Urachal carcinoma - Revision history

Michael: /* IHC */

2022-08-04T14:54:33Z

IHC

← Older revision		Revision as of 14:54, 4 August 2022
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	==IHC==		==IHC==
	Features:<ref name=pmid19252435>{{Cite journal \| last1 = Gopalan \| first1 = A. \| last2 = Sharp \| first2 = DS. \| last3 = Fine \| first3 = SW. \| last4 = Tickoo \| first4 = SK. \| last5 = Herr \| first5 = HW. \| last6 = Reuter \| first6 = VE. \| last7 = Olgac \| first7 = S. \| title = Urachal carcinoma: a clinicopathologic analysis of 24 cases with outcome correlation. \| journal = Am J Surg Pathol \| volume = 33 \| issue = 5 \| pages = 659-68 \| month = May \| year = 2009 \| doi = 10.1097/PAS.0b013e31819aa4ae \| PMID = 19252435 }}</ref>		Features:<ref name=pmid19252435>{{Cite journal \| last1 = Gopalan \| first1 = A. \| last2 = Sharp \| first2 = DS. \| last3 = Fine \| first3 = SW. \| last4 = Tickoo \| first4 = SK. \| last5 = Herr \| first5 = HW. \| last6 = Reuter \| first6 = VE. \| last7 = Olgac \| first7 = S. \| title = Urachal carcinoma: a clinicopathologic analysis of 24 cases with outcome correlation. \| journal = Am J Surg Pathol \| volume = 33 \| issue = 5 \| pages = 659-68 \| month = May \| year = 2009 \| doi = 10.1097/PAS.0b013e31819aa4ae \| PMID = 19252435 }}</ref>
	*CK20 +ve.		*[[CK20]] +ve.
	*CK7 +ve/-ve.		*[[CK7]] +ve/-ve.
	*CK34betaE12 +ve/-ve.		*[[CK34betaE12]] +ve/-ve.
	*Beta-catenin -- usu cytoplasmic/membranous +ve.		*Beta-catenin -- usu cytoplasmic/membranous +ve.

Michael: tweak

2021-03-05T15:48:32Z

tweak

← Older revision		Revision as of 15:48, 5 March 2021
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	\| Micro = atypical cells - usually gland forming, +/-mucinous component, +/-signet rings		\| Micro = atypical cells - usually gland forming, +/-mucinous component, +/-signet rings
	\| Subtypes = enteric, mucinous, signet ring		\| Subtypes = enteric, mucinous, signet ring
	\| LMDDx = [[adenocarcinoma of the urinary bladder]], invasive [[urothelial carcinoma]] with glandular differentiation, [[metastatic]] adenocarcinoma		\| LMDDx = [[adenocarcinoma of the urinary bladder]], invasive [[urothelial carcinoma]] with glandular differentiation, [[metastatic]] adenocarcinoma (especially colorectal)
	\| Stains =		\| Stains =
	\| IHC = CK20 +ve, beta-catenin +ve (non-nuclear), p63 -ve, CK34betaE12 +ve		\| IHC = CK20 +ve, beta-catenin +ve (non-nuclear), p63 -ve, CK34betaE12 +ve
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	\| Assdx =		\| Assdx =
	\| Syndromes =		\| Syndromes =
	\| Clinicalhx =		\| Clinicalhx = no prior urothelial carcinoma
	\| Signs = +/-hematuria		\| Signs = +/-hematuria
	\| Symptoms =		\| Symptoms =
	\| Prevalence = very rare		\| Prevalence = very rare
	\| Bloodwork =		\| Bloodwork =
	\| Rads =		\| Rads = lesion of bladder dome/anterior bladder, lesion centered in wall of bladder (rather than mucosa)
	\| Endoscopy =		\| Endoscopy =
	\| Prognosis = usually poor		\| Prognosis = usually poor
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	}}		}}
	'''Urachal carcinoma''' is an uncommon [[cancer\|malignant tumour]] that arises from the urachus. Most urachal carcinomas are ''[[adenocarcinoma]]s''.		'''Urachal carcinoma''' is an uncommon [[cancer\|malignant tumour]] that arises from the urachus. Most urachal carcinomas are ''[[adenocarcinoma]]s''.

