Surgical margins - Revision history

Michael at 05:38, 9 January 2024

2024-01-09T05:38:12Z

← Older revision		Revision as of 05:38, 9 January 2024
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	\|-		\|-
	\| [[Colorectal carcinoma]]		\| [[Colorectal carcinoma]]
	\| >=1 mm;<ref name=~~pmid12077094~~>{{~~Cite~~ journal \| ~~last1~~ = ~~Petersen \| first1 = VC. \| last2 = Baxter \| first2 = KJ. \| last3 = Love \| first3 = SB. \| last4 = Shepherd \| first4 = NA.~~ \| title = ~~Identification of objective pathological prognostic determinants~~ and ~~models~~ of ~~prognosis~~ in ~~Dukes' B colon~~ cancer~~. \| journal = Gut \| volume = 51 \| issue = 1 \| pages = 65~~-9 \| ~~month = Jul \| year = 2002 \| doi = \| PMC = 1773289 \| PMID = 12077094 \| URL = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1773289/ }}</ref><ref>{{Cite~~ journal ~~\| last1 = Fitzgerald \| first1 = TL. \| last2 = Brinkley \| first2~~ = J~~. \| last3 = Zervos \| first3 = EE. \| title = Pushing the envelope beyond a centimeter in rectal cancer: oncologic implications of close, but negative margins. \| journal = J Am Coll~~ Surg \| volume = ~~213~~ \| issue = 5 \| pages = ~~589-95~~ \| ~~month~~ = ~~Nov~~ \| ~~year~~ = ~~2011~~ \| doi = 10.1016/j.~~jamcollsurg.2011.07.020 \| PMID = 21856181 }}</ref><ref name=pmid2430152>{{Cite journal \| last1 = Quirke \| first1 = P. \| last2 = Durdey \| first2 = P~~. ~~\| last3 = Dixon \| first3 = MF~~. \| last4 = Williams \| first4 = NS. \| title = Local recurrence of rectal adenocarcinoma due to inadequate surgical resection. Histopathological study of lateral tumour spread and surgical excision. \| journal = Lancet \| volume = 2 \| issue = 8514 \| pages = 996-9 \| month = Nov \| year = 1986 \| doi = \| PMID = ~~2430152~~ }}</ref> circumferential margin (esp. in rectal carcinoma) most important<ref name=pmid7915774>{{Cite journal \| last1 = Adam \| first1 = IJ. \| last2 = Mohamdee \| first2 = MO. \| last3 = Martin \| first3 = IG. \| last4 = Scott \| first4 = N. \| last5 = Finan \| first5 = PJ. \| last6 = Johnston \| first6 = D. \| last7 = Dixon \| first7 = MF. \| last8 = Quirke \| first8 = P. \| title = Role of circumferential margin involvement in the local recurrence of rectal cancer. \| journal = Lancet \| volume = 344 \| issue = 8924 \| pages = 707-11 \| month = Sep \| year = 1994 \| doi = \| PMID = 7915774 }}</ref>		\| >1 mm;<ref name=pmid37722286>{{cite journal \|authors=Smith HG, Schlesinger NH, Qvortrup C, Chiranth D, Lundon D, Ben-Yaacov A, Caballero C, Suppan I, Kok JH, Holmberg CJ, Mohan H, Montagna G, Santrac N, Sayyed R, Schrage Y, Sgarbura O, Ceelen W, Lorenzon L, Brandl A \|title=Variations in the definition and perceived importance of positive resection margins in patients with colorectal cancer - an EYSAC international survey \|journal=Eur J Surg Oncol \|volume=49 \|issue=11 \|pages=107072 \|date=November 2023 \|pmid=37722286 \|doi=10.1016/j.ejso.2023.107072 \|url=}}</ref> circumferential margin (esp. in rectal carcinoma) most important<ref name=pmid7915774>{{Cite journal \| last1 = Adam \| first1 = IJ. \| last2 = Mohamdee \| first2 = MO. \| last3 = Martin \| first3 = IG. \| last4 = Scott \| first4 = N. \| last5 = Finan \| first5 = PJ. \| last6 = Johnston \| first6 = D. \| last7 = Dixon \| first7 = MF. \| last8 = Quirke \| first8 = P. \| title = Role of circumferential margin involvement in the local recurrence of rectal cancer. \| journal = Lancet \| volume = 344 \| issue = 8924 \| pages = 707-11 \| month = Sep \| year = 1994 \| doi = \| PMID = 7915774 }}</ref>
	\| 1 cm<ref name=pmid18766404>{{Cite journal \| last1 = Rutkowski \| first1 = A. \| last2 = Bujko \| first2 = K. \| last3 = Nowacki \| first3 = MP. \| last4 = Chmielik \| first4 = E. \| last5 = Nasierowska-Guttmejer \| first5 = A. \| last6 = Wojnar \| first6 = A. \| title = Distal bowel surgical margin shorter than 1 cm after preoperative radiation for rectal cancer: is it safe? \| journal = Ann Surg Oncol \| volume = 15 \| issue = 11 \| pages = 3124-31 \| month = Nov \| year = 2008 \| doi = 10.1245/s10434-008-0125-6 \| PMID = 18766404 }}</ref>		\| 1 cm<ref name=pmid18766404>{{Cite journal \| last1 = Rutkowski \| first1 = A. \| last2 = Bujko \| first2 = K. \| last3 = Nowacki \| first3 = MP. \| last4 = Chmielik \| first4 = E. \| last5 = Nasierowska-Guttmejer \| first5 = A. \| last6 = Wojnar \| first6 = A. \| title = Distal bowel surgical margin shorter than 1 cm after preoperative radiation for rectal cancer: is it safe? \| journal = Ann Surg Oncol \| volume = 15 \| issue = 11 \| pages = 3124-31 \| month = Nov \| year = 2008 \| doi = 10.1245/s10434-008-0125-6 \| PMID = 18766404 }}</ref>
	\| [[Gastrointestinal pathology]]		\| [[Gastrointestinal pathology]]

