Xanthogranulomatous cholecystitis - Revision history

Michael: tweak

2016-05-31T03:54:17Z

tweak

← Older revision		Revision as of 03:54, 31 May 2016
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	\| Molecular =		\| Molecular =
	\| IF =		\| IF =
	\| Gross =		\| Gross = thickened gallbladder wall, [[gallstones]]
	\| Grossing =		\| Grossing =
	\| Site = [[gallbladder]]		\| Site = [[gallbladder]]
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	\| Signs =		\| Signs =
	\| Symptoms =		\| Symptoms =
	\| Prevalence =		\| Prevalence = uncommon
	\| Bloodwork =		\| Bloodwork =
	\| Rads =		\| Rads = hypo-attenuated nodules in gallbladder wall
	\| Endoscopy =		\| Endoscopy =
	\| Prognosis =		\| Prognosis = benign
	\| Other =		\| Other =
	\| ClinDDx = [[gallbladder carcinoma]], [[acute cholecystitis]]		\| ClinDDx = [[gallbladder carcinoma]], [[acute cholecystitis]]
			\| Tx = cholecystectomy (surgical removal)
	}}		}}
	'''Xanthogranulomatous cholecystitis''', abbreviated '''XGC''',<ref name=pmid25404941>{{Cite journal \| last1 = Rammohan \| first1 = A. \| last2 = Cherukuri \| first2 = SD. \| last3 = Sathyanesan \| first3 = J. \| last4 = Palaniappan \| first4 = R. \| last5 = Govindan \| first5 = M. \| title = Xanthogranulomatous cholecystitis masquerading as gallbladder cancer: can it be diagnosed preoperatively? \| journal = Gastroenterol Res Pract \| volume = 2014 \| issue = \| pages = 253645 \| month = \| year = 2014 \| doi = 10.1155/2014/253645 \| PMID = 25404941 }}</ref> is an uncommon pathology of the [[gallbladder]].		'''Xanthogranulomatous cholecystitis''', abbreviated '''XGC''',<ref name=pmid25404941>{{Cite journal \| last1 = Rammohan \| first1 = A. \| last2 = Cherukuri \| first2 = SD. \| last3 = Sathyanesan \| first3 = J. \| last4 = Palaniappan \| first4 = R. \| last5 = Govindan \| first5 = M. \| title = Xanthogranulomatous cholecystitis masquerading as gallbladder cancer: can it be diagnosed preoperatively? \| journal = Gastroenterol Res Pract \| volume = 2014 \| issue = \| pages = 253645 \| month = \| year = 2014 \| doi = 10.1155/2014/253645 \| PMID = 25404941 }}</ref> is an uncommon pathology of the [[gallbladder]].

Michael: /* Sign out */

2016-01-06T14:30:29Z

Sign out

← Older revision		Revision as of 14:30, 6 January 2016
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	==Sign out==		==Sign out==
			<pre>
			Gallbladder, Cholecystectomy:
			- Xanthogranulomatous cholecystitis.
			- Cholelithiasis.
			</pre>

			===Block letters===
	<pre>		<pre>
	GALLBLADDER, CHOLECYSTECTOMY:		GALLBLADDER, CHOLECYSTECTOMY:

Michael at 14:28, 6 January 2016

2016-01-06T14:28:06Z

← Older revision		Revision as of 14:28, 6 January 2016
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	\| ClinDDx = [[gallbladder carcinoma]], [[acute cholecystitis]]		\| ClinDDx = [[gallbladder carcinoma]], [[acute cholecystitis]]
	}}		}}
	'''Xanthogranulomatous cholecystitis''', abbreviated '''XGC''', is an uncommon pathology of the [[gallbladder]].		'''Xanthogranulomatous cholecystitis''', abbreviated '''XGC''',<ref name=pmid25404941>{{Cite journal \| last1 = Rammohan \| first1 = A. \| last2 = Cherukuri \| first2 = SD. \| last3 = Sathyanesan \| first3 = J. \| last4 = Palaniappan \| first4 = R. \| last5 = Govindan \| first5 = M. \| title = Xanthogranulomatous cholecystitis masquerading as gallbladder cancer: can it be diagnosed preoperatively? \| journal = Gastroenterol Res Pract \| volume = 2014 \| issue = \| pages = 253645 \| month = \| year = 2014 \| doi = 10.1155/2014/253645 \| PMID = 25404941 }}</ref> is an uncommon pathology of the [[gallbladder]].

