Difference between revisions of "Pediatric pathology"
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==Hypoxic-ischemic encephalopathy== | ==Hypoxic-ischemic encephalopathy== | ||
{{Main|Neuropathology}} | {{Main|Neuropathology}} | ||
*Abbreviated ''HIE''. | |||
*Autopsy adds some information. | *Autopsy adds some information. | ||
*Two-tone liver - suggests prior injury.<ref name=pmid15957995>{{cite journal |author=Elder DE, Zuccollo JM, Stanley TV |title=Neonatal death after hypoxic ischaemic encephalopathy: does a postmortem add to the final diagnoses? |journal=BJOG |volume=112 |issue=7 |pages=935–40 |year=2005 |month=July |pmid=15957995 |doi=10.1111/j.1471-0528.2005.00608.x |url=}}</ref> | *Two-tone liver - suggests prior injury.<ref name=pmid15957995>{{cite journal |author=Elder DE, Zuccollo JM, Stanley TV |title=Neonatal death after hypoxic ischaemic encephalopathy: does a postmortem add to the final diagnoses? |journal=BJOG |volume=112 |issue=7 |pages=935–40 |year=2005 |month=July |pmid=15957995 |doi=10.1111/j.1471-0528.2005.00608.x |url=}}</ref> | ||
*HIE in perinatal period may be unique to the specific time of the injury, i.e. the type of hypoxic insults vary by developmental stage.<ref name=pmid11876572>{{cite journal |author=Grafe MR, Kinney HC |title=Neuropathology associated with stillbirth |journal=Semin. Perinatol. |volume=26 |issue=1 |pages=83–8 |year=2002 |month=February |pmid=11876572 |doi= |url=}}</ref> | |||
**Some hypoxic injuries that are prenatal do not occur after birth. | |||
**Hypoxic-ischemic insults are predominantly in the white matter. | |||
==References== | ==References== | ||
Revision as of 13:26, 7 January 2011
The article deals with paediatric pathology, which is quite different than adult pathology. Many diseases that afflict children are uncommon or unheard of in adults.
Persistent pulmonary hypertension of the newborn
- Abbreviated PPHN.
- Related to patent ductus arteriosus and persistent fetal circulation.[1]
Associations:[2]
- Meconium aspiration.
- Anemia.
- Infection.
- Pneumonia (severe).
- Hypoglycemia.
- Birth asphyxia.
Hypoxic-ischemic encephalopathy
Main article: Neuropathology
- Abbreviated HIE.
- Autopsy adds some information.
- Two-tone liver - suggests prior injury.[3]
- HIE in perinatal period may be unique to the specific time of the injury, i.e. the type of hypoxic insults vary by developmental stage.[4]
- Some hypoxic injuries that are prenatal do not occur after birth.
- Hypoxic-ischemic insults are predominantly in the white matter.
References
- ↑ URL: http://www.thechildrenshospital.org/wellness/info/parents/20830.aspx. Accessed on: 4 January 2011.
- ↑ URL: http://www.thechildrenshospital.org/wellness/info/parents/20830.aspx. Accessed on: 4 January 2011.
- ↑ Elder DE, Zuccollo JM, Stanley TV (July 2005). "Neonatal death after hypoxic ischaemic encephalopathy: does a postmortem add to the final diagnoses?". BJOG 112 (7): 935–40. doi:10.1111/j.1471-0528.2005.00608.x. PMID 15957995.
- ↑ Grafe MR, Kinney HC (February 2002). "Neuropathology associated with stillbirth". Semin. Perinatol. 26 (1): 83–8. PMID 11876572.