Difference between revisions of "Osteoarthritis"
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*Osteophytes are classically medial and lateral in the hip.<ref name=pmid12597129>{{Cite journal | last1 = Claassen | first1 = H. | last2 = Tschirner | first2 = T. | title = Topographical and histological examination of osteophytes taken from arthrotic femoral heads. | journal = Ann Anat | volume = 185 | issue = 1 | pages = 67-71 | month = Jan | year = 2003 | doi = | PMID = 12597129 }}</ref> | *Osteophytes are classically medial and lateral in the hip.<ref name=pmid12597129>{{Cite journal | last1 = Claassen | first1 = H. | last2 = Tschirner | first2 = T. | title = Topographical and histological examination of osteophytes taken from arthrotic femoral heads. | journal = Ann Anat | volume = 185 | issue = 1 | pages = 67-71 | month = Jan | year = 2003 | doi = | PMID = 12597129 }}</ref> | ||
**They tend to form in | **They tend to form in areas with high loading. | ||
==Microscopic== | ==Microscopic== | ||
Revision as of 13:02, 9 October 2012
Osteoarthritis, abbreviated OA, is a degenerative disease of the joint.
General
Risks
It is associated with:[1]
- Advanced age.
- Trauma.
- Unusual loading (bony misalignment, obesity).
Gross pathology/radiology
Features:[2]
- Loss of cartilage, especially asymmetrical.
- Marble-like appearance - polished appearance known as eburnation.
- Osteophyte formation.
- Subchondral cysts.
- Subchondral sclerosis.
Memory device LOSS:
- Loss of cartilage, Osteophyte formation, Subchondral cysts, Subchondral sclerosis.
Notes:
- Osteophytes are classically medial and lateral in the hip.[3]
- They tend to form in areas with high loading.
Microscopic
Features:[4]
- Vertical clefts of the cartilage - characteristic.
- Thickening of bony trabeculae (reactive phenomenon) due to fibrosis.
- Subchondral cysts.
- +/-Mild inflammation (lymphocytes).
- +/-Villous hyperplasia - synovium has finger-like projections into the joint space.
- Normal synovium has a flat surface.
Image:
See also
References
- ↑ Martel-Pelletier, J.; Pelletier, JP. (Apr 2010). "Is osteoarthritis a disease involving only cartilage or other articular tissues?". Eklem Hastalik Cerrahisi 21 (1): 2-14. PMID 20302555. http://www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--www.tevak.org-images-Eklemlinkout.png.
- ↑ Swagerty, DL.; Hellinger, D. (Jul 2001). "Radiographic assessment of osteoarthritis.". Am Fam Physician 64 (2): 279-86. PMID 11476273. http://www.aafp.org/afp/2001/0715/p279.html.
- ↑ Claassen, H.; Tschirner, T. (Jan 2003). "Topographical and histological examination of osteophytes taken from arthrotic femoral heads.". Ann Anat 185 (1): 67-71. PMID 12597129.
- ↑ Humphrey, Peter A; Dehner, Louis P; Pfeifer, John D (2008). The Washington Manual of Surgical Pathology (1st ed.). Lippincott Williams & Wilkins. pp. 658. ISBN 978-0781765275.
