Urinary bladder metastasis - Revision history

Michael at 03:59, 17 January 2017

2017-01-17T03:59:44Z

← Older revision		Revision as of 03:59, 17 January 2017
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	\| Assdx =		\| Assdx =
	\| Syndromes =		\| Syndromes =
	\| Clinicalhx = +/-history cancer		\| Clinicalhx = +/-history of cancer
	\| Signs =		\| Signs =
	\| Symptoms = hematuria (typical)		\| Symptoms = hematuria (typical)

Michael at 03:59, 17 January 2017

2017-01-17T03:59:17Z

← Older revision		Revision as of 03:59, 17 January 2017
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	\| LMDDx = [[urothelial carcinoma]] with unusual features, [[primary adenocarcinoma of the urinary bladder]], direct extension of non-bladder primary tumour in bladder (e.g. [[prostate cancer\|prostate]], rectum, [[urachal carcinoma]])		\| LMDDx = [[urothelial carcinoma]] with unusual features, [[primary adenocarcinoma of the urinary bladder]], direct extension of non-bladder primary tumour in bladder (e.g. [[prostate cancer\|prostate]], rectum, [[urachal carcinoma]])
	\| Stains =		\| Stains =
	\| IHC = [[GATA3]] -ve (commonly +ve in breast), beta-catenin +ve/-ve (nuclear staining - suggests colorectal primary), prostate markers (e.g. PSA, PSAP, NKX3.1) +ve/-ve (+ve suggests prostate primary), PAX8 +ve/-ve (+ve suggests gyne tract or RCC)		\| IHC = [[GATA3]] -ve/+ve (commonly +ve in breast), beta-catenin +ve/-ve (nuclear staining - suggests colorectal primary), prostate markers (e.g. PSA, PSAP, NKX3.1) +ve/-ve (+ve suggests prostate primary), PAX8 +ve/-ve (+ve suggests gyne tract or RCC)
	\| EM =		\| EM =
	\| Molecular =		\| Molecular =

Michael at 03:59, 17 January 2017

2017-01-17T03:59:07Z

← Older revision		Revision as of 03:59, 17 January 2017
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	\| LMDDx = [[urothelial carcinoma]] with unusual features, [[primary adenocarcinoma of the urinary bladder]], direct extension of non-bladder primary tumour in bladder (e.g. [[prostate cancer\|prostate]], rectum, [[urachal carcinoma]])		\| LMDDx = [[urothelial carcinoma]] with unusual features, [[primary adenocarcinoma of the urinary bladder]], direct extension of non-bladder primary tumour in bladder (e.g. [[prostate cancer\|prostate]], rectum, [[urachal carcinoma]])
	\| Stains =		\| Stains =
	\| IHC = [[GATA3]] -ve (commonly +ve in breast), beta-catenin +ve (nuclear staining - suggests colorectal primary), prostate markers (e.g. PSA, PSAP, NKX3.1) +ve/-ve (+ve suggests prostate primary), PAX8 +ve/-ve (+ve suggests gyne tract or RCC)		\| IHC = [[GATA3]] -ve (commonly +ve in breast), beta-catenin +ve/-ve (nuclear staining - suggests colorectal primary), prostate markers (e.g. PSA, PSAP, NKX3.1) +ve/-ve (+ve suggests prostate primary), PAX8 +ve/-ve (+ve suggests gyne tract or RCC)
	\| EM =		\| EM =
	\| Molecular =		\| Molecular =

Michael at 03:58, 17 January 2017

2017-01-17T03:58:41Z

← Older revision		Revision as of 03:58, 17 January 2017
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			{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image = Clear cell renal cell carcinoma metastasis to bladder -- intermed mag.jpg
			\| Width =
			\| Caption = Clear cell renal cell carcinoma metastasis to urinary bladder. [[H&E stain]].
			\| Synonyms = metastasis to urinary bladder
			\| Micro =
			\| Subtypes =
			\| LMDDx = [[urothelial carcinoma]] with unusual features, [[primary adenocarcinoma of the urinary bladder]], direct extension of non-bladder primary tumour in bladder (e.g. [[prostate cancer\|prostate]], rectum, [[urachal carcinoma]])
			\| Stains =
			\| IHC = [[GATA3]] -ve (commonly +ve in breast), beta-catenin +ve (nuclear staining - suggests colorectal primary), prostate markers (e.g. PSA, PSAP, NKX3.1) +ve/-ve (+ve suggests prostate primary), PAX8 +ve/-ve (+ve suggests gyne tract or RCC)
			\| EM =
			\| Molecular =
			\| IF =
			\| Gross =
			\| Grossing =
			\| Staging =
			\| Site = [[urinary bladder]]
			\| Assdx =
			\| Syndromes =
			\| Clinicalhx = +/-history cancer
			\| Signs =
			\| Symptoms = hematuria (typical)
			\| Prevalence = rare as primary presentation (case reports)
			\| Bloodwork =
			\| Rads =
			\| Endoscopy = bladder tumour
			\| Prognosis = poor
			\| Other =
			\| ClinDDx = primary bladder cancer
			\| Tx = dependent on primary site
			}}
	'''Urinary bladder metastasis''', also '''metastasis to the bladder''', is [[cancer]] that has spread to the [[urinary bladder]] from another primary site and is discontinuous with the primary tumour.		'''Urinary bladder metastasis''', also '''metastasis to the bladder''', is [[cancer]] that has spread to the [[urinary bladder]] from another primary site and is discontinuous with the primary tumour.

