Difference between revisions of "Pulmonary hamartoma"

From Libre Pathology
Jump to navigation Jump to search
Line 19: Line 19:
Notes:
Notes:
*No nuclear atypia.
*No nuclear atypia.
DDx:
*Other [[lung tumours]] - especially slow growing ones.


===Images===
===Images===

Revision as of 16:39, 6 March 2014

Pulmonary hamartoma, also lung hamartoma, is a benign lesion of the lung that may be confused with malignancy.

General

  • Benign.

See also: Hamartoma.

Gross

  • Well circumscribed lesion.

Microscopic

Features:

  • Cartilage - key feature.
    • Single cells in lacunae surrounded by abundant matrix.
      • Paucicellular vis-a-vis malignant lesions.
  • Fat (adipocytes) - key feature.
  • Respiratory epithelium (columnar epithelium with cilia).

Notes:

  • No nuclear atypia.

DDx:

Images

www:

IHC

  • S100 +ve - highlights the fat.

Sign out

LUNG LESION, LEFT UPPER LOBE, WEDGE RESECTION:
- PULMONARY HAMARTOMA WITH MILD FOCAL ACUTE INFLAMMATION AND SURROUNDING EDEMA.
- SURROUNDING LUNG WITH MILD EMPHYSEMATOUS CHANGES.

Micro

The sections show lung with a well circumscribed lesion with a fibrous capsule partially lined by respiratory-type epithelium. The lesion consists of abundant respiratory epithelium and glands with focal sheeting and small collections of neutrophils focally. Small foci of degenerative changes are seen. The epithelium of the lesion as a gland cytomorphology. Mitotic activity is not readily apparent. Fat is not identified as a component of the lesion. Around the periphery of the lesion pulmonary edema is present.

The piece surrounding lung more distant from the lesion has mild emphysematous changes. No interstitial fibrosis is identified. No significant inflammation is present. The arteries are approximately the size of accompanying airway. The arteries have no appreciable intimal thickening.

See also

References