Rheumatoid arthritis - Revision history

Michael at 15:53, 10 April 2023

2023-04-10T15:53:31Z

← Older revision		Revision as of 15:53, 10 April 2023
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	Comment:		Comment:
	The history rheumatoid arthritis and deformities is noted.		The history of rheumatoid arthritis and deformities is noted.
	</pre>		</pre>

Michael: fix

2023-04-10T15:52:35Z

fix

← Older revision		Revision as of 15:52, 10 April 2023
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	<pre>		<pre>
	Right Hand - Metacarpal Heads of Index Finger, Middle Finger and Ring Finger, Excision:		Right Hand - Metacarpal Heads of Index Finger, Middle Finger and Ring Finger, Excision:
	- Benign bone and cartilage focally associated with fibrous tissue.		- Benign bone and cartilage focally associated with fibrous tissue and erosions.
	- Fatty marrow space.		- Fatty marrow space.
	- NEGATIVE for ~~insignificant~~ inflammation.		- NEGATIVE for significant inflammation.
	- NEGATIVE for malignancy.		- NEGATIVE for malignancy.

Michael at 15:47, 10 April 2023

2023-04-10T15:47:58Z

← Older revision		Revision as of 15:47, 10 April 2023
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	<pre>		<pre>
	Right Hand - Metacarpal Heads of Index Finger, Middle Finger and Ring Finger, Excision:		Right Hand - Metacarpal Heads of Index Finger, Middle Finger and Ring Finger, Excision:
	- Benign bone ~~with~~ cartilage focally associated with fibrous tissue.		- Benign bone and cartilage focally associated with fibrous tissue.
	- Fatty marrow space.		- Fatty marrow space.
	- NEGATIVE for insignificant inflammation.		- NEGATIVE for insignificant inflammation.

Michael: +another so

2023-04-10T15:46:43Z

+another so

← Older revision		Revision as of 15:46, 10 April 2023
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	====Hand====		====Hand====
			<pre>
			Right Hand - Metacarpal Heads of Index Finger, Middle Finger and Ring Finger, Excision:
			- Benign bone with cartilage focally associated with fibrous tissue.
			- Fatty marrow space.
			- NEGATIVE for insignificant inflammation.
			- NEGATIVE for malignancy.

			Comment:
			The history rheumatoid arthritis and deformities is noted.
			</pre>

	<pre>		<pre>
	SYNOVIUM, LEFT HAND, EXCISION:		SYNOVIUM, LEFT HAND, EXCISION:

Michael: /* Rheumatoid nodule */ split out

2014-11-09T03:49:21Z

Rheumatoid nodule: split out

← Older revision		Revision as of 03:49, 9 November 2014
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	==Rheumatoid nodule==		==Rheumatoid nodule==
	{{ ~~Infobox external links~~		{{Main\|Rheumatoid nodule}}
	\| ~~Name =~~ Rheumatoid nodule		{{Main\|Rheumatoid lung nodule}}
	~~\| EHVSC = 10182~~
	~~\| pathprotocols =~~
	~~\| wikipedia =~~
	~~\| pathoutlines =~~
	}}
	*Abbreviated ''RN''.
	~~===General===~~
	*Seen in [[rheumatoid arthritis]] - usually only in seropositive cases, i.e. ''rheumatoid factor'' (RF) positive.<ref name=Ref_DCHH299>{{~~Ref DCHH~~\|~~299}}</ref>~~
	**Exceptions are reported.<ref name=pmid6364806>{{Cite journal \| last1 = Kaye \| first1 = BR. \| last2 = Kaye \| first2 = RL. \| last3 = Bobrove \| first3 = A. \| title = Rheumatoid nodules. Review of the spectrum of associated conditions and proposal of a new classification, with a report of four seronegative cases. \| journal = Am J Med \| volume = 76 \| issue = 2 \| pages = 279-92 \| month = Feb \| year = 1984 \| doi = \| PMID = 6364806 }}</ref>

	~~===Gross===~~
	*Usually on the extensor aspect of the extremities, e.g. dorsal aspect of elbow.<ref name=Ref_Derm53>{{Ref Derm\|53}}</ref>
	*Typically close to a joint.{{fact}}

	~~===Microscopic===~~
	~~Features:<ref name=Ref_DCHH299>{{Ref DCHH\|299}}</ref><ref name=Ref_Derm52>{{Ref Derm\|52}}</ref>~~
	*Necrotic collagen bundles with fibrin surrounded by:
	**Palisading [[granuloma]].
	*+/-Eosinophils.

