Difference between revisions of "Case 58"
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Low magnification. H&E stain.
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===Provided clinical history=== | ===Provided clinical history=== | ||
24 year old man, testicular mass | |||
===Site=== | ===Site=== | ||
right testicle | |||
===Primary image=== | ===Primary image=== | ||
[[Image: | [[Image: Seminoma_with_syncytiotrophoblasts_-_low_mag.jpg |500px|link=|center|]] | ||
<center>Low magnification. [[H&E stain]].</center> | <center>Low magnification. [[H&E stain]].</center> | ||
{{hidden| | {{hidden|High magnification|[[Image: Seminoma_with_syncytiotrophoblasts_-_high_mag.jpg |500px|link=|center|]] | ||
<center>Intermediate magnification. [[H&E stain]].</center>}} | <center>Intermediate magnification. [[H&E stain]].</center>}} | ||
{{hidden| | {{hidden|Very high magnification|[[Image: Seminoma_with_syncytiotrophoblasts_-_very_high_mag.jpg |500px|link=|center|]] | ||
<center>High magnification. [[H&E stain]].</center>}} | <center>High magnification. [[H&E stain]].</center>}} | ||
<!-- | |||
===Differential diagnosis=== | ===Differential diagnosis=== | ||
{{hidden|Differential diagnosis|<center>THE DDx GOES HERE</center>}} | {{hidden|Differential diagnosis|<center>THE DDx GOES HERE</center>}} | ||
--> | |||
===Additional tests=== | ===Additional tests=== | ||
====More history==== | ====More history==== | ||
{{hidden|More history|<center> | {{hidden|More history|<center>Mass on ultrasound. Elevated serum beta-hCG.</center>}} | ||
====Ask a colleague==== | ====Ask a colleague==== | ||
{{hidden|Ask a colleague|<center> | {{hidden|Ask a colleague|<center>Multinucleated cells are present; these are probably syncytiotrophoblasts.</center>}} | ||
====Stains==== | ====Stains==== | ||
| Line 75: | Line 75: | ||
| acth= | | acth= | ||
| ae1ae3= | | ae1ae3= | ||
| afp= | | afp= '''NEGATIVE''' | ||
| alk1= | | alk1= | ||
| amacr= | | amacr= | ||
| Line 91: | Line 91: | ||
| cam5p2= | | cam5p2= | ||
| cd10= | | cd10= | ||
| cd117= | | cd117= '''POSITIVE''' | ||
| cd138= | | cd138= | ||
| cd15= | | cd15= | ||
| Line 128: | Line 128: | ||
| cmyc= | | cmyc= | ||
| cyclin_d1= | | cyclin_d1= | ||
| d2_40= | | d2_40= '''POSITIVE''' | ||
| desmin= | | desmin= | ||
| dog1= | | dog1= | ||
| Line 148: | Line 148: | ||
| hbv_surf= | | hbv_surf= | ||
| hcaldesmon= | | hcaldesmon= | ||
| hcg= | | hcg= '''POSITIVE''' in multinucleated cells | ||
| helicobacter= | | helicobacter= | ||
| hepatocyte= | | hepatocyte= | ||
| Line 181: | Line 181: | ||
| nf= | | nf= | ||
| nse= | | nse= | ||
| oct3_4= | | oct3_4= '''POSITIVE''' | ||
| p16= | | p16= | ||
| p53= | | p53= | ||
| Line 192: | Line 192: | ||
| pcna= | | pcna= | ||
| pdgfr= | | pdgfr= | ||
| plap= | | plap= '''POSITIVE''' | ||
| pnl-2c= | | pnl-2c= | ||
| prolactin= | | prolactin= | ||
| Line 242: | Line 242: | ||
===Diagnosis=== | ===Diagnosis=== | ||
{{hidden|Diagnosis|<center> | {{hidden|Diagnosis|<center>[[Seminoma]] with syncytiotrophoblasts</center>}} | ||
<br> | <br> | ||
===Other cases=== | ===Other cases=== | ||
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<!-- SELECT A CATEGORY | <!-- SELECT A CATEGORY | ||
[[Category:Cases in genitourinary pathology]] | [[Category:Cases in genitourinary pathology]] | ||
[[Category:Cases in genitourinary pathology - junior]] | |||
--> | --> | ||
[[Category:Cases difficulty | [[Category:Cases difficulty 2]] <!-- difficulty 1-7 -- should roughly correspond to the PGY level --> | ||
Revision as of 01:10, 26 May 2014
Provided clinical history
24 year old man, testicular mass
Site
right testicle
Primary image
High magnification
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Very high magnification
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Additional tests
More history
More history
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Ask a colleague
Ask a colleague
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Stains
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IHC
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Chromosomal translocations
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Diagnosis
Diagnosis
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