			The diagnosis is a clinicopathologic diagnosis - one needs imaging to make it.<ref name=Ref_Amin2-143>{{Ref Amin\|2-143}}</ref>

	==General==		==General==

Michael: /* Sign out */

2021-03-05T15:45:03Z

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← Older revision		Revision as of 15:45, 5 March 2021
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	</pre>		</pre>

	~~Note:~~		===Staging===
	*The ~~diagnosis is a clinicopathologic diagnosis - one needs imaging to make it~~.~~<ref name=Ref_Amin2-143>{{Ref Amin\|~~2~~-143}}</ref>~~		*The CAP urinary bladder synoptic, as per v4.0.2.0, should ''not'' be used.
	*May be [[cancer staging\|staged]] with the ''Sheldon system''.<ref name=pmid22901574>{{Cite journal \| last1 = Bruins \| first1 = HM. \| last2 = Visser \| first2 = O. \| last3 = Ploeg \| first3 = M. \| last4 = Hulsbergen-van de Kaa \| first4 = CA. \| last5 = Kiemeney \| first5 = LA. \| last6 = Witjes \| first6 = JA. \| title = The clinical epidemiology of urachal carcinoma: results of a large, population based study. \| journal = J Urol \| volume = 188 \| issue = 4 \| pages = 1102-7 \| month = Oct \| year = 2012 \| doi = 10.1016/j.juro.2012.06.020 \| PMID = 22901574 }}</ref>		*May be [[cancer staging\|staged]] with the ''Sheldon system''.<ref name=pmid22901574>{{Cite journal \| last1 = Bruins \| first1 = HM. \| last2 = Visser \| first2 = O. \| last3 = Ploeg \| first3 = M. \| last4 = Hulsbergen-van de Kaa \| first4 = CA. \| last5 = Kiemeney \| first5 = LA. \| last6 = Witjes \| first6 = JA. \| title = The clinical epidemiology of urachal carcinoma: results of a large, population based study. \| journal = J Urol \| volume = 188 \| issue = 4 \| pages = 1102-7 \| month = Oct \| year = 2012 \| doi = 10.1016/j.juro.2012.06.020 \| PMID = 22901574 }}</ref>

	===Sheldon staging system===		====Sheldon staging system====
	Staging as per Sheldon ''et al.'':<ref name=pmid19252435>{{Cite journal \| last1 = Gopalan \| first1 = A. \| last2 = Sharp \| first2 = DS. \| last3 = Fine \| first3 = SW. \| last4 = Tickoo \| first4 = SK. \| last5 = Herr \| first5 = HW. \| last6 = Reuter \| first6 = VE. \| last7 = Olgac \| first7 = S. \| title = Urachal carcinoma: a clinicopathologic analysis of 24 cases with outcome correlation. \| journal = Am J Surg Pathol \| volume = 33 \| issue = 5 \| pages = 659-68 \| month = May \| year = 2009 \| doi = 10.1097/PAS.0b013e31819aa4ae \| PMID = 19252435 }}</ref><ref name=pmid6361280>{{Cite journal \| last1 = Sheldon \| first1 = CA. \| last2 = Clayman \| first2 = RV. \| last3 = Gonzalez \| first3 = R. \| last4 = Williams \| first4 = RD. \| last5 = Fraley \| first5 = EE. \| title = Malignant urachal lesions. \| journal = J Urol \| volume = 131 \| issue = 1 \| pages = 1-8 \| month = Jan \| year = 1984 \| doi = \| PMID = 6361280 }}</ref>		Staging as per Sheldon ''et al.'':<ref name=pmid19252435>{{Cite journal \| last1 = Gopalan \| first1 = A. \| last2 = Sharp \| first2 = DS. \| last3 = Fine \| first3 = SW. \| last4 = Tickoo \| first4 = SK. \| last5 = Herr \| first5 = HW. \| last6 = Reuter \| first6 = VE. \| last7 = Olgac \| first7 = S. \| title = Urachal carcinoma: a clinicopathologic analysis of 24 cases with outcome correlation. \| journal = Am J Surg Pathol \| volume = 33 \| issue = 5 \| pages = 659-68 \| month = May \| year = 2009 \| doi = 10.1097/PAS.0b013e31819aa4ae \| PMID = 19252435 }}</ref><ref name=pmid6361280>{{Cite journal \| last1 = Sheldon \| first1 = CA. \| last2 = Clayman \| first2 = RV. \| last3 = Gonzalez \| first3 = R. \| last4 = Williams \| first4 = RD. \| last5 = Fraley \| first5 = EE. \| title = Malignant urachal lesions. \| journal = J Urol \| volume = 131 \| issue = 1 \| pages = 1-8 \| month = Jan \| year = 1984 \| doi = \| PMID = 6361280 }}</ref>
	*pT1 - confined to urachal mucosa.		*pT1 - confined to urachal mucosa.