	==General==		==General==
	*Uncommon ~ 1-9%.<ref name=pmid23991684>{{Cite journal \| last1 = Hale \| first1 = MD. \| last2 = Roberts \| first2 = KJ. \| last3 = Hodson \| first3 = J. \| last4 = Scott \| first4 = N. \| last5 = Sheridan \| first5 = M. \| last6 = Toogood \| first6 = GJ. \| title = Xanthogranulomatous cholecystitis: a European and global perspective. \| journal = HPB (Oxford) \| volume = \| issue = \| pages = \| month = Aug \| year = 2013 \| doi = 10.1111/hpb.12152 \| PMID = 23991684 }}</ref><ref name=pmid24019688>{{Cite journal \| last1 = Alvi \| first1 = AR. \| last2 = Jalbani \| first2 = I. \| last3 = Murtaza \| first3 = G. \| last4 = Hameed \| first4 = A. \| title = Outcomes of Xanthogranulomatous cholecystitis in laparoscopic era: A retrospective Cohort study. \| journal = J Minim Access Surg \| volume = 9 \| issue = 3 \| pages = 109-15 \| month = Jul \| year = 2013 \| doi = 10.4103/0972-9941.115368 \| PMID = 24019688 }}</ref>		*Uncommon ~ 1-9%.<ref name=pmid23991684>{{Cite journal \| last1 = Hale \| first1 = MD. \| last2 = Roberts \| first2 = KJ. \| last3 = Hodson \| first3 = J. \| last4 = Scott \| first4 = N. \| last5 = Sheridan \| first5 = M. \| last6 = Toogood \| first6 = GJ. \| title = Xanthogranulomatous cholecystitis: a European and global perspective. \| journal = HPB (Oxford) \| volume = \| issue = \| pages = \| month = Aug \| year = 2013 \| doi = 10.1111/hpb.12152 \| PMID = 23991684 }}</ref><ref name=pmid24019688>{{Cite journal \| last1 = Alvi \| first1 = AR. \| last2 = Jalbani \| first2 = I. \| last3 = Murtaza \| first3 = G. \| last4 = Hameed \| first4 = A. \| title = Outcomes of Xanthogranulomatous cholecystitis in laparoscopic era: A retrospective Cohort study. \| journal = J Minim Access Surg \| volume = 9 \| issue = 3 \| pages = 109-15 \| month = Jul \| year = 2013 \| doi = 10.4103/0972-9941.115368 \| PMID = 24019688 }}</ref>
	**Approximately 2% in one series of 724 gallbladders.<ref name=pmid3584484>{{Cite journal \| last1 = Roberts \| first1 = KM. \| last2 = Parsons \| first2 = MA. \| title = Xanthogranulomatous cholecystitis: clinicopathological study of 13 cases. \| journal = J Clin Pathol \| volume = 40 \| issue = 4 \| pages = 412-7 \| month = Apr \| year = 1987 \| doi = \| PMID = 3584484 \| PMC = 1140974 }}</ref>		**Approximately 2% in one series of 724 gallbladders.<ref name=pmid3584484>{{Cite journal \| last1 = Roberts \| first1 = KM. \| last2 = Parsons \| first2 = MA. \| title = Xanthogranulomatous cholecystitis: clinicopathological study of 13 cases. \| journal = J Clin Pathol \| volume = 40 \| issue = 4 \| pages = 412-7 \| month = Apr \| year = 1987 \| doi = \| PMID = 3584484 \| PMC = 1140974 }}</ref>
	*May be confused (clinically) with [[gallbladder carcinoma]].<ref name=pmid23991684/><ref name=pmid23060404>{{Cite journal \| last1 = Martins \| first1 = PN. \| last2 = Sheiner \| first2 = P. \| last3 = Facciuto \| first3 = M. \| title = Xanthogranulomatous cholecystitis mimicking gallbladder cancer and causing obstructive cholestasis. \| journal = Hepatobiliary Pancreat Dis Int \| volume = 11 \| issue = 5 \| pages = 549-52 \| month = Oct \| year = 2012 \| doi = \| PMID = 23060404 }}</ref>		*May be confused (clinically) with [[gallbladder carcinoma]].<ref name=pmid25404941/><ref name=pmid23991684/><ref name=pmid23060404>{{Cite journal \| last1 = Martins \| first1 = PN. \| last2 = Sheiner \| first2 = P. \| last3 = Facciuto \| first3 = M. \| title = Xanthogranulomatous cholecystitis mimicking gallbladder cancer and causing obstructive cholestasis. \| journal = Hepatobiliary Pancreat Dis Int \| volume = 11 \| issue = 5 \| pages = 549-52 \| month = Oct \| year = 2012 \| doi = \| PMID = 23060404 }}</ref>