Michael: /* Positive margin definition */

2022-01-12T21:39:13Z

Positive margin definition

← Older revision		Revision as of 21:39, 12 January 2022
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	Definitionally, there is agreement that "tumour touching the edge of the specimen" is a ''positive margin''.<ref name=pmid26028131>{{cite journal \|authors=Chagpar AB, Killelea BK, Tsangaris TN, Butler M, Stavris K, Li F, Yao X, Bossuyt V, Harigopal M, Lannin DR, Pusztai L, Horowitz NR \|title=A Randomized, Controlled Trial of Cavity Shave Margins in Breast Cancer \|journal=N Engl J Med \|volume=373 \|issue=6 \|pages=503–10 \|date=August 2015 \|pmid=26028131 \|pmc=5584380 \|doi=10.1056/NEJMoa1504473 \|url=}}</ref><ref name=pmid16509840/>		Definitionally, there is agreement that "tumour touching the edge of the specimen" is a ''positive margin''.<ref name=pmid26028131>{{cite journal \|authors=Chagpar AB, Killelea BK, Tsangaris TN, Butler M, Stavris K, Li F, Yao X, Bossuyt V, Harigopal M, Lannin DR, Pusztai L, Horowitz NR \|title=A Randomized, Controlled Trial of Cavity Shave Margins in Breast Cancer \|journal=N Engl J Med \|volume=373 \|issue=6 \|pages=503–10 \|date=August 2015 \|pmid=26028131 \|pmc=5584380 \|doi=10.1056/NEJMoa1504473 \|url=}}</ref><ref name=pmid16509840/>

	It may be useful to differentiate ''pathologic margin [status]'' (tumour touching inked margin) and ''oncologic margin [status]'' (tumour sufficiently clear of margin to not affect the prognosis). Oncologists, surgeons and patients really only care about ''oncologic margin [status]'' for relatively obvious reasons.		It may be useful to differentiate ''pathologic margin [status]'' (tumour touching inked margin) and ''oncologic margin [status]'' (tumour sufficiently clear of margin to not significantly affect the prognosis). Oncologists, surgeons and patients really only care about ''oncologic margin [status]'' for relatively obvious reasons.