	~~Notes:~~
	*Histomorphologically very similar to ''[[Granuloma annulare]]''.

	~~DDx:~~
	*[[Granuloma annulare]] - has mucin in the core of the granuloma.<ref name=Ref_Derm52>{{Ref Derm\|52}}</ref>
	*[[Necrobiosis lipoidica]].

	~~===Images===~~
	~~www:~~
	*[http://granuloma.homestead.com/rheumatoid_nod_S89-2617-1.jpg Rheumatoid nodule ~~(granuloma.homestead.com)].<ref name=ghc>URL: [http://granuloma.homestead.com/palisading.html http://granuloma.homestead.com/palisading.html]. Accessed on: 1 November 2010.</ref>~~
	*[http://granuloma.homestead.com/rheumatoid_nod_S89-2617-5.jpg Rheumatoid nodule (granuloma.homestead.com)].<ref name=ghc>URL: [http://granuloma.homestead.com/palisading.html http://granuloma.homestead.com/palisading.html]. Accessed on: 1 November 2010.</ref>
	*[http://library.med.utah.edu/WebPath/jpeg3/BONE045.jpg Rheumatoid nodule (utah.edu)].<ref>URL: [http://www.pathguy.com/lectures/joints.htm http://www.pathguy.com/lectures/joints.htm]. Accessed on: 1 November 2010.</ref>
	~~<gallery>~~
	~~Image:Rheumatoid_nodule_-_low_mag.jpg \|Rheumatoid nodule - low mag. (WC)~~
	~~Image:Rheumatoid_nodule_-_intermed_mag_2.jpg \|Rheumatoid nodule - intermed. mag. (WC)~~
	~~Image:Rheumatoid_nodule_-_high_mag.jpg \|Rheumatoid nodule - high mag. (WC)~~
	~~</gallery>~~

	~~===Stains===~~
	*[[Alcian blue stain\|Alcian blue]] (pH 2.5) -ve.
	**Positive staining of mucin in [[granuloma annulare]].<ref name=pmid20523767>{{Cite journal \| last1 = Yun \| first1 = JH. \| last2 = Lee \| first2 = JY. \| last3 = Kim \| first3 = MK. \| last4 = Seo \| first4 = YJ. \| last5 = Kim \| first5 = MH. \| last6 = Cho \| first6 = KH. \| last7 = Kim \| first7 = MB. \| last8 = Lee \| first8 = WS. \| last9 = Lee \| first9 = KH. \| title = Clinical and pathological features of generalized granuloma annulare with their correlation: a retrospective multicenter study in Korea. \| journal = Ann Dermatol \| volume = 21 \| issue = 2 \| pages = 113-9 \| month = May \| year = 2009 \| doi = 10.5021/ad.2009.21.2.113 \| PMID = 20523767 \| PMC = 2861218 }}~~</ref>~~

	~~===Sign out===~~
	~~<pre>~~
	~~Lesion (subcutaneous), right index finger, excision:~~
	~~- Palisading granulomas with cores of necrobiotic collagen, consistent with rheumatoid nodule.~~
	~~</pre>~~

	~~====Micro====~~
	~~The sections show foci with strands of necrobiotic collagen surrounded by palisading granulomas. Rare Neutrophils are seen in the core of the granulomas. Multinucleated cells are not apparent.~~

	~~Benign fibroadipose tissue and dense connective tissue are also present.~~

	=Pleural disease=		=Pleural disease=

Michael at 16:57, 17 June 2014

2014-06-17T16:57:48Z

← Older revision		Revision as of 16:57, 17 June 2014
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	=External links=		=External links=
	*[http://www.pathguy.com/lectures/joints.htm Joint disease (pathguy.com)].		*[http://www.pathguy.com/lectures/joints.htm Joint disease (pathguy.com)].