	==Gross==		==Gross==
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	www:		www:
	*[http://www.radiologycases.com/index.php/radiologycases/article/view/696 XGC (radiologycases.com)].<ref>{{Cite journal \| last1 = Cecava \| first1 = ND. \| last2 = Andrews \| first2 = R. \| title = Case report of xanthogranulomatous cholecystitis, review of its sonographic and magnetic resonance findings, and distinction from other gallbladder pathology. \| journal = J Radiol Case Rep \| volume = 5 \| issue = 4 \| pages = 19-24 \| month = \| year = 2011 \| doi = 10.3941/jrcr.v5i4.696 \| PMID = 22470787 }}</ref>		*[http://www.radiologycases.com/index.php/radiologycases/article/view/696 XGC (radiologycases.com)].<ref>{{Cite journal \| last1 = Cecava \| first1 = ND. \| last2 = Andrews \| first2 = R. \| title = Case report of xanthogranulomatous cholecystitis, review of its sonographic and magnetic resonance findings, and distinction from other gallbladder pathology. \| journal = J Radiol Case Rep \| volume = 5 \| issue = 4 \| pages = 19-24 \| month = \| year = 2011 \| doi = 10.3941/jrcr.v5i4.696 \| PMID = 22470787 }}</ref>
			*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227324/figure/fig3/ XGC (nih.gov)].<ref name=pmid25404941/>

	==Sign out==		==Sign out==

Michael: /* Micro */

2014-05-26T10:58:03Z

Micro

← Older revision		Revision as of 10:58, 26 May 2014
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	giant cells, fibrosis and lymphoid aggregates. No metaplasia, nuclear atypia or dysplasia		giant cells, fibrosis and lymphoid aggregates. No metaplasia, nuclear atypia or dysplasia
	is apparent.		is apparent.

			====Alternate====
			The sections show a thickened gallbladder wall with cholesterol clefts, multinucleated
			giant cells, fibrosis and small lymphoid aggregates. No metaplasia, dysplasia or
			significant nuclear atypia is apparent.

	==See also==		==See also==

Michael: /* Microscopic */

2013-12-26T14:07:59Z

Microscopic

← Older revision		Revision as of 14:07, 26 December 2013
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	*[[Gallbladder cholesterolosis]].		*[[Gallbladder cholesterolosis]].

	Image:		===Images===
			<gallery>
			Image: Xanthogranulomatous cholecystitis -- low mag.jpg \| XGC - low mag. (WC)
			Image: Xanthogranulomatous cholecystitis -- intermed mag.jpg \| XGC - intermed. mag. (WC)
			Image: Xanthogranulomatous cholecystitis - alt -- intermed mag.jpg \| XGC - intermed. mag. (WC)
			Image: Xanthogranulomatous cholecystitis -- high mag.jpg \| XGC - high mag. (WC)
			Image: Xanthogranulomatous cholecystitis -- very high mag.jpg \| XGC - very high mag. (WC)
			</gallery>
			www:
	*[http://www.radiologycases.com/index.php/radiologycases/article/view/696 XGC (radiologycases.com)].<ref>{{Cite journal \| last1 = Cecava \| first1 = ND. \| last2 = Andrews \| first2 = R. \| title = Case report of xanthogranulomatous cholecystitis, review of its sonographic and magnetic resonance findings, and distinction from other gallbladder pathology. \| journal = J Radiol Case Rep \| volume = 5 \| issue = 4 \| pages = 19-24 \| month = \| year = 2011 \| doi = 10.3941/jrcr.v5i4.696 \| PMID = 22470787 }}</ref>		*[http://www.radiologycases.com/index.php/radiologycases/article/view/696 XGC (radiologycases.com)].<ref>{{Cite journal \| last1 = Cecava \| first1 = ND. \| last2 = Andrews \| first2 = R. \| title = Case report of xanthogranulomatous cholecystitis, review of its sonographic and magnetic resonance findings, and distinction from other gallbladder pathology. \| journal = J Radiol Case Rep \| volume = 5 \| issue = 4 \| pages = 19-24 \| month = \| year = 2011 \| doi = 10.3941/jrcr.v5i4.696 \| PMID = 22470787 }}</ref>

