Spindle cell lipoma - Revision history

Michael: tweka

2017-12-30T06:20:36Z

tweka

← Older revision		Revision as of 06:20, 30 December 2017
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	\| LMDDx = [[neurofibroma]], spindle cell [[liposarcoma]], [[pleomorphic lipoma]]		\| LMDDx = [[neurofibroma]], spindle cell [[liposarcoma]], [[pleomorphic lipoma]]
	\| Stains =		\| Stains =
	\| IHC =		\| IHC = CD34 +ve, MDM2 -ve
	\| EM =		\| EM =
	\| Molecular =		\| Molecular =

Michael: /* Images */

2017-12-30T06:18:38Z

Images

← Older revision		Revision as of 06:18, 30 December 2017
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	===Images===		===Images===
	<gallery>		<gallery>
	Image: Spindle cell lipoma -- low mag.jpg \| ~~SSL~~ - low mag. (WC/Nephron)		Image: Spindle cell lipoma -- low mag.jpg \| SCL - low mag. (WC/Nephron)
	Image: Spindle cell lipoma -- intermed mag.jpg \| ~~SSL~~ - intermed. mag. (WC/Nephron)		Image: Spindle cell lipoma -- intermed mag.jpg \| SCL - intermed. mag. (WC/Nephron)
	Image: Spindle cell lipoma -- high mag.jpg \| ~~SSL~~ - high mag. (WC/Nephron)		Image: Spindle cell lipoma -- high mag.jpg \| SCL - high mag. (WC/Nephron)
			</gallery>
			<gallery>
			Image: Spindle Cell Lipoma (2275051876).jpg \| SCL (WC/Uthman)
	</gallery>		</gallery>


	====www====		====www====
	*[http://www.webpathology.com/image.asp?n=3&Case=434 Spindle cell lipoma (webpathology.com)].		*[http://www.webpathology.com/image.asp?n=3&Case=434 Spindle cell lipoma (webpathology.com)].

Michael: /* Microscopic */

2017-12-30T06:17:21Z

Microscopic

← Older revision		Revision as of 06:17, 30 December 2017
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	*Spindle cell [[liposarcoma]] - extremely rare.<ref name=pmid8067512>{{Cite journal \| last1 = Dei Tos \| first1 = AP. \| last2 = Mentzel \| first2 = T. \| last3 = Newman \| first3 = PL. \| last4 = Fletcher \| first4 = CD. \| title = Spindle cell liposarcoma, a hitherto unrecognized variant of liposarcoma. Analysis of six cases. \| journal = Am J Surg Pathol \| volume = 18 \| issue = 9 \| pages = 913-21 \| month = Sep \| year = 1994 \| doi = \| PMID = 8067512 }}</ref>		*Spindle cell [[liposarcoma]] - extremely rare.<ref name=pmid8067512>{{Cite journal \| last1 = Dei Tos \| first1 = AP. \| last2 = Mentzel \| first2 = T. \| last3 = Newman \| first3 = PL. \| last4 = Fletcher \| first4 = CD. \| title = Spindle cell liposarcoma, a hitherto unrecognized variant of liposarcoma. Analysis of six cases. \| journal = Am J Surg Pathol \| volume = 18 \| issue = 9 \| pages = 913-21 \| month = Sep \| year = 1994 \| doi = \| PMID = 8067512 }}</ref>

	===Image===		===Images===
	www:		<gallery>
			Image: Spindle cell lipoma -- low mag.jpg \| SSL - low mag. (WC/Nephron)
			Image: Spindle cell lipoma -- intermed mag.jpg \| SSL - intermed. mag. (WC/Nephron)
			Image: Spindle cell lipoma -- high mag.jpg \| SSL - high mag. (WC/Nephron)
			</gallery>


			====www====
	*[http://www.webpathology.com/image.asp?n=3&Case=434 Spindle cell lipoma (webpathology.com)].		*[http://www.webpathology.com/image.asp?n=3&Case=434 Spindle cell lipoma (webpathology.com)].