	Perhaps confusing is that: ''a [pathologically] clear margin'' may be defined as being ''[oncologically] a positive margin'', e.g. tumour ''not'' touching the ink of an inked margin - but less than 1 mm from the ink - may be a "positive margin".<ref name=pmid16509840>{{cite journal \|authors=Scopa CD, Aroukatos P, Tsamandas AC, Aletra C \|title=Evaluation of margin status in lumpectomy specimens and residual breast carcinoma \|journal=Breast J \|volume=12 \|issue=2 \|pages=150–3 \|date=2006 \|pmid=16509840 \|doi=10.1111/j.1075-122X.2006.00223.x \|url=}}</ref>		Perhaps confusing is that: ''a [pathologically] clear margin'' may be defined as being ''[oncologically] a positive margin'', e.g. tumour ''not'' touching the ink of an inked margin - but less than 1 mm from the ink - may be a "positive margin".<ref name=pmid16509840>{{cite journal \|authors=Scopa CD, Aroukatos P, Tsamandas AC, Aletra C \|title=Evaluation of margin status in lumpectomy specimens and residual breast carcinoma \|journal=Breast J \|volume=12 \|issue=2 \|pages=150–3 \|date=2006 \|pmid=16509840 \|doi=10.1111/j.1075-122X.2006.00223.x \|url=}}</ref>

Michael: /* Positive margin definition */

2022-01-12T21:38:36Z

Positive margin definition

← Older revision		Revision as of 21:38, 12 January 2022
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	Definitionally, there is agreement that "tumour touching the edge of the specimen" is a ''positive margin''.<ref name=pmid26028131>{{cite journal \|authors=Chagpar AB, Killelea BK, Tsangaris TN, Butler M, Stavris K, Li F, Yao X, Bossuyt V, Harigopal M, Lannin DR, Pusztai L, Horowitz NR \|title=A Randomized, Controlled Trial of Cavity Shave Margins in Breast Cancer \|journal=N Engl J Med \|volume=373 \|issue=6 \|pages=503–10 \|date=August 2015 \|pmid=26028131 \|pmc=5584380 \|doi=10.1056/NEJMoa1504473 \|url=}}</ref><ref name=pmid16509840/>		Definitionally, there is agreement that "tumour touching the edge of the specimen" is a ''positive margin''.<ref name=pmid26028131>{{cite journal \|authors=Chagpar AB, Killelea BK, Tsangaris TN, Butler M, Stavris K, Li F, Yao X, Bossuyt V, Harigopal M, Lannin DR, Pusztai L, Horowitz NR \|title=A Randomized, Controlled Trial of Cavity Shave Margins in Breast Cancer \|journal=N Engl J Med \|volume=373 \|issue=6 \|pages=503–10 \|date=August 2015 \|pmid=26028131 \|pmc=5584380 \|doi=10.1056/NEJMoa1504473 \|url=}}</ref><ref name=pmid16509840/>

	It may be useful to differentiate ''pathologic margin [status]'' (tumour touching ~~ink~~) and ''oncologic margin [status]'' (tumour sufficiently clear of margin to not affect the prognosis). Oncologists, surgeons and patients really only care about ''oncologic margin [status]'' for relatively obvious reasons.		It may be useful to differentiate ''pathologic margin [status]'' (tumour touching inked margin) and ''oncologic margin [status]'' (tumour sufficiently clear of margin to not affect the prognosis). Oncologists, surgeons and patients really only care about ''oncologic margin [status]'' for relatively obvious reasons.