Michael: /* Sign out */

2021-03-05T15:40:45Z

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← Older revision		Revision as of 15:40, 5 March 2021
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	==Sign out==		==Sign out==
			<pre>
			Mass, Urachus, Resection:
			- ADENOCARCINOMA, consistent with urachal primary, see comment.
			-- Margins clear.

			Comment:
			The sections show malignant cells within the perivesicular soft tissue arranged in nests and glands with necrosis. The lesion center is within the bladder wall, rather than at the mucosa. The sampled bladder mucosa is within normal limits.

			The tumour stains as follows:
			POSITIVE: CDX2 (focal, moderate nuclear), CK20 (focal, moderate membranous).
			NEGATIVE: CK7, p63, CK5/6, GATA3, beta-catenin (membranous only, nuclei negative).

			The histomorphology, immunoprofile and imaging are compatible with a primary urachal adenocarcinoma.

			The morphology and immunoprofile of urachal adenocarcinoma overlaps with primary adenocarcinoma of the bladder and somewhat with colorectal adenocarcinoma. Primary adenocarcinoma of the bladder is unlikely as the sampled urothelium is benign, the lesion is centered within the wall and no history of bladder tumours was found. Metastatic colorectal cancer seems unlikely from the clinical information available.

			The CAP bladder synoptic is not applicable to urachal carcinoma.

			In the context of the "Sheldon Staging System" for urachal carcinoma, this case would be pT3a.
			</pre>

			Note:
	*The diagnosis is a clinicopathologic diagnosis - one needs imaging to make it.<ref name=Ref_Amin2-143>{{Ref Amin\|2-143}}</ref>		*The diagnosis is a clinicopathologic diagnosis - one needs imaging to make it.<ref name=Ref_Amin2-143>{{Ref Amin\|2-143}}</ref>
	*May be [[cancer staging\|staged]] with the ''Sheldon system''.<ref name=pmid22901574>{{Cite journal \| last1 = Bruins \| first1 = HM. \| last2 = Visser \| first2 = O. \| last3 = Ploeg \| first3 = M. \| last4 = Hulsbergen-van de Kaa \| first4 = CA. \| last5 = Kiemeney \| first5 = LA. \| last6 = Witjes \| first6 = JA. \| title = The clinical epidemiology of urachal carcinoma: results of a large, population based study. \| journal = J Urol \| volume = 188 \| issue = 4 \| pages = 1102-7 \| month = Oct \| year = 2012 \| doi = 10.1016/j.juro.2012.06.020 \| PMID = 22901574 }}</ref>		*May be [[cancer staging\|staged]] with the ''Sheldon system''.<ref name=pmid22901574>{{Cite journal \| last1 = Bruins \| first1 = HM. \| last2 = Visser \| first2 = O. \| last3 = Ploeg \| first3 = M. \| last4 = Hulsbergen-van de Kaa \| first4 = CA. \| last5 = Kiemeney \| first5 = LA. \| last6 = Witjes \| first6 = JA. \| title = The clinical epidemiology of urachal carcinoma: results of a large, population based study. \| journal = J Urol \| volume = 188 \| issue = 4 \| pages = 1102-7 \| month = Oct \| year = 2012 \| doi = 10.1016/j.juro.2012.06.020 \| PMID = 22901574 }}</ref>

Michael: /* Microscopic */

2015-02-20T19:36:24Z

Microscopic

← Older revision		Revision as of 19:36, 20 February 2015
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	*Invasive [[urothelial carcinoma]] with glandular differentiation.		*Invasive [[urothelial carcinoma]] with glandular differentiation.
	*[[Metastatic]] adenocarcinoma/[[adenocarcinoma]] extending from another structure, e.g. [[colorectal adenocarcinoma]].		*[[Metastatic]] adenocarcinoma/[[adenocarcinoma]] extending from another structure, e.g. [[colorectal adenocarcinoma]].
			*Villous adenoma of the urachus<ref>{{Cite journal \| last1 = Joniau \| first1 = S. \| last2 = Lerut \| first2 = E. \| last3 = Van Poppel \| first3 = H. \| title = A Giant Mucinous Adenocarcinoma Arising within a Villous Adenoma of the Urachus: Case Report and Review of the Literature. \| journal = Case Rep Med \| volume = 2009 \| issue = \| pages = 818646 \| month = \| year = 2009 \| doi = 10.1155/2009/818646 \| PMID = 20182635 }}</ref> - non-invasive.

