Difference between revisions of "Bullous diseases"
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==See also== | ==See also== | ||
*[[Non-malignant skin disease]] | *[[Non-malignant skin disease]]. | ||
*[[Dermatopathology introduction]] | *[[Dermatopathology introduction]]. | ||
==References== | ==References== | ||
Revision as of 17:11, 12 May 2010
Bullous disease happens. Dermatopathologists help diagnose it.
DDx of bullous disease:[1]
- Bullous pemphigoid.
- Pemphigus vulgaris.
- Porphyria cutanea tarda.
- Dermatitis herpetiformis.
- Epidermolysis bullosa.
Bullous pemphigoid
Epidemiology
- Old people (60-80 year olds).
Pemphigus vulgaris
Classic presentation
- Mouth lesions.
- Non-pruritic.
Treatment
- Prednisone then steroid sparing agent.
Epidemiology
- Assoc. with thymoma, myasthenia gravis, malignancy & D-penicillamine (for Wilson's disease).
- Middle age.
DDx: Hailey-Hailey disease.
Dermatitis herpetiformis
Assoc. with celiac sprue.
Porphyria cutanea tarda
Etiology
- Genetic, autosomal dominant.
Appearance
- Vesicles/bullae in photoexposed areas subjected to trauma.
Associations
Medications/Substances:
Non-infection chronic conditions:
- DM.
Infections:
Treatment
- d/c aggravating substances (listed above), phlebotomy, hydroxychloroquine if phlebotomy contraindicated.
Epidermolysis bullosa
- Inherited, bullae & erosions from slight mechanical trauma.
See also
References
- ↑ TN07 D21-3.