	Perhaps confusing is that: ''a [pathologically] clear margin'' may be defined as being ''[oncologically] a positive margin'', e.g. tumour ''not'' touching the ink of an inked margin - but less than 1 mm from the ink - may be a "positive margin".<ref name=pmid16509840>{{cite journal \|authors=Scopa CD, Aroukatos P, Tsamandas AC, Aletra C \|title=Evaluation of margin status in lumpectomy specimens and residual breast carcinoma \|journal=Breast J \|volume=12 \|issue=2 \|pages=150–3 \|date=2006 \|pmid=16509840 \|doi=10.1111/j.1075-122X.2006.00223.x \|url=}}</ref>		Perhaps confusing is that: ''a [pathologically] clear margin'' may be defined as being ''[oncologically] a positive margin'', e.g. tumour ''not'' touching the ink of an inked margin - but less than 1 mm from the ink - may be a "positive margin".<ref name=pmid16509840>{{cite journal \|authors=Scopa CD, Aroukatos P, Tsamandas AC, Aletra C \|title=Evaluation of margin status in lumpectomy specimens and residual breast carcinoma \|journal=Breast J \|volume=12 \|issue=2 \|pages=150–3 \|date=2006 \|pmid=16509840 \|doi=10.1111/j.1075-122X.2006.00223.x \|url=}}</ref>

Michael: /* Positive margin definition */

2022-01-12T21:37:46Z

Positive margin definition

← Older revision		Revision as of 21:37, 12 January 2022
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	Unfortunately, there is no universal definition for ''positive margin''.		Unfortunately, there is no universal definition for ''positive margin''.

	Definitionally, there is agreement that "tumour touching the edge of the specimen" is a ''positive margin''.<ref name=pmid26028131>{{cite journal \|authors=Chagpar AB, Killelea BK, Tsangaris TN, Butler M, Stavris K, Li F, Yao X, Bossuyt V, Harigopal M, Lannin DR, Pusztai L, Horowitz NR \|title=A Randomized, Controlled Trial of Cavity Shave Margins in Breast Cancer \|journal=N Engl J Med \|volume=373 \|issue=6 \|pages=503–10 \|date=August 2015 \|pmid=26028131 \|pmc=5584380 \|doi=10.1056/NEJMoa1504473 \|url=}}</ref>		Definitionally, there is agreement that "tumour touching the edge of the specimen" is a ''positive margin''.<ref name=pmid26028131>{{cite journal \|authors=Chagpar AB, Killelea BK, Tsangaris TN, Butler M, Stavris K, Li F, Yao X, Bossuyt V, Harigopal M, Lannin DR, Pusztai L, Horowitz NR \|title=A Randomized, Controlled Trial of Cavity Shave Margins in Breast Cancer \|journal=N Engl J Med \|volume=373 \|issue=6 \|pages=503–10 \|date=August 2015 \|pmid=26028131 \|pmc=5584380 \|doi=10.1056/NEJMoa1504473 \|url=}}</ref><ref name=pmid16509840/>

	It may be useful to differentiate ''pathologic margin [status]'' (tumour touching ink) and ''oncologic margin [status]'' (tumour sufficiently clear of margin to not affect the prognosis). Oncologists, surgeons and patients really only care about ''oncologic margin [status]'' for relatively obvious reasons.		It may be useful to differentiate ''pathologic margin [status]'' (tumour touching ink) and ''oncologic margin [status]'' (tumour sufficiently clear of margin to not affect the prognosis). Oncologists, surgeons and patients really only care about ''oncologic margin [status]'' for relatively obvious reasons.

Michael: /* Positive margin definition */

2022-01-12T21:33:54Z

Positive margin definition

← Older revision		Revision as of 21:33, 12 January 2022
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	Definitionally, there is agreement that "tumour touching the edge of the specimen" is a ''positive margin''.<ref name=pmid26028131>{{cite journal \|authors=Chagpar AB, Killelea BK, Tsangaris TN, Butler M, Stavris K, Li F, Yao X, Bossuyt V, Harigopal M, Lannin DR, Pusztai L, Horowitz NR \|title=A Randomized, Controlled Trial of Cavity Shave Margins in Breast Cancer \|journal=N Engl J Med \|volume=373 \|issue=6 \|pages=503–10 \|date=August 2015 \|pmid=26028131 \|pmc=5584380 \|doi=10.1056/NEJMoa1504473 \|url=}}</ref>		Definitionally, there is agreement that "tumour touching the edge of the specimen" is a ''positive margin''.<ref name=pmid26028131>{{cite journal \|authors=Chagpar AB, Killelea BK, Tsangaris TN, Butler M, Stavris K, Li F, Yao X, Bossuyt V, Harigopal M, Lannin DR, Pusztai L, Horowitz NR \|title=A Randomized, Controlled Trial of Cavity Shave Margins in Breast Cancer \|journal=N Engl J Med \|volume=373 \|issue=6 \|pages=503–10 \|date=August 2015 \|pmid=26028131 \|pmc=5584380 \|doi=10.1056/NEJMoa1504473 \|url=}}</ref>