Michael at 06:15, 30 December 2017

2017-12-30T06:15:56Z

← Older revision		Revision as of 06:15, 30 December 2017
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			{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image = Spindle_cell_lipoma_--_high_mag.jpg
			\| Width =
			\| Caption = [[Micrograph]] showing a spindle cell lipoma. [[H&E stain]].
			\| Synonyms =
			\| Micro = aligned bland spindled cells adjacent to fat, rope-like collagen bundles (key feature), +/-[[myxoid]] component, +/-[[staghorn vessels\|staghorn-like vessels]]
			\| Subtypes =
			\| LMDDx = [[neurofibroma]], spindle cell [[liposarcoma]], [[pleomorphic lipoma]]
			\| Stains =
			\| IHC =
			\| EM =
			\| Molecular =
			\| IF =
			\| Gross =
			\| Grossing =
			\| Staging =
			\| Site =
			\| Assdx =
			\| Syndromes =
			\| Clinicalhx =
			\| Signs =
			\| Symptoms =
			\| Prevalence = uncommon
			\| Bloodwork =
			\| Rads =
			\| Endoscopy =
			\| Prognosis = benign
			\| Other =
			\| ClinDDx =
			\| Tx =
			}}
	'''Spindle cell lipoma''' is a rare benign [[adipocytic tumours\|adipocytic tumour]].		'''Spindle cell lipoma''' is a rare benign [[adipocytic tumours\|adipocytic tumour]].

Michael: split out

2016-05-01T22:53:32Z

split out

← Older revision		Revision as of 22:53, 1 May 2016
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	~~#redirect~~ [[~~Adipocytic_tumours#Spindle_cell_lipoma~~]]		'''Spindle cell lipoma''' is a rare benign [[adipocytic tumours\|adipocytic tumour]].

			==General==
			*Rare.
			*Predominantly men.<ref name=pmid15371618/>

			Note:
			*Spindle cell lipoma may immunohistochemically and histomorphologically overlap with ''mammary-type myofibroblastoma''<ref name=pmid11474286>{{Cite journal \| last1 = McMenamin \| first1 = ME. \| last2 = Fletcher \| first2 = CD. \| title = Mammary-type myofibroblastoma of soft tissue: a tumor closely related to spindle cell lipoma. \| journal = Am J Surg Pathol \| volume = 25 \| issue = 8 \| pages = 1022-9 \| month = Aug \| year = 2001 \| doi = \| PMID = 11474286 }}</ref> - see: ''[[mammary myofibroblastoma]]''.

			==Microscopic==
			Features:<ref name=pmid15371618>{{Cite journal \| last1 = Murphey \| first1 = MD. \| last2 = Carroll \| first2 = JF. \| last3 = Flemming \| first3 = DJ. \| last4 = Pope \| first4 = TL. \| last5 = Gannon \| first5 = FH. \| last6 = Kransdorf \| first6 = MJ. \| title = From the archives of the AFIP: benign musculoskeletal lipomatous lesions. \| journal = Radiographics \| volume = 24 \| issue = 5 \| pages = 1433-66 \| month = \| year = \| doi = 10.1148/rg.245045120 \| PMID = 15371618 }}</ref>
			*Aligned bland spindled cells adjacent to fat.
			*Rope-like collagen bundles - '''key feature'''.
			**May be described as "shreaded wheat".
			*+/-[[Myxoid]] component.
			*+/-[[staghorn vessels\|Staghorn-like vessels]].

			Notes:
			*May overlap with ''[[pleomorphic lipoma]]''.<ref name=spc_stanford>URL: [http://surgpathcriteria.stanford.edu/softfat/spindle_cell_lipoma/ http://surgpathcriteria.stanford.edu/softfat/spindle_cell_lipoma/]. Accessed on: 4 December 2010.</ref>

			DDx:
			*[[Neurofibroma]].
			*Spindle cell [[liposarcoma]] - extremely rare.<ref name=pmid8067512>{{Cite journal \| last1 = Dei Tos \| first1 = AP. \| last2 = Mentzel \| first2 = T. \| last3 = Newman \| first3 = PL. \| last4 = Fletcher \| first4 = CD. \| title = Spindle cell liposarcoma, a hitherto unrecognized variant of liposarcoma. Analysis of six cases. \| journal = Am J Surg Pathol \| volume = 18 \| issue = 9 \| pages = 913-21 \| month = Sep \| year = 1994 \| doi = \| PMID = 8067512 }}</ref>

			===Image===
			www:
			*[http://www.webpathology.com/image.asp?n=3&Case=434 Spindle cell lipoma (webpathology.com)].

