Difference between revisions of "Electron microscopy"
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*[[Melanoma]]. | *[[Melanoma]]. | ||
== | ==Neurosecretory granules== | ||
*[[AKA]] '' | *[[AKA]] ''dense-core granules''. | ||
===General=== | |||
Seen in: | |||
*[[Neuroendocrine carcinoma]]. | |||
**[[Merkel cell carcinoma]]. | |||
===Ultrastructure=== | |||
Appearance:<ref>URL: [http://www.pathologyimagesinc.com/emhandbook/diagn-organelles-section/organelle-pages/neuroendo-granules.html http://www.pathologyimagesinc.com/emhandbook/diagn-organelles-section/organelle-pages/neuroendo-granules.html]. Accessed on: 11 February 2011.</ref> | Appearance:<ref>URL: [http://www.pathologyimagesinc.com/emhandbook/diagn-organelles-section/organelle-pages/neuroendo-granules.html http://www.pathologyimagesinc.com/emhandbook/diagn-organelles-section/organelle-pages/neuroendo-granules.html]. Accessed on: 11 February 2011.</ref> | ||
*Round membrane bound, granular core. | *Round membrane bound, granular core. | ||
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Image(s): | Image(s): | ||
*[http://pathhsw5m54.ucsf.edu/case7/image77.html Neuroendocrine tumours (ucsf.edu)]. | *[http://pathhsw5m54.ucsf.edu/case7/image77.html Neuroendocrine tumours (ucsf.edu)]. | ||
==Birbeck granules== | ==Birbeck granules== | ||
Revision as of 02:03, 5 May 2012
This article collection stuffs about electron microscopy. It is commonly abbreviated EM.
Glycogen
Appearance:
- Cytoplasmic, electron dense, not bound by a membrane.
Seen in:
Tubuloreticular inclusions
Abbreviated TRIs.
Appearance:
- Undulating tubules in the smooth ER, usu. perinuclear.[1]
Seen in:
Melanosomes
Appearance:
- Membrane bound, sausage-like shape.
Image(s):
Seen in:
Neurosecretory granules
- AKA dense-core granules.
General
Seen in:
Ultrastructure
Appearance:[2]
- Round membrane bound, granular core.
- Size: 100-400 nm.
Image(s):
Birbeck granules
- Seen in Langerhans cell histiocytosis.
Appearance:
- Electron dense, cytoplasmic tennis racket-like body.
Image(s):
- Birbeck granules (photobucket.com).
- Usually... only the handle of the tennis racket is well seen.
Malignant mesothelioma
Main article: Malignant mesothelioma
Several EM features can be useful to distinguish mesothelioma from adenocarcinoma as per Warhol et al:[3]
- Microvillous length -- longer in mesothelioma.
- Quantity of intermediate filaments -- mesothelioma have more.
See also
References
- ↑ Stoltenburg-Didinger G, Genth E (June 2009). "[Dermatomyositis]" (in German). Z Rheumatol 68 (4): 287–94. doi:10.1007/s00393-008-0398-y. PMID 19330338.
- ↑ URL: http://www.pathologyimagesinc.com/emhandbook/diagn-organelles-section/organelle-pages/neuroendo-granules.html. Accessed on: 11 February 2011.
- ↑ Warhol, MJ.; Hickey, WF.; Corson, JM. (Jun 1982). "Malignant mesothelioma: ultrastructural distinction from adenocarcinoma.". Am J Surg Pathol 6 (4): 307-14. PMID 6287872.