	It may be useful to differentiate ''pathologic margin'' (tumour touching ink) and ''oncologic margin'' (tumour sufficiently clear of margin to not affect the prognosis). Oncologists, surgeons and patients really only care about ''oncologic margin'' for relatively obvious reasons.		It may be useful to differentiate ''pathologic margin [status]'' (tumour touching ink) and ''oncologic margin [status]'' (tumour sufficiently clear of margin to not affect the prognosis). Oncologists, surgeons and patients really only care about ''oncologic margin [status]'' for relatively obvious reasons.

	Perhaps confusing is that: ''a [pathologically] clear margin'' may be defined as being ''[oncologically] a positive margin'', e.g. tumour ''not'' touching the ink of an inked margin - but less than 1 mm from the ink - may be a "positive margin".<ref name=pmid16509840>{{cite journal \|authors=Scopa CD, Aroukatos P, Tsamandas AC, Aletra C \|title=Evaluation of margin status in lumpectomy specimens and residual breast carcinoma \|journal=Breast J \|volume=12 \|issue=2 \|pages=150–3 \|date=2006 \|pmid=16509840 \|doi=10.1111/j.1075-122X.2006.00223.x \|url=}}</ref>		Perhaps confusing is that: ''a [pathologically] clear margin'' may be defined as being ''[oncologically] a positive margin'', e.g. tumour ''not'' touching the ink of an inked margin - but less than 1 mm from the ink - may be a "positive margin".<ref name=pmid16509840>{{cite journal \|authors=Scopa CD, Aroukatos P, Tsamandas AC, Aletra C \|title=Evaluation of margin status in lumpectomy specimens and residual breast carcinoma \|journal=Breast J \|volume=12 \|issue=2 \|pages=150–3 \|date=2006 \|pmid=16509840 \|doi=10.1111/j.1075-122X.2006.00223.x \|url=}}</ref>

Michael: /* Positive margin definition */

2022-01-12T21:32:14Z

Positive margin definition

← Older revision		Revision as of 21:32, 12 January 2022
Line 26:		Line 26:
	It may be useful to differentiate ''pathologic margin'' (tumour touching ink) and ''oncologic margin'' (tumour sufficiently clear of margin to not affect the prognosis). Oncologists, surgeons and patients really only care about ''oncologic margin'' for relatively obvious reasons.		It may be useful to differentiate ''pathologic margin'' (tumour touching ink) and ''oncologic margin'' (tumour sufficiently clear of margin to not affect the prognosis). Oncologists, surgeons and patients really only care about ''oncologic margin'' for relatively obvious reasons.

	Perhaps confusing is that: ''a [pathologically] clear margin'' may be defined as being ''[oncologically] a positive margin'', e.g. tumour ~~clear~~ of ~~the~~ inked margin but less than 1 mm from the ink may be a "positive margin".<ref name=pmid16509840>{{cite journal \|authors=Scopa CD, Aroukatos P, Tsamandas AC, Aletra C \|title=Evaluation of margin status in lumpectomy specimens and residual breast carcinoma \|journal=Breast J \|volume=12 \|issue=2 \|pages=150–3 \|date=2006 \|pmid=16509840 \|doi=10.1111/j.1075-122X.2006.00223.x \|url=}}</ref>		Perhaps confusing is that: ''a [pathologically] clear margin'' may be defined as being ''[oncologically] a positive margin'', e.g. tumour ''not'' touching the ink of an inked margin - but less than 1 mm from the ink - may be a "positive margin".<ref name=pmid16509840>{{cite journal \|authors=Scopa CD, Aroukatos P, Tsamandas AC, Aletra C \|title=Evaluation of margin status in lumpectomy specimens and residual breast carcinoma \|journal=Breast J \|volume=12 \|issue=2 \|pages=150–3 \|date=2006 \|pmid=16509840 \|doi=10.1111/j.1075-122X.2006.00223.x \|url=}}</ref>