			==IHC==
			*CD34 +ve.<ref name=pmid20559119>{{Cite journal \| last1 = Wood \| first1 = L. \| last2 = Fountaine \| first2 = TJ. \| last3 = Rosamilia \| first3 = L. \| last4 = Helm \| first4 = KF. \| last5 = Clarke \| first5 = LE. \| title = Cutaneous CD34+ spindle cell neoplasms: Histopathologic features distinguish spindle cell lipoma, solitary fibrous tumor, and dermatofibrosarcoma protuberans. \| journal = Am J Dermatopathol \| volume = 32 \| issue = 8 \| pages = 764-8 \| month = Dec \| year = 2010 \| doi = 10.1097/DAD.0b013e3181d0c587 \| PMID = 20559119 }}</ref>
			*Desmin +ve.
			*S100 -ve. (???)

			Lipoma versus liposarcoma:
			*MDM2 -ve.<ref name=pmid23529275>{{Cite journal \| last1 = Alshenawy \| first1 = H. \| title = Can HMGI-C be used as an aid with MDM2 and CDK4 to differentiate liposarcoma subtypes from their mimics? \| journal = J Cancer Res Clin Oncol \| volume = 139 \| issue = 6 \| pages = 1073-81 \| month = Jun \| year = 2013 \| doi = 10.1007/s00432-013-1420-6 \| PMID = 23529275 }}</ref>
			*p16 -ve.<ref name=pmid24659226>{{Cite journal \| last1 = Creytens \| first1 = D. \| last2 = van Gorp \| first2 = J. \| last3 = Savola \| first3 = S. \| last4 = Ferdinande \| first4 = L. \| last5 = Mentzel \| first5 = T. \| last6 = Libbrecht \| first6 = L. \| title = Atypical spindle cell lipoma: a clinicopathologic, immunohistochemical, and molecular study emphasizing its relationship to classical spindle cell lipoma. \| journal = Virchows Arch \| volume = 465 \| issue = 1 \| pages = 97-108 \| month = Jul \| year = 2014 \| doi = 10.1007/s00428-014-1568-8 \| PMID = 24659226 }}</ref>

			==Molecular==
			*Retinoblastoma (Rb) deletions.<ref name=pmid24659226>{{Cite journal \| last1 = Creytens \| first1 = D. \| last2 = van Gorp \| first2 = J. \| last3 = Savola \| first3 = S. \| last4 = Ferdinande \| first4 = L. \| last5 = Mentzel \| first5 = T. \| last6 = Libbrecht \| first6 = L. \| title = Atypical spindle cell lipoma: a clinicopathologic, immunohistochemical, and molecular study emphasizing its relationship to classical spindle cell lipoma. \| journal = Virchows Arch \| volume = 465 \| issue = 1 \| pages = 97-108 \| month = Jul \| year = 2014 \| doi = 10.1007/s00428-014-1568-8 \| PMID = 24659226 }}</ref>
			*CDK4 no amplication ([[FISH]]).<ref name=pmid24659226/>

			==See also==
			*[[Mammary myofibroblastoma]].
			*[[Pleomorphic lipoma]].

			==References==
			{{Reflist\|2}}

	[[Category:Diagnosis]]		[[Category:Diagnosis]]
			[[Category:Adipocytic tumours]]

Michael: +cat.

2011-10-20T04:49:35Z

+cat.

← Older revision		Revision as of 04:49, 20 October 2011
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	#redirect [[Adipocytic_tumours#Spindle_cell_lipoma]]		#redirect [[Adipocytic_tumours#Spindle_cell_lipoma]]

			[[Category:Diagnosis]]

Michael: redirect

2011-08-17T18:07:27Z

redirect

New page

#redirect [[Adipocytic_tumours#Spindle_cell_lipoma]]