Difference between revisions of "Eosinophilic gastritis"
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COMMENT: | COMMENT: | ||
One of four tissue fragments has eosinophilia, with 45 eosinophils/1 HPF (where 1 HPF | |||
is 0.2376 mm*mm). | |||
</pre> | </pre> | ||
Revision as of 15:34, 3 February 2014
Eosinophilic gastritis, abbreviated EG, is an uncommon inflammatory process of stomach characterized by abundant eosinophils.
General
- Rare.
Gross
DDx:
Microscopic
Features:
- Abundant eosinophils -- >=127 eosinophils/mm2.[1]
- 30 eosinophils/HPF, if the field diameter of 1 HPF is 0.55 mm.
Notes:
- Normal range:[1]
- <38 eosinophils/mm2.
- Typically ~16 eosinophils/mm2.
- <38 eosinophils/mm2.
- Mild eosinophilia is seen in:[1]
- Crohn's disease ~ 31 eosinophils/mm2 (range: 0-203 eosinophils/mm2).
- Helicobacter gastritis ~ 25 eosinophils/mm2 (range: 0-219 eosinophils/mm2).
DDx:
- Chronic gastritis.
- Helicobacter gastritis.
- Crohn's disease - see inflammatory bowel disease and the stomach.
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STOMACH, BIOPSY: - BODY AND ANTRAL-TYPE GASTRIC MUCOSA WITH MODERATE CHRONIC ACTIVE INFLAMMATION WITH FOCAL EOSINOPHILIA. - NEGATIVE FOR HELICOBACTOR-LIKE ORGANISMS. - NEGATIVE FOR INTESTINAL METAPLASIA. - NEGATIVE FOR DYSPLASIA AND NEGATIVE FOR MALIGNANCY. COMMENT: One of four tissue fragments has eosinophilia, with 45 eosinophils/1 HPF (where 1 HPF is 0.2376 mm*mm).