	[[Category:Weird stuff]]		[[Category:Weird stuff]]
			[[Category:Diagnosis]]

Michael: /* Rheumatoid nodule */

2014-06-17T16:57:19Z

Rheumatoid nodule

← Older revision		Revision as of 16:57, 17 June 2014
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	Image:Rheumatoid_nodule_-_high_mag.jpg \|Rheumatoid nodule - high mag. (WC)		Image:Rheumatoid_nodule_-_high_mag.jpg \|Rheumatoid nodule - high mag. (WC)
	</gallery>		</gallery>

			===Stains===
			*[[Alcian blue stain\|Alcian blue]] (pH 2.5) -ve.
			**Positive staining of mucin in [[granuloma annulare]].<ref name=pmid20523767>{{Cite journal \| last1 = Yun \| first1 = JH. \| last2 = Lee \| first2 = JY. \| last3 = Kim \| first3 = MK. \| last4 = Seo \| first4 = YJ. \| last5 = Kim \| first5 = MH. \| last6 = Cho \| first6 = KH. \| last7 = Kim \| first7 = MB. \| last8 = Lee \| first8 = WS. \| last9 = Lee \| first9 = KH. \| title = Clinical and pathological features of generalized granuloma annulare with their correlation: a retrospective multicenter study in Korea. \| journal = Ann Dermatol \| volume = 21 \| issue = 2 \| pages = 113-9 \| month = May \| year = 2009 \| doi = 10.5021/ad.2009.21.2.113 \| PMID = 20523767 \| PMC = 2861218 }}</ref>

	===Sign out===		===Sign out===

Michael: /* Microscopic */

2014-04-22T17:50:28Z

Microscopic

← Older revision		Revision as of 17:50, 22 April 2014
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	*[http://library.med.utah.edu/WebPath/jpeg3/BONE044.jpg RA (med.utah.edu)].<ref>URL: [http://library.med.utah.edu/WebPath/EXAM/IMGQUIZ/msfrm.html http://library.med.utah.edu/WebPath/EXAM/IMGQUIZ/msfrm.html]. Accessed on: 5 December 2010.</ref>		*[http://library.med.utah.edu/WebPath/jpeg3/BONE044.jpg RA (med.utah.edu)].<ref>URL: [http://library.med.utah.edu/WebPath/EXAM/IMGQUIZ/msfrm.html http://library.med.utah.edu/WebPath/EXAM/IMGQUIZ/msfrm.html]. Accessed on: 5 December 2010.</ref>
	*[http://www.nature.com/nature/journal/v423/n6937/fig_tab/nature01661_F1.html Rheumatoid arthritis (nature.com)].		*[http://www.nature.com/nature/journal/v423/n6937/fig_tab/nature01661_F1.html Rheumatoid arthritis (nature.com)].
	*[http://www.medpath.info/MainContent/Skeletal/3100.GIF Synovial ~~hyperplasia and~~ inflammation (medpath.info)].<ref name=medpath/>		*[http://www.medpath.info/MainContent/Skeletal/3100.GIF Synovial inflammation (medpath.info)].<ref name=medpath/>
			*[http://www.medpath.info/MainContent/Skeletal/3109.GIF Hyperplastic synovitis (medpath.info)].<ref name=medpath/>
	*[http://ard.bmj.com/content/58/3.cover-expansion RA cartilage loss (bmj.com)].		*[http://ard.bmj.com/content/58/3.cover-expansion RA cartilage loss (bmj.com)].