Michael: /* General */

2017-01-17T03:47:22Z

General

← Older revision		Revision as of 03:47, 17 January 2017
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	*Rare - mostly case reports.		*Rare - mostly case reports.
	**[[Renal cell carcinoma]] ~ series of 11 cases.<ref name=pmid25140895>{{Cite journal \| last1 = Zhang \| first1 = M. \| last2 = Wah \| first2 = C. \| last3 = Epstein \| first3 = JI. \| title = Metastatic renal cell carcinoma to the urinary bladder: a report of 11 cases. \| journal = Am J Surg Pathol \| volume = 38 \| issue = 11 \| pages = 1516-21 \| month = Nov \| year = 2014 \| doi = 10.1097/PAS.0000000000000257 \| PMID = 25140895 }}</ref>		**[[Renal cell carcinoma]] ~ series of 11 cases.<ref name=pmid25140895>{{Cite journal \| last1 = Zhang \| first1 = M. \| last2 = Wah \| first2 = C. \| last3 = Epstein \| first3 = JI. \| title = Metastatic renal cell carcinoma to the urinary bladder: a report of 11 cases. \| journal = Am J Surg Pathol \| volume = 38 \| issue = 11 \| pages = 1516-21 \| month = Nov \| year = 2014 \| doi = 10.1097/PAS.0000000000000257 \| PMID = 25140895 }}</ref>
			**Breast primary - small series<ref name=pmid26437333>{{Cite journal \| last1 = Avargues \| first1 = A. \| last2 = Luján \| first2 = S. \| last3 = Palomar \| first3 = L. \| last4 = Rogel \| first4 = R. \| last5 = Broseta \| first5 = E. \| last6 = Boronat \| first6 = F. \| title = [Metastatic urinary bladder involvement in breast cancer]. \| journal = Arch Esp Urol \| volume = 68 \| issue = 8 \| pages = 676-8 \| month = Oct \| year = 2015 \| doi = \| PMID = 26437333 }}</ref> and case reports.<ref name=pmid27047651>{{Cite journal \| last1 = Al Ibraheemi \| first1 = AA. \| title = Case report of metastatic invasive breast lobular carcinoma to the urinary bladder. \| journal = Int J Hematol Oncol Stem Cell Res \| volume = 10 \| issue = 1 \| pages = 51-5 \| month = Jan \| year = 2016 \| doi = \| PMID = 27047651 }}</ref><ref name=pmid24088591>{{Cite journal \| last1 = Wong \| first1 = MH. \| last2 = Yiu \| first2 = MK. \| last3 = Ho \| first3 = KL. \| title = Metastatic carcinoma of breast in the urinary bladder. \| journal = Hong Kong Med J \| volume = 19 \| issue = 5 \| pages = 455-7 \| month = Oct \| year = 2013 \| doi = \| PMID = 24088591 }}</ref>

	A 2007 review of the literature found:<ref name=pmid17324324>{{Cite journal \| last1 = Velcheti \| first1 = V. \| last2 = Govindan \| first2 = R. \| title = Metastatic cancer involving bladder: a review. \| journal = Can J Urol \| volume = 14 \| issue = 1 \| pages = 3443-8 \| month = Feb \| year = 2007 \| doi = \| PMID = 17324324 }}</ref>		A 2007 review of the literature found:<ref name=pmid17324324>{{Cite journal \| last1 = Velcheti \| first1 = V. \| last2 = Govindan \| first2 = R. \| title = Metastatic cancer involving bladder: a review. \| journal = Can J Urol \| volume = 14 \| issue = 1 \| pages = 3443-8 \| month = Feb \| year = 2007 \| doi = \| PMID = 17324324 }}</ref>

Michael: /* General */

2017-01-17T03:41:49Z

General

← Older revision		Revision as of 03:41, 17 January 2017
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	A 2007 review of the literature found:<ref name=pmid17324324>{{Cite journal \| last1 = Velcheti \| first1 = V. \| last2 = Govindan \| first2 = R. \| title = Metastatic cancer involving bladder: a review. \| journal = Can J Urol \| volume = 14 \| issue = 1 \| pages = 3443-8 \| month = Feb \| year = 2007 \| doi = \| PMID = 17324324 }}</ref>		A 2007 review of the literature found:<ref name=pmid17324324>{{Cite journal \| last1 = Velcheti \| first1 = V. \| last2 = Govindan \| first2 = R. \| title = Metastatic cancer involving bladder: a review. \| journal = Can J Urol \| volume = 14 \| issue = 1 \| pages = 3443-8 \| month = Feb \| year = 2007 \| doi = \| PMID = 17324324 }}</ref>
	*264 reported cases from 1953 to June 2005.		*264 reported cases from 1953 to June 2005 - most from GU tract and the colorectum.
			**Distant site includes [[breast cancer\|breast]], stomach and melanoma.