	===Patterns===		===Patterns===

Michael: /* Microscopic */ fix typo

2014-12-30T07:15:49Z

Microscopic: fix typo

← Older revision		Revision as of 07:15, 30 December 2014
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	*Usually gland forming, i.e. adenocarcinoma.		*Usually gland forming, i.e. adenocarcinoma.
	*+/-Mucinous component.		*+/-Mucinous component.
	Features making it ~~urothelial~~ carcinoma (modified Sheldon criteria) - all required:<ref name=pmid22301493>{{Cite journal \| last1 = Paner \| first1 = GP. \| last2 = Barkan \| first2 = GA. \| last3 = Mehta \| first3 = V. \| last4 = Sirintrapun \| first4 = SJ. \| last5 = Tsuzuki \| first5 = T. \| last6 = Sebo \| first6 = TJ. \| last7 = Jimenez \| first7 = RE. \| title = Urachal carcinomas of the nonglandular type: salient features and considerations in pathologic diagnosis. \| journal = Am J Surg Pathol \| volume = 36 \| issue = 3 \| pages = 432-42 \| month = Mar \| year = 2012 \| doi = 10.1097/PAS.0b013e31823fe49c \| PMID = 22301493 }}</ref>		Features making it ''urachal carcinoma'' (modified Sheldon criteria) - all required:<ref name=pmid22301493>{{Cite journal \| last1 = Paner \| first1 = GP. \| last2 = Barkan \| first2 = GA. \| last3 = Mehta \| first3 = V. \| last4 = Sirintrapun \| first4 = SJ. \| last5 = Tsuzuki \| first5 = T. \| last6 = Sebo \| first6 = TJ. \| last7 = Jimenez \| first7 = RE. \| title = Urachal carcinomas of the nonglandular type: salient features and considerations in pathologic diagnosis. \| journal = Am J Surg Pathol \| volume = 36 \| issue = 3 \| pages = 432-42 \| month = Mar \| year = 2012 \| doi = 10.1097/PAS.0b013e31823fe49c \| PMID = 22301493 }}</ref>
	#Located in bladder dome or anterior wall. †		#Located in bladder dome or anterior wall. †
	#Centered on bladder wall (as opposed to the mucosa).		#Centered on bladder wall (as opposed to the mucosa).

Michael: /* Sign out */

2014-11-24T06:22:29Z

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← Older revision		Revision as of 06:22, 24 November 2014
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	===Sheldon staging system===		===Sheldon staging system===
	Staging as Sheldon ''et al.'':<ref name=pmid19252435>{{Cite journal \| last1 = Gopalan \| first1 = A. \| last2 = Sharp \| first2 = DS. \| last3 = Fine \| first3 = SW. \| last4 = Tickoo \| first4 = SK. \| last5 = Herr \| first5 = HW. \| last6 = Reuter \| first6 = VE. \| last7 = Olgac \| first7 = S. \| title = Urachal carcinoma: a clinicopathologic analysis of 24 cases with outcome correlation. \| journal = Am J Surg Pathol \| volume = 33 \| issue = 5 \| pages = 659-68 \| month = May \| year = 2009 \| doi = 10.1097/PAS.0b013e31819aa4ae \| PMID = 19252435 }}</ref><ref name=pmid6361280>{{Cite journal \| last1 = Sheldon \| first1 = CA. \| last2 = Clayman \| first2 = RV. \| last3 = Gonzalez \| first3 = R. \| last4 = Williams \| first4 = RD. \| last5 = Fraley \| first5 = EE. \| title = Malignant urachal lesions. \| journal = J Urol \| volume = 131 \| issue = 1 \| pages = 1-8 \| month = Jan \| year = 1984 \| doi = \| PMID = 6361280 }}</ref>		Staging as per Sheldon ''et al.'':<ref name=pmid19252435>{{Cite journal \| last1 = Gopalan \| first1 = A. \| last2 = Sharp \| first2 = DS. \| last3 = Fine \| first3 = SW. \| last4 = Tickoo \| first4 = SK. \| last5 = Herr \| first5 = HW. \| last6 = Reuter \| first6 = VE. \| last7 = Olgac \| first7 = S. \| title = Urachal carcinoma: a clinicopathologic analysis of 24 cases with outcome correlation. \| journal = Am J Surg Pathol \| volume = 33 \| issue = 5 \| pages = 659-68 \| month = May \| year = 2009 \| doi = 10.1097/PAS.0b013e31819aa4ae \| PMID = 19252435 }}</ref><ref name=pmid6361280>{{Cite journal \| last1 = Sheldon \| first1 = CA. \| last2 = Clayman \| first2 = RV. \| last3 = Gonzalez \| first3 = R. \| last4 = Williams \| first4 = RD. \| last5 = Fraley \| first5 = EE. \| title = Malignant urachal lesions. \| journal = J Urol \| volume = 131 \| issue = 1 \| pages = 1-8 \| month = Jan \| year = 1984 \| doi = \| PMID = 6361280 }}</ref>
	*pT1 - confined to urachal mucosa.		*pT1 - confined to urachal mucosa.
	*pT2 - confined to the urachus.		*pT2 - confined to the urachus.

