Difference between revisions of "Succinate dehydrogenase"

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[[Image:Denervation atrophy - sdh - very high mag.jpg|thumb|right|SDH immunostain in a muscle biopsy with [[denervation atrophy]].]]
[[Image:Denervation atrophy - sdh - very high mag.jpg|thumb|right|SDH immunostain in a muscle biopsy with denervation atrophy.]]
'''Succinate dehydrogenase''', abbreviated '''SDH''', is an enzyme complex in the citric acid cycle and electron transport chain.  It is localized to the mitochondria.
'''Succinate dehydrogenase''', abbreviated '''SDH''', is an enzyme complex in the citric acid cycle and electron transport chain.  It is localized to the mitochondria.



Revision as of 05:53, 27 October 2014

SDH immunostain in a muscle biopsy with denervation atrophy.

Succinate dehydrogenase, abbreviated SDH, is an enzyme complex in the citric acid cycle and electron transport chain. It is localized to the mitochondria.

Mutation-associated with pathology:

See also

References

  1. 1.0 1.1 Vicha, A.; Taieb, D.; Pacak, K. (Jun 2014). "Current views on cell metabolism in SDHx-related pheochromocytoma and paraganglioma.". Endocr Relat Cancer 21 (3): R261-77. doi:10.1530/ERC-13-0398. PMID 24500761.
  2. Ricketts, CJ.; Shuch, B.; Vocke, CD.; Metwalli, AR.; Bratslavsky, G.; Middelton, L.; Yang, Y.; Wei, MH. et al. (Dec 2012). "Succinate dehydrogenase kidney cancer: an aggressive example of the Warburg effect in cancer.". J Urol 188 (6): 2063-71. doi:10.1016/j.juro.2012.08.030. PMID 23083876.