Difference between revisions of "Apoptosis"
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*Apoptotic bodies (membrane bound cell fragments) - '''key feature'''. | *Apoptotic bodies (membrane bound cell fragments) - '''key feature'''. | ||
*Cell shrinkage. | *Cell shrinkage. | ||
*Cytoplasm usu. eosinophilic (pink). | |||
*Lack of inflammation, i.e. [[neutrophils]]. | *Lack of inflammation, i.e. [[neutrophils]]. | ||
Revision as of 16:00, 5 May 2012
Apoptosis is programmed/controlled cell death. It can be physiologic, i.e. normal, or pathologic.
Physiologic apoptosis
Examples:[1]
- Removal of self reactive lymhocytes.
- Death of cells at the end of their life:
- Neurophils.
- Enterocytes.
- Embryogenesis.
- Endometrium - during mentruation.[2]
Microscopic
Features:[3]
- Apoptotic bodies (membrane bound cell fragments) - key feature.
- Cell shrinkage.
- Cytoplasm usu. eosinophilic (pink).
- Lack of inflammation, i.e. neutrophils.
See also
References
- ↑ Mitchell, Richard; Kumar, Vinay; Fausto, Nelson; Abbas, Abul K.; Aster, Jon (2011). Pocket Companion to Robbins & Cotran Pathologic Basis of Disease (8th ed.). Elsevier Saunders. pp. 13. ISBN 978-1416054542.
- ↑ Kokawa, K.; Shikone, T.; Nakano, R. (Nov 1996). "Apoptosis in the human uterine endometrium during the menstrual cycle.". J Clin Endocrinol Metab 81 (11): 4144-7. PMID 8923873.
- ↑ Mitchell, Richard; Kumar, Vinay; Fausto, Nelson; Abbas, Abul K.; Aster, Jon (2011). Pocket Companion to Robbins & Cotran Pathologic Basis of Disease (8th ed.). Elsevier Saunders. pp. 4. ISBN 978-1416054542.