Difference between revisions of "Parachordoma"
Jump to navigation
Jump to search
(create) |
|||
| Line 1: | Line 1: | ||
'''Parachordoma''' is a very rare paraspinal tumour that is similar to [[chordoma]].<ref name=pmid10809219>{{cite journal |author=Fisher C |title=Parachordoma exists--but what is it? |journal=Adv Anat Pathol |volume=7 |issue=3 |pages=141–8 |year=2000 |month=May |pmid=10809219 |doi= |url=}}</ref> | '''Parachordoma''' is a very rare paraspinal tumour that is similar to [[chordoma]].<ref name=pmid10809219>{{cite journal |author=Fisher C |title=Parachordoma exists--but what is it? |journal=Adv Anat Pathol |volume=7 |issue=3 |pages=141–8 |year=2000 |month=May |pmid=10809219 |doi= |url=}}</ref> | ||
==General== | |||
*Super rare - only approximately 30 cases reported.<ref name=pmid10478665/> | |||
==Microscopic== | |||
Features:<ref name=pmid10478665/> | |||
*Multivacuolated cells (physaliferous cell-like) - '''key feature'''. | |||
**May be rare. | |||
*"Large" rounded eosinophilic cells - '''important'''. | |||
*Variable matrix: | |||
**Myxoid. | |||
**Dense appearing hyaline - [[cartilage]]-like. | |||
*Small cells (spindled and rounded) - common. | |||
DDx: | |||
*[[Chordoma]]. | |||
*[[Extraskeletal myxoid chondrosarcoma]]. | |||
==Stains== | |||
*Alcian blue +ve (matrix).<ref name=pmid10478665/> | |||
==IHC== | ==IHC== | ||
<ref name=pmid10478665>{{Cite journal | last1 = Folpe| first1 = AL.| last2 = Agoff| first2 = SN.| last3 = Willis| first3 = J.| last4 = Weiss| first4 = SW.| title = Parachordoma is immunohistochemically and cytogenetically distinct from axial chordoma and extraskeletal myxoid chondrosarcoma.| journal = Am J Surg Pathol| volume = 23| issue = 9| pages = 1059-67| month = Sep| year = 1999| doi = | PMID = 10478665 }}</ref> | Features:<ref name=pmid10478665>{{Cite journal | last1 = Folpe| first1 = AL.| last2 = Agoff| first2 = SN.| last3 = Willis| first3 = J.| last4 = Weiss| first4 = SW.| title = Parachordoma is immunohistochemically and cytogenetically distinct from axial chordoma and extraskeletal myxoid chondrosarcoma.| journal = Am J Surg Pathol| volume = 23| issue = 9| pages = 1059-67| month = Sep| year = 1999| doi = | PMID = 10478665 }}</ref> | ||
*CK 8/18 +ve. | |||
*EMA +ve. | |||
*S-100 +ve. | |||
*Vimentin +ve. | |||
Note: | |||
*Other keratins negative. | |||
==See also== | |||
*[[Chordoma]]. | |||
==References== | ==References== | ||
Revision as of 03:24, 30 December 2013
Parachordoma is a very rare paraspinal tumour that is similar to chordoma.[1]
General
- Super rare - only approximately 30 cases reported.[2]
Microscopic
Features:[2]
- Multivacuolated cells (physaliferous cell-like) - key feature.
- May be rare.
- "Large" rounded eosinophilic cells - important.
- Variable matrix:
- Myxoid.
- Dense appearing hyaline - cartilage-like.
- Small cells (spindled and rounded) - common.
DDx:
Stains
- Alcian blue +ve (matrix).[2]
IHC
Features:[2]
- CK 8/18 +ve.
- EMA +ve.
- S-100 +ve.
- Vimentin +ve.
Note:
- Other keratins negative.
See also
References
- ↑ Fisher C (May 2000). "Parachordoma exists--but what is it?". Adv Anat Pathol 7 (3): 141–8. PMID 10809219.
- ↑ 2.0 2.1 2.2 2.3 Folpe, AL.; Agoff, SN.; Willis, J.; Weiss, SW. (Sep 1999). "Parachordoma is immunohistochemically and cytogenetically distinct from axial chordoma and extraskeletal myxoid chondrosarcoma.". Am J Surg Pathol 23 (9): 1059-67. PMID 10478665.