Michael: /* General */

2014-11-24T06:21:27Z

General

← Older revision		Revision as of 06:21, 24 November 2014
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	*Very rare<ref name=pmid16826585>{{Cite journal \| last1 = Ashley \| first1 = RA. \| last2 = Inman \| first2 = BA. \| last3 = Sebo \| first3 = TJ. \| last4 = Leibovich \| first4 = BC. \| last5 = Blute \| first5 = ML. \| last6 = Kwon \| first6 = ED. \| last7 = Zincke \| first7 = H. \| title = Urachal carcinoma: clinicopathologic features and long-term outcomes of an aggressive malignancy. \| journal = Cancer \| volume = 107 \| issue = 4 \| pages = 712-20 \| month = Aug \| year = 2006 \| doi = 10.1002/cncr.22060 \| PMID = 16826585 }}</ref>~ 0.2% of bladder cancers.<ref name=pmid22901574>{{Cite journal \| last1 = Bruins \| first1 = HM. \| last2 = Visser \| first2 = O. \| last3 = Ploeg \| first3 = M. \| last4 = Hulsbergen-van de Kaa \| first4 = CA. \| last5 = Kiemeney \| first5 = LA. \| last6 = Witjes \| first6 = JA. \| title = The clinical epidemiology of urachal carcinoma: results of a large, population based study. \| journal = J Urol \| volume = 188 \| issue = 4 \| pages = 1102-7 \| month = Oct \| year = 2012 \| doi = 10.1016/j.juro.2012.06.020 \| PMID = 22901574 }}</ref>		*Very rare<ref name=pmid16826585>{{Cite journal \| last1 = Ashley \| first1 = RA. \| last2 = Inman \| first2 = BA. \| last3 = Sebo \| first3 = TJ. \| last4 = Leibovich \| first4 = BC. \| last5 = Blute \| first5 = ML. \| last6 = Kwon \| first6 = ED. \| last7 = Zincke \| first7 = H. \| title = Urachal carcinoma: clinicopathologic features and long-term outcomes of an aggressive malignancy. \| journal = Cancer \| volume = 107 \| issue = 4 \| pages = 712-20 \| month = Aug \| year = 2006 \| doi = 10.1002/cncr.22060 \| PMID = 16826585 }}</ref>~ 0.2% of bladder cancers.<ref name=pmid22901574>{{Cite journal \| last1 = Bruins \| first1 = HM. \| last2 = Visser \| first2 = O. \| last3 = Ploeg \| first3 = M. \| last4 = Hulsbergen-van de Kaa \| first4 = CA. \| last5 = Kiemeney \| first5 = LA. \| last6 = Witjes \| first6 = JA. \| title = The clinical epidemiology of urachal carcinoma: results of a large, population based study. \| journal = J Urol \| volume = 188 \| issue = 4 \| pages = 1102-7 \| month = Oct \| year = 2012 \| doi = 10.1016/j.juro.2012.06.020 \| PMID = 22901574 }}</ref>
	*Often younger <55 years-old.		*Often younger <55 years-old.
	*Poor prognosis<ref name=pmid24136277/> - especially for high Sheldon stage.<ref name=pmid19252435>{{Cite journal \| last1 = Gopalan \| first1 = A. \| last2 = Sharp \| first2 = DS. \| last3 = Fine \| first3 = SW. \| last4 = Tickoo \| first4 = SK. \| last5 = Herr \| first5 = HW. \| last6 = Reuter \| first6 = VE. \| last7 = Olgac \| first7 = S. \| title = Urachal carcinoma: a clinicopathologic analysis of 24 cases with outcome correlation. \| journal = Am J Surg Pathol \| volume = 33 \| issue = 5 \| pages = 659-68 \| month = May \| year = 2009 \| doi = 10.1097/PAS.0b013e31819aa4ae \| PMID = 19252435 }}</ref>		*Poor prognosis<ref name=pmid24136277/> - especially for high [[Sheldon stage]].<ref name=pmid19252435>{{Cite journal \| last1 = Gopalan \| first1 = A. \| last2 = Sharp \| first2 = DS. \| last3 = Fine \| first3 = SW. \| last4 = Tickoo \| first4 = SK. \| last5 = Herr \| first5 = HW. \| last6 = Reuter \| first6 = VE. \| last7 = Olgac \| first7 = S. \| title = Urachal carcinoma: a clinicopathologic analysis of 24 cases with outcome correlation. \| journal = Am J Surg Pathol \| volume = 33 \| issue = 5 \| pages = 659-68 \| month = May \| year = 2009 \| doi = 10.1097/PAS.0b013e31819aa4ae \| PMID = 19252435 }}</ref>

