Cowper gland adenocarcinoma

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Cowper gland adenocarcinoma, also bulbourethral gland adenocarcinoma, is a cancer of the bulbourethral gland. It is very rare.

General

  • Extremely rare - 9 reported cases in 2016.[1]

Microscopic

Features:[2][3]

  • Cribriform or trabecular or solid pattern.
  • Cytologically bland morphology.

DDx:

IHC

Features:[2]

  • CK7 +ve.
  • HWCK +ve.
  • PSA -ve.
  • PSAP -ve.
  • SMA -ve.
  • S-100 -ve.

See also

References

  1. Zhang M, Pettaway C, Vikram R, Tamboli P (December 2016). "Adenoid cystic carcinoma of the urethra/Cowper's gland with concurrent high-grade prostatic adenocarcinoma: a detailed clinicopathologic case report and review of the literature". Hum Pathol 58: 138–144. doi:10.1016/j.humpath.2016.07.027. PMID 27554206.
  2. 2.0 2.1 WHO Classification of Tumours Editorial Board (2022). Urinary and Male Genital Tumours (5th ed.). Lyon: World Health Organization. pp. 187. ISBN 978-9283245124.
  3. Small JD, Albertsen PC, Graydon RJ, Ricci A, Sardella WV (March 1992). "Adenoid cystic carcinoma of Cowper's gland". J Urol 147 (3): 699–701. doi:10.1016/s0022-5347(17)37357-3. PMID 1311394.