Difference between revisions of "Hyperplastic polyp of the stomach"

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#redirect [[Stomach#Hyperplastic_polyp_of_the_stomach]]
{{ Infobox diagnosis
| Name      = {{PAGENAME}}
| Image      = Gastric_hyperplastic_polyp_%283%29_foveolar_type.jpg
| Width      =
| Caption    = Hyperplastic polyp of the stomach. [[H&E stain]].
| Micro      = abundant foveolar cells and elongated glands, +/-gland dilation
| Subtypes  =
| LMDDx      = [[fundic gland polyp]], [[juvenile polyp]], [[Peutz-Jeghers polyp]], [[Ménétrier's disease]]
| Stains    =
| IHC        =
| EM        =
| Molecular  =
| IF        =
| Gross      = polypoid mass
| Grossing  =
| Site      = [[stomach]]
| Assdx      =
| Syndromes  =
| Clinicalhx =
| Signs      =
| Symptoms  =
| Prevalence = common
| Bloodwork  =
| Rads      =
| Endoscopy  =
| Prognosis  = benign - good
| Other      =
| ClinDDx    = [[fundic gland polyp]], other gastric polyps
}}
'''Hyperplastic polyp of the stomach''', also '''gastric hyperplastic polyp''', is a common pathology of the [[stomach]]. Hyperplastic polyps more generally are dealt with in the ''[[hyperplastic polyp]]'' article.


==General==
*Benign.
*Most common gastric polyp.<ref name=pmid19037727/>
==Gross==
*Polypoid mass.
==Microscopic==
Features:<ref>URL: [http://pathologyoutlines.com/stomach.html#hyperplastic http://pathologyoutlines.com/stomach.html#hyperplastic]. Accessed on: 26 July 2011.</ref>
*Abundant foveolar cells and elongated glands - '''key feature'''.
*+/-Gland dilation.
Negatives:
*No atypical nuclei.
*No hyperchromasia.
*No loss of pseudostratification.
Notes:
*No serrations - as in the colon.
DDx:
*[[Ménétrier's disease]]<ref name=pmid18384215>{{Cite journal  | last1 = Park | first1 = do Y. | last2 = Lauwers | first2 = GY. | title = Gastric polyps: classification and management. | journal = Arch Pathol Lab Med | volume = 132 | issue = 4 | pages = 633-40 | month = Apr | year = 2008 | doi = 10.1043/1543-2165(2008)132[633:GPCAM]2.0.CO;2 | PMID = 18384215 | url=http://www.archivesofpathology.org/doi/full/10.1043/1543-2165(2008)132%5B633:GPCAM%5D2.0.CO;2 }}</ref> (hyperplastic hypersecretory gastropathy).
*[[Juvenile polyp]]<ref name=pmid19037727>{{Cite journal  | last1 = Jain | first1 = R. | last2 = Chetty | first2 = R. | title = Gastric hyperplastic polyps: a review. | journal = Dig Dis Sci | volume = 54 | issue = 9 | pages = 1839-46 | month = Sep | year = 2009 | doi = 10.1007/s10620-008-0572-8 | PMID = 19037727 }}</ref> - abundant lamina propria, dilated glands may have neutrophils.<ref name=Ref_GLP102>{{Ref GLP|102}}</ref>
*[[Peutz-Jeghers polyp]] - thick superficial muscle.
*[[Fundic gland polyp]] - doesn't have foveolar hyperplasia.
*Hyperplastic-like polyp in [[portal hypertensive gastropathy]].<ref name=pmid22002002>{{Cite journal  | last1 = Lam | first1 = MC. | last2 = Tha | first2 = S. | last3 = Owen | first3 = D. | last4 = Haque | first4 = M. | last5 = Chatur | first5 = N. | last6 = Gray | first6 = JR. | last7 = Yoshida | first7 = EM. | title = Gastric polyps in patients with portal hypertension. | journal = Eur J Gastroenterol Hepatol | volume = 23 | issue = 12 | pages = 1245-9 | month = Nov | year = 2011 | doi = 10.1097/MEG.0b013e32834c15cf | PMID = 22002002 }}</ref>
*Focal foveolar hyperplasia - foveolar epithelium not as tall (24 micrometres vs. 37 micrometres for a hyperplastic polyp).<ref>{{cite journal |author=Stolte M, Bethke B, Sticht T, Burkhard U |title=Differentiation of focal foveolar hyperplasia from hyperplastic polyps in gastric biopsy material |journal=Pathol. Res. Pract. |volume=191 |issue=12 |pages=1198–1202 |year=1995 |month=December |pmid=8927566 |doi=10.1016/S0344-0338(11)81126-X |url=}}</ref>
===Images===
<gallery>
Image: Gastric_hyperplastic_polyp_%281%29_foveolar_type.jpg | Gastric hyperplastic polyp - low mag. (WC/KGH)
Image: Gastric_hyperplastic_polyp_%283%29_foveolar_type.jpg | Gastric hyperplastic polyp - high mag. (WC/KGH)
</gallery>
www:
*[http://www.flickr.com/photos/jian-hua_qiao_md/3953137621/ Gastric hyperplastic polyp (flickr.com)].
*[http://www.flickr.com/photos/jian-hua_qiao_md/3953138195/in/photostream/ Gastric hyperplastic polyp (flickr.com)].
==Sign out==
<pre>
POLYP, STOMACH (ANTRUM), EXCISION:
- HYPERPLASTIC POLYP.
</pre>
===Micro===
The sections show antral-type gastric mucosa with hyperplastic gastric pits.  No gland dilation is apparent. The epithelium matures to the surface. The lamina propria is not expanded.
Focal neutrophilic inflammation is present. No Helicobacter-like organisms are identified. No intestinal metaplasia is present. No mitotic activity or nuclear atypia is apparent.
==See also==
*[[Hyperplastic polyp]] of the colon and rectum.
*[[Stomach]].
*[[Ménétrier's disease]].
==References==
{{Reflist|2}}
[[Category:Stomach]]
[[Category:Diagnosis]]
[[Category:Diagnosis]]