	Clinical:		Clinical:

Michael: +more images

2014-11-24T06:20:11Z

+more images

← Older revision		Revision as of 06:20, 24 November 2014
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	Clinical:		Clinical:
	*Hematuria - classic ~~presenation~~.<ref name=pmid24136277>{{Cite journal \| last1 = Shao \| first1 = GJ. \| last2 = Cai \| first2 = L. \| last3 = Li \| first3 = XS. \| last4 = Song \| first4 = G. \| last5 = Li \| first5 = XY. \| last6 = He \| first6 = ZS. \| last7 = Zhou \| first7 = LQ. \| title = [Urachal carcinoma: experience of a clinical center within 30 years]. \| journal = Beijing Da Xue Xue Bao \| volume = 45 \| issue = 5 \| pages = 774-8 \| month = Oct \| year = 2013 \| doi = \| PMID = 24136277 }}</ref>		*Hematuria - classic presentation.<ref name=pmid24136277>{{Cite journal \| last1 = Shao \| first1 = GJ. \| last2 = Cai \| first2 = L. \| last3 = Li \| first3 = XS. \| last4 = Song \| first4 = G. \| last5 = Li \| first5 = XY. \| last6 = He \| first6 = ZS. \| last7 = Zhou \| first7 = LQ. \| title = [Urachal carcinoma: experience of a clinical center within 30 years]. \| journal = Beijing Da Xue Xue Bao \| volume = 45 \| issue = 5 \| pages = 774-8 \| month = Oct \| year = 2013 \| doi = \| PMID = 24136277 }}</ref>

	Treatment:		Treatment:
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	===Images===		===Images===
	<gallery>		<gallery>
	Image:~~Urachal_carcinoma_~~-~~_very_low_mag~~.jpg \| UC - very low mag. (WC)		Image: Urachal carcinoma - very low mag.jpg \| UC - very low mag. (WC/Nephron)
	Image:~~Urachal_carcinoma_~~-~~_low_mag~~.jpg \| UC - low mag. (WC)		Image: Urachal carcinoma - low mag.jpg \| UC - low mag. (WC/Nephron)
	Image:~~Urachal_carcinoma_~~-~~_high_mag~~.jpg \| UC - high mag. (WC)		Image: Urachal carcinoma - intermed mag.jpg \| UC - intermed mag. (WC/Nephron)
			Image: Urachal carcinoma - high mag.jpg \| UC - high mag. (WC/Nephron)
			Image: Urachal carcinoma - very high mag.jpg \| UC - very high mag. (WC/Nephron)
	</gallery>		</gallery>

Michael: /* Microscopic */

2014-11-24T06:15:49Z

Microscopic

← Older revision		Revision as of 06:15, 24 November 2014
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	*[[Adenocarcinoma of the urinary bladder]].		*[[Adenocarcinoma of the urinary bladder]].
	*Invasive [[urothelial carcinoma]] with glandular differentiation.		*Invasive [[urothelial carcinoma]] with glandular differentiation.
	*[[Metastatic ~~adenocarcinoma~~]]/adenocarcinoma extending from another structure, e.g. [[colorectal adenocarcinoma]].		*[[Metastatic]] adenocarcinoma/[[adenocarcinoma]] extending from another structure, e.g. [[colorectal adenocarcinoma]].

	===Patterns===		===Patterns===