Michael: /* Images */ more

2013-11-10T12:07:40Z

Images: more

← Older revision		Revision as of 12:07, 10 November 2013
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	<gallery>		<gallery>
	Image:Rheumatoid_nodule_-_low_mag.jpg \|Rheumatoid nodule - low mag. (WC)		Image:Rheumatoid_nodule_-_low_mag.jpg \|Rheumatoid nodule - low mag. (WC)
	**[http://commons.wikimedia.org/wiki/File:Rheumatoid_nodule_-_intermed_mag_2.jpg Rheumatoid nodule - intermed. mag. (WC)].		Image:Rheumatoid_nodule_-_intermed_mag_2.jpg \|Rheumatoid nodule - intermed. mag. (WC)
	**[http://commons.wikimedia.org/wiki/File:Rheumatoid_nodule_-_high_mag.jpg Rheumatoid nodule - high mag. (WC)].		Image:Rheumatoid_nodule_-_high_mag.jpg \|Rheumatoid nodule - high mag. (WC)
	</gallery>		</gallery>

Michael: /* Images */ x

2013-11-10T12:03:02Z

Images: x

← Older revision		Revision as of 12:03, 10 November 2013
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	===Images===		===Images===
	*www:		www:
	**[http://granuloma.homestead.com/rheumatoid_nod_S89-2617-1.jpg Rheumatoid nodule (granuloma.homestead.com)].<ref name=ghc>URL: [http://granuloma.homestead.com/palisading.html http://granuloma.homestead.com/palisading.html]. Accessed on: 1 November 2010.</ref>		*[http://granuloma.homestead.com/rheumatoid_nod_S89-2617-1.jpg Rheumatoid nodule (granuloma.homestead.com)].<ref name=ghc>URL: [http://granuloma.homestead.com/palisading.html http://granuloma.homestead.com/palisading.html]. Accessed on: 1 November 2010.</ref>
	**[http://granuloma.homestead.com/rheumatoid_nod_S89-2617-5.jpg Rheumatoid nodule (granuloma.homestead.com)].<ref name=ghc>URL: [http://granuloma.homestead.com/palisading.html http://granuloma.homestead.com/palisading.html]. Accessed on: 1 November 2010.</ref>		*[http://granuloma.homestead.com/rheumatoid_nod_S89-2617-5.jpg Rheumatoid nodule (granuloma.homestead.com)].<ref name=ghc>URL: [http://granuloma.homestead.com/palisading.html http://granuloma.homestead.com/palisading.html]. Accessed on: 1 November 2010.</ref>
	**[http://library.med.utah.edu/WebPath/jpeg3/BONE045.jpg Rheumatoid nodule (utah.edu)].<ref>URL: [http://www.pathguy.com/lectures/joints.htm http://www.pathguy.com/lectures/joints.htm]. Accessed on: 1 November 2010.</ref>		*[http://library.med.utah.edu/WebPath/jpeg3/BONE045.jpg Rheumatoid nodule (utah.edu)].<ref>URL: [http://www.pathguy.com/lectures/joints.htm http://www.pathguy.com/lectures/joints.htm]. Accessed on: 1 November 2010.</ref>
	<gallery>		<gallery>
	**[http://commons.wikimedia.org/wiki/File:Rheumatoid_nodule_-_low_mag.jpg Rheumatoid nodule - low mag. (WC)].		Image:Rheumatoid_nodule_-_low_mag.jpg \|Rheumatoid nodule - low mag. (WC)
	**[http://commons.wikimedia.org/wiki/File:Rheumatoid_nodule_-_intermed_mag_2.jpg Rheumatoid nodule - intermed. mag. (WC)].		**[http://commons.wikimedia.org/wiki/File:Rheumatoid_nodule_-_intermed_mag_2.jpg Rheumatoid nodule - intermed. mag. (WC)].
	**[http://commons.wikimedia.org/wiki/File:Rheumatoid_nodule_-_high_mag.jpg Rheumatoid nodule - high mag. (WC)].		**[http://commons.wikimedia.org/wiki/File:Rheumatoid_nodule_-_high_mag.jpg Rheumatoid nodule - high mag. (WC)].
	</gallery>		</gallery>

	===Sign out===		===Sign out===
	<pre>		<pre>