UCC - low mag.
Sarcomatoid UCC - intermed. mag.
Sarcomatoid UCC - high mag.
See also
References
- ↑ 1.0 1.1 1.2 1.3 Fatima, N.; Canter, DJ.; Carthon, BC.; Kucuk, O.; Master, VA.; Nieh, PT.; Ogan, K.; Osunkoya, AO. (Jun 2015). "Sarcomatoid urothelial carcinoma of the bladder: a contemporary clinicopathologic analysis of 37 cases.". Can J Urol 22 (3): 7783-7. PMID 26068625.
- ↑ Nicolas, MM.; Nazarullah, A.; Guo, CC. (Apr 2014). "Sarcomatoid urothelial carcinoma with chondrosarcomatous differentiation of the ureter: a case report.". Anal Quant Cytopathol Histpathol 36 (2): 111-6. PMID 24902363.
- ↑ Tian, X.; Zhao, J.; Wang, Y.; Xing, N. (Sep 2014). "Sarcomatoid carcinoma of the renal pelvis: A case report.". Oncol Lett 8 (3): 1208-1210. doi:10.3892/ol.2014.2240. PMID 25120689.