	==Adequate margin==		==Adequate margin==

Michael: /* Positive margin definition */

2022-01-12T21:31:21Z

Positive margin definition

← Older revision		Revision as of 21:31, 12 January 2022
Line 26:		Line 26:
	It may be useful to differentiate ''pathologic margin'' (tumour touching ink) and ''oncologic margin'' (tumour sufficiently clear of margin to not affect the prognosis). Oncologists, surgeons and patients really only care about ''oncologic margin'' for relatively obvious reasons.		It may be useful to differentiate ''pathologic margin'' (tumour touching ink) and ''oncologic margin'' (tumour sufficiently clear of margin to not affect the prognosis). Oncologists, surgeons and patients really only care about ''oncologic margin'' for relatively obvious reasons.

	Perhaps confusing is that: ''a [pathologically] clear margin'' may be defined as being ''[oncologically] a positive margin'', i.e. tumour clear of the inked margin but less than 1 mm from the ink may be a "positive margin".<ref name=pmid16509840>{{cite journal \|authors=Scopa CD, Aroukatos P, Tsamandas AC, Aletra C \|title=Evaluation of margin status in lumpectomy specimens and residual breast carcinoma \|journal=Breast J \|volume=12 \|issue=2 \|pages=150–3 \|date=2006 \|pmid=16509840 \|doi=10.1111/j.1075-122X.2006.00223.x \|url=}}</ref>		Perhaps confusing is that: ''a [pathologically] clear margin'' may be defined as being ''[oncologically] a positive margin'', e.g. tumour clear of the inked margin but less than 1 mm from the ink may be a "positive margin".<ref name=pmid16509840>{{cite journal \|authors=Scopa CD, Aroukatos P, Tsamandas AC, Aletra C \|title=Evaluation of margin status in lumpectomy specimens and residual breast carcinoma \|journal=Breast J \|volume=12 \|issue=2 \|pages=150–3 \|date=2006 \|pmid=16509840 \|doi=10.1111/j.1075-122X.2006.00223.x \|url=}}</ref>

	==Adequate margin==		==Adequate margin==

Michael: /* Positive margin definition */

2022-01-12T21:30:54Z

Positive margin definition

← Older revision		Revision as of 21:30, 12 January 2022
Line 26:		Line 26:
	It may be useful to differentiate ''pathologic margin'' (tumour touching ink) and ''oncologic margin'' (tumour sufficiently clear of margin to not affect the prognosis). Oncologists, surgeons and patients really only care about ''oncologic margin'' for relatively obvious reasons.		It may be useful to differentiate ''pathologic margin'' (tumour touching ink) and ''oncologic margin'' (tumour sufficiently clear of margin to not affect the prognosis). Oncologists, surgeons and patients really only care about ''oncologic margin'' for relatively obvious reasons.

	Perhaps confusing is that: ''a [pathologically] clear margin'' may be defined as being a ''positive margin'', i.e. tumour clear of the inked margin but less than 1 mm from the ink may be a "positive margin".<ref name=pmid16509840>{{cite journal \|authors=Scopa CD, Aroukatos P, Tsamandas AC, Aletra C \|title=Evaluation of margin status in lumpectomy specimens and residual breast carcinoma \|journal=Breast J \|volume=12 \|issue=2 \|pages=150–3 \|date=2006 \|pmid=16509840 \|doi=10.1111/j.1075-122X.2006.00223.x \|url=}}</ref>		Perhaps confusing is that: ''a [pathologically] clear margin'' may be defined as being ''[oncologically] a positive margin'', i.e. tumour clear of the inked margin but less than 1 mm from the ink may be a "positive margin".<ref name=pmid16509840>{{cite journal \|authors=Scopa CD, Aroukatos P, Tsamandas AC, Aletra C \|title=Evaluation of margin status in lumpectomy specimens and residual breast carcinoma \|journal=Breast J \|volume=12 \|issue=2 \|pages=150–3 \|date=2006 \|pmid=16509840 \|doi=10.1111/j.1075-122X.2006.00223.x \|url=}}</ref>