Latest revision as of 17:54, 9 June 2014

Hyperplastic polyp of the stomach
Diagnosis in short

Hyperplastic polyp of the stomach. H&E stain.
LM abundant foveolar cells and elongated glands, +/-gland dilation
LM DDx fundic gland polyp, juvenile polyp, Peutz-Jeghers polyp, Ménétrier's disease
Gross polypoid mass
Site stomach
Prevalence common
Prognosis benign - good
Clin. DDx fundic gland polyp, other gastric polyps

Hyperplastic polyp of the stomach, also gastric hyperplastic polyp, is a common pathology of the stomach. Hyperplastic polyps more generally are dealt with in the hyperplastic polyp article.

General

  • Benign.
  • Most common gastric polyp.[1]

Gross

  • Polypoid mass.

Microscopic

Features:[2]

  • Abundant foveolar cells and elongated glands - key feature.
  • +/-Gland dilation.

Negatives:

  • No atypical nuclei.
  • No hyperchromasia.
  • No loss of pseudostratification.

Notes:

  • No serrations - as in the colon.

DDx:

Images

  • Gastric hyperplastic polyp - low mag. (WC/KGH)

  • Gastric hyperplastic polyp - high mag. (WC/KGH)

www:

Sign out

POLYP, STOMACH (ANTRUM), EXCISION:
- HYPERPLASTIC POLYP.

Micro

The sections show antral-type gastric mucosa with hyperplastic gastric pits. No gland dilation is apparent. The epithelium matures to the surface. The lamina propria is not expanded.

Focal neutrophilic inflammation is present. No Helicobacter-like organisms are identified. No intestinal metaplasia is present. No mitotic activity or nuclear atypia is apparent.

See also

References

  1. ↑ 1.0 1.1 Jain, R.; Chetty, R. (Sep 2009). "Gastric hyperplastic polyps: a review.". Dig Dis Sci 54 (9): 1839-46. doi:10.1007/s10620-008-0572-8. PMID 19037727.
  2. ↑ URL: http://pathologyoutlines.com/stomach.html#hyperplastic. Accessed on: 26 July 2011.
  3. ↑ Park, do Y.; Lauwers, GY. (Apr 2008). "Gastric polyps: classification and management.". Arch Pathol Lab Med 132 (4): 633-40. doi:10.1043/1543-2165(2008)132[633:GPCAM]2.0.CO;2. PMID 18384215. http://www.archivesofpathology.org/doi/full/10.1043/1543-2165(2008)132%5B633:GPCAM%5D2.0.CO;2.
  4. ↑ Iacobuzio-Donahue, Christine A.; Montgomery, Elizabeth A. (2005). Gastrointestinal and Liver Pathology: A Volume in the Foundations in Diagnostic Pathology Series (1st ed.). Churchill Livingstone. pp. 102. ISBN 978-0443066573.
  5. ↑ Lam, MC.; Tha, S.; Owen, D.; Haque, M.; Chatur, N.; Gray, JR.; Yoshida, EM. (Nov 2011). "Gastric polyps in patients with portal hypertension.". Eur J Gastroenterol Hepatol 23 (12): 1245-9. doi:10.1097/MEG.0b013e32834c15cf. PMID 22002002.
  6. ↑ Stolte M, Bethke B, Sticht T, Burkhard U (December 1995). "Differentiation of focal foveolar hyperplasia from hyperplastic polyps in gastric biopsy material". Pathol. Res. Pract. 191 (12): 1198–1202. doi:10.1016/S0344-0338(11)81126-X. PMID 8927566.
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