Michael at 14:03, 26 December 2013

2013-12-26T14:03:02Z

← Older revision		Revision as of 14:03, 26 December 2013
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	{{ Infobox diagnosis		{{ Infobox diagnosis
	\| Name = {{PAGENAME}}		\| Name = {{PAGENAME}}
	\| Image =		\| Image = Xanthogranulomatous cholecystitis -- low mag.jpg
	\| Width =		\| Width =
	\| Caption =		\| Caption = Xanthogranulomatous cholecystitis. [[H&E stain]].
	\| Micro = cholesterol clefts, [[granulomas]]		\| Micro = cholesterol clefts, [[granulomas]]
	\| Subtypes =		\| Subtypes =

Michael at 20:13, 26 November 2013

2013-11-26T20:13:24Z

← Older revision		Revision as of 20:13, 26 November 2013
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	==General==		==General==
	*Uncommon ~ 1-9%.<ref name=pmid23991684>{{Cite journal \| last1 = Hale \| first1 = MD. \| last2 = Roberts \| first2 = KJ. \| last3 = Hodson \| first3 = J. \| last4 = Scott \| first4 = N. \| last5 = Sheridan \| first5 = M. \| last6 = Toogood \| first6 = GJ. \| title = Xanthogranulomatous cholecystitis: a European and global perspective. \| journal = HPB (Oxford) \| volume = \| issue = \| pages = \| month = Aug \| year = 2013 \| doi = 10.1111/hpb.12152 \| PMID = 23991684 }}</ref><ref name=pmid24019688>{{Cite journal \| last1 = Alvi \| first1 = AR. \| last2 = Jalbani \| first2 = I. \| last3 = Murtaza \| first3 = G. \| last4 = Hameed \| first4 = A. \| title = Outcomes of Xanthogranulomatous cholecystitis in laparoscopic era: A retrospective Cohort study. \| journal = J Minim Access Surg \| volume = 9 \| issue = 3 \| pages = 109-15 \| month = Jul \| year = 2013 \| doi = 10.4103/0972-9941.115368 \| PMID = 24019688 }}</ref>		*Uncommon ~ 1-9%.<ref name=pmid23991684>{{Cite journal \| last1 = Hale \| first1 = MD. \| last2 = Roberts \| first2 = KJ. \| last3 = Hodson \| first3 = J. \| last4 = Scott \| first4 = N. \| last5 = Sheridan \| first5 = M. \| last6 = Toogood \| first6 = GJ. \| title = Xanthogranulomatous cholecystitis: a European and global perspective. \| journal = HPB (Oxford) \| volume = \| issue = \| pages = \| month = Aug \| year = 2013 \| doi = 10.1111/hpb.12152 \| PMID = 23991684 }}</ref><ref name=pmid24019688>{{Cite journal \| last1 = Alvi \| first1 = AR. \| last2 = Jalbani \| first2 = I. \| last3 = Murtaza \| first3 = G. \| last4 = Hameed \| first4 = A. \| title = Outcomes of Xanthogranulomatous cholecystitis in laparoscopic era: A retrospective Cohort study. \| journal = J Minim Access Surg \| volume = 9 \| issue = 3 \| pages = 109-15 \| month = Jul \| year = 2013 \| doi = 10.4103/0972-9941.115368 \| PMID = 24019688 }}</ref>
	**Approximately 2% in one series of gallbladders.<ref name=pmid3584484>{{Cite journal \| last1 = Roberts \| first1 = KM. \| last2 = Parsons \| first2 = MA. \| title = Xanthogranulomatous cholecystitis: clinicopathological study of 13 cases. \| journal = J Clin Pathol \| volume = 40 \| issue = 4 \| pages = 412-7 \| month = Apr \| year = 1987 \| doi = \| PMID = 3584484 \| PMC = 1140974 }}</ref>		**Approximately 2% in one series of 724 gallbladders.<ref name=pmid3584484>{{Cite journal \| last1 = Roberts \| first1 = KM. \| last2 = Parsons \| first2 = MA. \| title = Xanthogranulomatous cholecystitis: clinicopathological study of 13 cases. \| journal = J Clin Pathol \| volume = 40 \| issue = 4 \| pages = 412-7 \| month = Apr \| year = 1987 \| doi = \| PMID = 3584484 \| PMC = 1140974 }}</ref>
	*May be confused (clinically) with [[gallbladder carcinoma]].<ref name=pmid23991684/><ref name=pmid23060404>{{Cite journal \| last1 = Martins \| first1 = PN. \| last2 = Sheiner \| first2 = P. \| last3 = Facciuto \| first3 = M. \| title = Xanthogranulomatous cholecystitis mimicking gallbladder cancer and causing obstructive cholestasis. \| journal = Hepatobiliary Pancreat Dis Int \| volume = 11 \| issue = 5 \| pages = 549-52 \| month = Oct \| year = 2012 \| doi = \| PMID = 23060404 }}</ref>		*May be confused (clinically) with [[gallbladder carcinoma]].<ref name=pmid23991684/><ref name=pmid23060404>{{Cite journal \| last1 = Martins \| first1 = PN. \| last2 = Sheiner \| first2 = P. \| last3 = Facciuto \| first3 = M. \| title = Xanthogranulomatous cholecystitis mimicking gallbladder cancer and causing obstructive cholestasis. \| journal = Hepatobiliary Pancreat Dis Int \| volume = 11 \| issue = 5 \| pages = 549-52 \| month = Oct \| year = 2012 \| doi = \| PMID = 23060404 }}</ref>