	==Adequate margin==		==Adequate margin==

Michael: /* Positive margin definition */

2022-01-12T21:29:41Z

Positive margin definition

← Older revision		Revision as of 21:29, 12 January 2022
Line 26:		Line 26:
	It may be useful to differentiate ''pathologic margin'' (tumour touching ink) and ''oncologic margin'' (tumour sufficiently clear of margin to not affect the prognosis). Oncologists, surgeons and patients really only care about ''oncologic margin'' for relatively obvious reasons.		It may be useful to differentiate ''pathologic margin'' (tumour touching ink) and ''oncologic margin'' (tumour sufficiently clear of margin to not affect the prognosis). Oncologists, surgeons and patients really only care about ''oncologic margin'' for relatively obvious reasons.

	Perhaps confusing is that: ''[pathologically] clear margin'' may be defined as being a ''positive margin'', i.e. tumour clear of the inked margin but less than 1 mm from the ink may be a "positive margin".<ref name=pmid16509840>{{cite journal \|authors=Scopa CD, Aroukatos P, Tsamandas AC, Aletra C \|title=Evaluation of margin status in lumpectomy specimens and residual breast carcinoma \|journal=Breast J \|volume=12 \|issue=2 \|pages=150–3 \|date=2006 \|pmid=16509840 \|doi=10.1111/j.1075-122X.2006.00223.x \|url=}}</ref>		Perhaps confusing is that: ''a [pathologically] clear margin'' may be defined as being a ''positive margin'', i.e. tumour clear of the inked margin but less than 1 mm from the ink may be a "positive margin".<ref name=pmid16509840>{{cite journal \|authors=Scopa CD, Aroukatos P, Tsamandas AC, Aletra C \|title=Evaluation of margin status in lumpectomy specimens and residual breast carcinoma \|journal=Breast J \|volume=12 \|issue=2 \|pages=150–3 \|date=2006 \|pmid=16509840 \|doi=10.1111/j.1075-122X.2006.00223.x \|url=}}</ref>

	==Adequate margin==		==Adequate margin==

Michael: /* Positive margin definition */

2022-01-12T21:29:12Z

Positive margin definition

← Older revision		Revision as of 21:29, 12 January 2022
Line 26:		Line 26:
	It may be useful to differentiate ''pathologic margin'' (tumour touching ink) and ''oncologic margin'' (tumour sufficiently clear of margin to not affect the prognosis). Oncologists, surgeons and patients really only care about ''oncologic margin'' for relatively obvious reasons.		It may be useful to differentiate ''pathologic margin'' (tumour touching ink) and ''oncologic margin'' (tumour sufficiently clear of margin to not affect the prognosis). Oncologists, surgeons and patients really only care about ''oncologic margin'' for relatively obvious reasons.

	Perhaps confusing is that: ''[pathologically] clear ~~margins~~'' may be defined as being a ''positive margin'', i.e. tumour less than 1 mm may be a "positive margin".<ref name=pmid16509840>{{cite journal \|authors=Scopa CD, Aroukatos P, Tsamandas AC, Aletra C \|title=Evaluation of margin status in lumpectomy specimens and residual breast carcinoma \|journal=Breast J \|volume=12 \|issue=2 \|pages=150–3 \|date=2006 \|pmid=16509840 \|doi=10.1111/j.1075-122X.2006.00223.x \|url=}}</ref>		Perhaps confusing is that: ''[pathologically] clear margin'' may be defined as being a ''positive margin'', i.e. tumour clear of the inked margin but less than 1 mm from the ink may be a "positive margin".<ref name=pmid16509840>{{cite journal \|authors=Scopa CD, Aroukatos P, Tsamandas AC, Aletra C \|title=Evaluation of margin status in lumpectomy specimens and residual breast carcinoma \|journal=Breast J \|volume=12 \|issue=2 \|pages=150–3 \|date=2006 \|pmid=16509840 \|doi=10.1111/j.1075-122X.2006.00223.x \|url=}}</ref>

	==Adequate margin==		==Adequate margin==