Difference between revisions of "Electron microscopy"

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Seen in:
Seen in:
*[[Neuroendocrine carcinoma]].
*[[Neuroendocrine carcinoma]].
**[[Merkel cell carcinoma]].
**[[Merkel cell carcinoma]].<ref name=pmid9062165>{{Cite journal  | last1 = Gil-Moreno | first1 = A. | last2 = Garcia-Jiménez | first2 = A. | last3 = González-Bosquet | first3 = J. | last4 = Esteller | first4 = M. | last5 = Castellví-Vives | first5 = J. | last6 = Martínez Palones | first6 = JM. | last7 = Xercavins | first7 = J. | title = Merkel cell carcinoma of the vulva. | journal = Gynecol Oncol | volume = 64 | issue = 3 | pages = 526-32 | month = Mar | year = 1997 | doi =  | PMID = 9062165 }}</ref>


===Ultrastructure===
===Ultrastructure===

Revision as of 02:04, 5 May 2012

This article collection stuffs about electron microscopy. It is commonly abbreviated EM.

Glycogen

Appearance:

  • Cytoplasmic, electron dense, not bound by a membrane.

Seen in:

Tubuloreticular inclusions

Abbreviated TRIs.

Appearance:

  • Undulating tubules in the smooth ER, usu. perinuclear.[1]

Seen in:

Melanosomes

Appearance:

  • Membrane bound, sausage-like shape.

Image(s):

Seen in:

Neurosecretory granules

  • AKA dense-core granules.

General

Seen in:

Ultrastructure

Appearance:[3]

  • Round membrane bound, granular core.
  • Size: 100-400 nm.

Image(s):

Birbeck granules

Appearance:

  • Electron dense, cytoplasmic tennis racket-like body.

Image(s):

Malignant mesothelioma

Several EM features can be useful to distinguish mesothelioma from adenocarcinoma as per Warhol et al:[4]

  • Microvillous length -- longer in mesothelioma.
  • Quantity of intermediate filaments -- mesothelioma have more.

See also

References

  1. Stoltenburg-Didinger G, Genth E (June 2009). "[Dermatomyositis]" (in German). Z Rheumatol 68 (4): 287–94. doi:10.1007/s00393-008-0398-y. PMID 19330338.
  2. Gil-Moreno, A.; Garcia-Jiménez, A.; González-Bosquet, J.; Esteller, M.; Castellví-Vives, J.; Martínez Palones, JM.; Xercavins, J. (Mar 1997). "Merkel cell carcinoma of the vulva.". Gynecol Oncol 64 (3): 526-32. PMID 9062165.
  3. URL: http://www.pathologyimagesinc.com/emhandbook/diagn-organelles-section/organelle-pages/neuroendo-granules.html. Accessed on: 11 February 2011.
  4. Warhol, MJ.; Hickey, WF.; Corson, JM. (Jun 1982). "Malignant mesothelioma: ultrastructural distinction from adenocarcinoma.". Am J Surg Pathol 6 (4): 307-14. PMID 6287872.

External links