Michael: /* Micro */

2013-11-26T20:12:17Z

Micro

← Older revision		Revision as of 20:12, 26 November 2013
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	===Micro===		===Micro===
	The sections show gallbladder wall with cholesterol clefts, multinucleated giant cells and		The sections show a thickened gallbladder wall with cholesterol clefts, multinucleated
	~~mononuclear cells~~. No metaplasia, nuclear atypia or dysplasia is apparent.		giant cells, fibrosis and lymphoid aggregates. No metaplasia, nuclear atypia or dysplasia
			is apparent.

	==See also==		==See also==

Michael at 20:08, 26 November 2013

2013-11-26T20:08:36Z

← Older revision		Revision as of 20:08, 26 November 2013
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	\| Micro = cholesterol clefts, [[granulomas]]		\| Micro = cholesterol clefts, [[granulomas]]
	\| Subtypes =		\| Subtypes =
	\| LMDDx =		\| LMDDx = [[chronic cholecystitis]], [[gallbladder cholesterolosis]]
	\| Stains =		\| Stains =
	\| IHC =		\| IHC =

Michael at 20:08, 26 November 2013

2013-11-26T20:08:01Z

← Older revision		Revision as of 20:08, 26 November 2013
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	==Microscopic==		==Microscopic==
	Features:<ref name=pmid3584484>{{Cite journal \| last1 = Roberts \| first1 = KM. \| last2 = Parsons \| first2 = MA. \| title = Xanthogranulomatous cholecystitis: clinicopathological study of 13 cases. \| journal = J Clin Pathol \| volume = 40 \| issue = 4 \| pages = 412-7 \| month = Apr \| year = 1987 \| doi = \| PMID = 3584484 \| PMC = 1140974 }}</ref>		Features:<ref name=pmid3584484>{{Cite journal \| last1 = Roberts \| first1 = KM. \| last2 = Parsons \| first2 = MA. \| title = Xanthogranulomatous cholecystitis: clinicopathological study of 13 cases. \| journal = J Clin Pathol \| volume = 40 \| issue = 4 \| pages = 412-7 \| month = Apr \| year = 1987 \| doi = \| PMID = 3584484 \| PMC = 1140974 }}</ref>
			*[[Granulomas]].
			*Lipid-laden macrophages.
			*+/-Cholesterol clefts.
	*Inflammatory cells.		*Inflammatory cells.
	*Fibrosis.		*Fibrosis.
	*Lipid-laden macrophages.
	*~~+/-Cholesterol clefts~~.		DDx:
	*[[~~Granulomas~~]].		*[[Chronic cholecystitis]].
			*[[Gallbladder cholesterolosis]].

	Image:		Image: