TFE3 - Revision history

Michael at 03:49, 16 October 2023

2023-10-16T03:49:21Z

← Older revision		Revision as of 03:49, 16 October 2023
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	*[[Alveolar soft part sarcoma]].		*[[Alveolar soft part sarcoma]].
	* YAP-TFE3 translocated [[epithelioid hemangioendothelioma]]		* YAP-TFE3 translocated [[epithelioid hemangioendothelioma]]
	*[[Epithelioid angiomyolipoma]]		*[[Epithelioid angiomyolipoma]].
	*[[Granular cell ~~tumor~~]]<ref>{{cite journal \|authors=Chamberlain BK, McClain CM, Gonzalez RS, Coffin CM, Cates JM \|title=Alveolar soft part sarcoma and granular cell tumor: an immunohistochemical comparison study \|journal=Hum. Pathol. \|volume=45 \|issue=5 \|pages=1039–44 \|date=May 2014 \|pmid=24746209 \|doi=10.1016/j.humpath.2013.12.021 \|url=}}</ref>		*[[Granular cell tumour]].<ref>{{cite journal \|authors=Chamberlain BK, McClain CM, Gonzalez RS, Coffin CM, Cates JM \|title=Alveolar soft part sarcoma and granular cell tumor: an immunohistochemical comparison study \|journal=Hum. Pathol. \|volume=45 \|issue=5 \|pages=1039–44 \|date=May 2014 \|pmid=24746209 \|doi=10.1016/j.humpath.2013.12.021 \|url=}}</ref>

	==See also==		==See also==

Michael at 03:48, 16 October 2023

2023-10-16T03:48:21Z

← Older revision		Revision as of 03:48, 16 October 2023
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	}}		}}
	'''TFE3''' is an [[immunostain]] used in [[uropathology]] and [[soft tissue pathology]].		'''TFE3''' is an [[immunostain]] used in [[uropathology]] and [[soft tissue pathology]].

			The reliability of the immunostain for detecting TFE3 rearrangments has been questioned by at least one study.<ref name=pmid30851332>{{cite journal \|vauthors=Sharain RF, Gown AM, Greipp PT, Folpe AL \|title=Immunohistochemistry for TFE3 lacks specificity and sensitivity in the diagnosis of TFE3-rearranged neoplasms: a comparative, 2-laboratory study \|journal=Hum Pathol \|volume=87 \|issue= \|pages=65–74 \|date=May 2019 \|pmid=30851332 \|doi=10.1016/j.humpath.2019.02.008 \|url=}}</ref>

	==Negative==		==Negative==

Michael: vauthors

2020-05-24T20:26:26Z

vauthors

← Older revision		Revision as of 20:26, 24 May 2020
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	* YAP-TFE3 translocated [[epithelioid hemangioendothelioma]]		* YAP-TFE3 translocated [[epithelioid hemangioendothelioma]]
	*[[Epithelioid angiomyolipoma]]		*[[Epithelioid angiomyolipoma]]
	*[[Granular cell tumor]]<ref>{{cite journal \|~~vauthors~~=Chamberlain BK, McClain CM, Gonzalez RS, Coffin CM, Cates JM \|title=Alveolar soft part sarcoma and granular cell tumor: an immunohistochemical comparison study \|journal=Hum. Pathol. \|volume=45 \|issue=5 \|pages=1039–44 \|date=May 2014 \|pmid=24746209 \|doi=10.1016/j.humpath.2013.12.021 \|url=}}</ref>		*[[Granular cell tumor]]<ref>{{cite journal \|authors=Chamberlain BK, McClain CM, Gonzalez RS, Coffin CM, Cates JM \|title=Alveolar soft part sarcoma and granular cell tumor: an immunohistochemical comparison study \|journal=Hum. Pathol. \|volume=45 \|issue=5 \|pages=1039–44 \|date=May 2014 \|pmid=24746209 \|doi=10.1016/j.humpath.2013.12.021 \|url=}}</ref>

	==See also==		==See also==

Mark: other tumours

2020-02-06T21:27:36Z

other tumours

← Older revision		Revision as of 21:27, 6 February 2020
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	*[[Xp11.2 translocation carcinoma]].		*[[Xp11.2 translocation carcinoma]].
	*[[Alveolar soft part sarcoma]].		*[[Alveolar soft part sarcoma]].
			* YAP-TFE3 translocated [[epithelioid hemangioendothelioma]]
			*[[Epithelioid angiomyolipoma]]
			*[[Granular cell tumor]]<ref>{{cite journal \|vauthors=Chamberlain BK, McClain CM, Gonzalez RS, Coffin CM, Cates JM \|title=Alveolar soft part sarcoma and granular cell tumor: an immunohistochemical comparison study \|journal=Hum. Pathol. \|volume=45 \|issue=5 \|pages=1039–44 \|date=May 2014 \|pmid=24746209 \|doi=10.1016/j.humpath.2013.12.021 \|url=}}</ref>

	==See also==		==See also==

Michael at 15:16, 11 September 2017

2017-09-11T15:16:06Z

← Older revision		Revision as of 15:16, 11 September 2017
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			{{ Infobox immunostain
			\| Name = {{PAGENAME}}
			\| Image =
			\| Width =
			\| Caption =
			\| Abbrev =
			\| Synonyms =
			\| Similar =
			\| Clones =
			\| Use = screen to detect TFE3 rearrangements
			\| Subspecial = [[urologic pathology]], [[soft tissue pathology]]
			\| Pattern = nuclear stain
			\| Positive = [[Xp11.2 translocation carcinoma]], [[alveolar soft part sarcoma]]
			\| Negative = normal tissues
			\| Other =
			}}
	'''TFE3''' is an [[immunostain]] used in [[uropathology]] and [[soft tissue pathology]].		'''TFE3''' is an [[immunostain]] used in [[uropathology]] and [[soft tissue pathology]].

Michael: /* Negative */

2017-09-11T15:13:15Z

Negative

← Older revision		Revision as of 15:13, 11 September 2017
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	==Negative==		==Negative==
	*Normal tissue.<ref>URL: [http://www.ihcworld.com/_newsletter/2003/focus_jul_2003.pdf http://www.ihcworld.com/_newsletter/2003/focus_jul_2003.pdf]. Accessed on: September 11, 2017.</ref>		*Normal tissue.<ref>URL: [http://www.ihcworld.com/_newsletter/2003/focus_jul_2003.pdf http://www.ihcworld.com/_newsletter/2003/focus_jul_2003.pdf]. Accessed on: September 11, 2017.</ref>
			**Staining in normal tissue described as "extremely rare" - negative in adrenal gland, breast, colon, gallbaldder, lymph node, liver, prostate and skin.<ref name=pmid12766578>{{Cite journal \| last1 = Argani \| first1 = P. \| last2 = Lal \| first2 = P. \| last3 = Hutchinson \| first3 = B. \| last4 = Lui \| first4 = MY. \| last5 = Reuter \| first5 = VE. \| last6 = Ladanyi \| first6 = M. \| title = Aberrant nuclear immunoreactivity for TFE3 in neoplasms with TFE3 gene fusions: a sensitive and specific immunohistochemical assay. \| journal = Am J Surg Pathol \| volume = 27 \| issue = 6 \| pages = 750-61 \| month = Jun \| year = 2003 \| doi = \| PMID = 12766578 }}</ref>

	==Positive==		==Positive==

Michael: create

2017-09-11T14:31:25Z

create

New page

'''TFE3''' is an [[immunostain]] used in [[uropathology]] and [[soft tissue pathology]].

==Negative==
*Normal tissue.<ref>URL: [http://www.ihcworld.com/_newsletter/2003/focus_jul_2003.pdf http://www.ihcworld.com/_newsletter/2003/focus_jul_2003.pdf]. Accessed on: September 11, 2017.</ref>

==Positive==
*[[Xp11.2 translocation carcinoma]].
*[[Alveolar soft part sarcoma]].

==See also==
*[[Chromosomal translocations]].

==References==
{{Reflist|1}}

[[Category:Immunohistochemistry]]