Difference between revisions of "Squamous dysplasia of the head and neck"

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*Moderate dysplasia.
*Moderate dysplasia.
*Severe dysplasia.
*Severe dysplasia.
*Carcinoma in situ.
====Ljubljana system====
As per ''Gale et al.'':<ref name=pmid24689850>{{Cite journal  | last1 = Gale | first1 = N. | last2 = Blagus | first2 = R. | last3 = El-Mofty | first3 = SK. | last4 = Helliwell | first4 = T. | last5 = Prasad | first5 = ML. | last6 = Sandison | first6 = A. | last7 = Volavšek | first7 = M. | last8 = Wenig | first8 = BM. | last9 = Zidar | first9 = N. | title = Evaluation of a new grading system for laryngeal squamous intraepithelial lesions-a proposed unified classification. | journal = Histopathology | volume = 65 | issue = 4 | pages = 456-64 | month = Oct | year = 2014 | doi = 10.1111/his.12427 | PMID = 24689850 }}</ref>
*Low-grade SIL.
*High-grade SIL.
*Carcinoma in situ.
*Carcinoma in situ.


Revision as of 01:01, 5 December 2014

Squamous dysplasia of the head and neck, often squamous dysplasia, is a precursor to head and neck squamous cell carcinoma.

General

Gross

Features:[1]

Microscopic

Features:

  • Basal nuclear atypia - may be mild.
  • Lack of maturation to the surface.
  • +/-Parakeratosis.

DDx:

Grading

  • Numerous grading systems exist.[2]

WHO system

The 2005 "blue book" system - as summarized by Gale et al.:[2]

  • Mild dysplasia.
  • Moderate dysplasia.
  • Severe dysplasia.
  • Carcinoma in situ.

Ljubljana system

As per Gale et al.:[3]

  • Low-grade SIL.
  • High-grade SIL.
  • Carcinoma in situ.

Images

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PHARYNGEAL WALL, POSTERIOR, BIOPSY:
- SQUAMOUS MUCOSA WITH MILD SQUAMOUS DYSPLASIA.
- NEGATIVE FOR MALIGNANCY.

See also

References

  1. ↑ 1.0 1.1 Eversole, LR. (Mar 2009). "Dysplasia of the upper aerodigestive tract squamous epithelium.". Head Neck Pathol 3 (1): 63-8. doi:10.1007/s12105-009-0103-8. PMID 20596993.
  2. ↑ 2.0 2.1 Gale, N.; Zidar, N.; Poljak, M.; Cardesa, A. (Mar 2014). "Current views and perspectives on classification of squamous intraepithelial lesions of the head and neck.". Head Neck Pathol 8 (1): 16-23. doi:10.1007/s12105-014-0530-z. PMID 24595419.
  3. ↑ Gale, N.; Blagus, R.; El-Mofty, SK.; Helliwell, T.; Prasad, ML.; Sandison, A.; Volavšek, M.; Wenig, BM. et al. (Oct 2014). "Evaluation of a new grading system for laryngeal squamous intraepithelial lesions-a proposed unified classification.". Histopathology 65 (4): 456-64. doi:10.1111/his.12427. PMID 24689850.
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