	==Microscopic==		==Microscopic==

Michael at 03:36, 17 January 2017

2017-01-17T03:36:32Z

← Older revision		Revision as of 03:36, 17 January 2017
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	*Rare - mostly case reports.		*Rare - mostly case reports.
	**[[Renal cell carcinoma]] ~ series of 11 cases.<ref name=pmid25140895>{{Cite journal \| last1 = Zhang \| first1 = M. \| last2 = Wah \| first2 = C. \| last3 = Epstein \| first3 = JI. \| title = Metastatic renal cell carcinoma to the urinary bladder: a report of 11 cases. \| journal = Am J Surg Pathol \| volume = 38 \| issue = 11 \| pages = 1516-21 \| month = Nov \| year = 2014 \| doi = 10.1097/PAS.0000000000000257 \| PMID = 25140895 }}</ref>		**[[Renal cell carcinoma]] ~ series of 11 cases.<ref name=pmid25140895>{{Cite journal \| last1 = Zhang \| first1 = M. \| last2 = Wah \| first2 = C. \| last3 = Epstein \| first3 = JI. \| title = Metastatic renal cell carcinoma to the urinary bladder: a report of 11 cases. \| journal = Am J Surg Pathol \| volume = 38 \| issue = 11 \| pages = 1516-21 \| month = Nov \| year = 2014 \| doi = 10.1097/PAS.0000000000000257 \| PMID = 25140895 }}</ref>

			A 2007 review of the literature found:<ref name=pmid17324324>{{Cite journal \| last1 = Velcheti \| first1 = V. \| last2 = Govindan \| first2 = R. \| title = Metastatic cancer involving bladder: a review. \| journal = Can J Urol \| volume = 14 \| issue = 1 \| pages = 3443-8 \| month = Feb \| year = 2007 \| doi = \| PMID = 17324324 }}</ref>
			*264 reported cases from 1953 to June 2005.

	==Microscopic==		==Microscopic==
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	*[[Primary adenocarcinoma of the urinary bladder]].		*[[Primary adenocarcinoma of the urinary bladder]].
	*[[Urachal carcinoma]].		*[[Urachal carcinoma]].
	*Direct extension of primary tumour from other primary site, e.g. prostate, rectum.		*Direct extension of primary tumour from other primary site, e.g. [[prostate cancer\|prostate]], rectum.

	===Images===		===Images===

Michael at 03:31, 17 January 2017

2017-01-17T03:31:00Z

← Older revision		Revision as of 03:31, 17 January 2017
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	'''Urinary bladder metastasis''' is [[cancer]] that has spread to the [[urinary bladder]] from another primary site and is discontinuous with the primary tumour.		'''Urinary bladder metastasis''', also '''metastasis to the bladder''', is [[cancer]] that has spread to the [[urinary bladder]] from another primary site and is discontinuous with the primary tumour.

	==General==		==General==
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	Image: Clear cell renal cell carcinoma metastasis to bladder -- high mag.jpg \| CCRCC in bladder - high mag. (WC)		Image: Clear cell renal cell carcinoma metastasis to bladder -- high mag.jpg \| CCRCC in bladder - high mag. (WC)
	</gallery>		</gallery>
			==See also==
			*[[Metastasis]].

	==References==		==References==
	{{Reflist\|1}}		{{Reflist\|1}}

Michael: +images

2017-01-17T03:29:42Z

+images

← Older revision		Revision as of 03:29, 17 January 2017
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	*Direct extension of primary tumour from other primary site, e.g. prostate, rectum.		*Direct extension of primary tumour from other primary site, e.g. prostate, rectum.

			===Images===
			<gallery>
			Image: Clear cell renal cell carcinoma metastasis to bladder -- very low mag.jpg \| CCRCC in bladder - very low mag. (WC)
			Image: Clear cell renal cell carcinoma metastasis to bladder -- low mag.jpg \| CCRCC in bladder - low mag. (WC)
			Image: Clear cell renal cell carcinoma metastasis to bladder -- intermed mag.jpg \| CCRCC in bladder - intermed. mag. (WC)
			Image: Clear cell renal cell carcinoma metastasis to bladder -- high mag.jpg \| CCRCC in bladder - high mag. (WC)
			</gallery>
	==References==		==References==
	{{Reflist\|1}}		{{Reflist\|1}}

Michael: /* Microscopic */

2017-01-17T03:29:07Z

Microscopic

← Older revision		Revision as of 03:29, 17 January 2017
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	DDx:		DDx:
	*[[Urothelial carcinoma]] with unusual features.		*[[Urothelial carcinoma]] with unusual features.
	*[[Primary adenocarcinoma of the bladder]].		*[[Primary adenocarcinoma of the urinary bladder]].
	*[[Urachal carcinoma]].		*[[Urachal carcinoma]].
	*Direct extension of primary tumour from other primary site, e.g. prostate, rectum.		*Direct extension of primary tumour from other primary site, e.g. prostate, rectum.