Rhabdomyoma - Revision history

Michael at 15:47, 22 April 2024

2024-04-22T15:47:58Z

← Older revision		Revision as of 15:47, 22 April 2024
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	*Vimentin -ve/+ve.		*Vimentin -ve/+ve.
	*S-100 -ve.		*S-100 -ve.
	**Positive in granular cell tumour and ~~hiberoma~~.		**Positive in granular cell tumour and hibernoma.

	==See also==		==See also==

Michael at 15:54, 4 September 2017

2017-09-04T15:54:50Z

← Older revision		Revision as of 15:54, 4 September 2017
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	{{ Infobox diagnosis		{{ Infobox diagnosis
	\| Name = {{PAGENAME}}		\| Name = {{PAGENAME}}
	\| Image =		\| Image = Rhabdomyoma -- high mag.jpg
	\| Width =		\| Width =
	\| Caption =		\| Caption = Rhabdomyoma. [[H&E stain]]. (WC)
	\| Synonyms =		\| Synonyms =
	\| Micro = spider cells (large polygonal cells (~10-20x RBC diameter), abundant cytoplasm with clearing)		\| Micro = spider cells (large polygonal cells (~10-20x RBC diameter), abundant cytoplasm with clearing)

Michael: +infobox

2017-09-04T15:53:52Z

+infobox

← Older revision		Revision as of 15:53, 4 September 2017
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			{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image =
			\| Width =
			\| Caption =
			\| Synonyms =
			\| Micro = spider cells (large polygonal cells (~10-20x RBC diameter), abundant cytoplasm with clearing)
			\| Subtypes = fetal rhabdomyoma, adult rhabdomyoma
			\| LMDDx = [[granular cell tumour]], [[hibernoma]], [[oncocytoma]]
			\| Stains =
			\| IHC = desmin +ve, actin +ve, myoglobin +ve, S-100 -ve
			\| EM =
			\| Molecular =
			\| IF =
			\| Gross =
			\| Grossing =
			\| Staging =
			\| Site = [[heart]] (see ''[[cardiac tumours]]), [[head and neck pathology\|head and neck]]
			\| Assdx =
			\| Syndromes =
			\| Clinicalhx =
			\| Signs =
			\| Symptoms =
			\| Prevalence = rare
			\| Bloodwork =
			\| Rads =
			\| Endoscopy =
			\| Prognosis = benign
			\| Other =
			\| ClinDDx =
			\| Tx =
			}}
	'''Rhabdomyoma''' a benign muscle tumour. Often seen in the context of [[tuberous sclerosis]].		'''Rhabdomyoma''' a benign muscle tumour. Often seen in the context of [[tuberous sclerosis]].

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	DDx:		DDx:
			*[[Hibernoma]].
			*[[Granular cell tumour]].
			*[[Oncocytoma]].
	*[[Lipoma]].		*[[Lipoma]].
	*[[Fat necrosis]].		*[[Fat necrosis]].
	*[[Hibernoma]].
	*[[Granular cell tumour]].

	===Images===		===Images===

Michael: /* See also */

2017-09-04T14:39:54Z

Michael: /* IHC */

2017-09-04T14:39:24Z

IHC

← Older revision		Revision as of 14:39, 4 September 2017
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	==IHC==		==IHC==
	Features:<ref name=pmid16133368 >{{Cite journal \| last1 = Hansen \| first1 = T. \| last2 = Katenkamp \| first2 = D. \| title = Rhabdomyoma of the head and neck: morphology and differential diagnosis. \| journal = Virchows Arch \| volume = 447 \| issue = 5 \| pages = 849-54 \| month = Nov \| year = 2005 \| doi = 10.1007/s00428-005-0038-8 \| PMID = 16133368 }}</ref>		Features:<ref name=pmid16133368 >{{Cite journal \| last1 = Hansen \| first1 = T. \| last2 = Katenkamp \| first2 = D. \| title = Rhabdomyoma of the head and neck: morphology and differential diagnosis. \| journal = Virchows Arch \| volume = 447 \| issue = 5 \| pages = 849-54 \| month = Nov \| year = 2005 \| doi = 10.1007/s00428-005-0038-8 \| PMID = 16133368 }}</ref>
	*Desmin +ve.		*Desmin +ve (21 of 21 adult cases<ref name=pmid8505039>{{Cite journal \| last1 = Kapadia \| first1 = SB. \| last2 = Meis \| first2 = JM. \| last3 = Frisman \| first3 = DM. \| last4 = Ellis \| first4 = GL. \| last5 = Heffner \| first5 = DK. \| last6 = Hyams \| first6 = VJ. \| title = Adult rhabdomyoma of the head and neck: a clinicopathologic and immunophenotypic study. \| journal = Hum Pathol \| volume = 24 \| issue = 6 \| pages = 608-17 \| month = Jun \| year = 1993 \| doi = \| PMID = 8505039 }}</ref>).
	*Myogoblin +ve.		*Myogoblin +ve.
	*Actin +ve.		*Actin +ve (21 of 21 adult cases<ref name=pmid8505039/>).
			*Vimentin -ve/+ve.
	*S-100 -ve.		*S-100 -ve.
	**Positive in granular cell tumour and hiberoma.		**Positive in granular cell tumour and hiberoma.

Michael: /* General */

2017-09-04T14:35:43Z

General

← Older revision		Revision as of 14:35, 4 September 2017
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	*May be seen in the context of [[tuberous sclerosis]].		*May be seen in the context of [[tuberous sclerosis]].
	*Rare benign mesenchymal tumour - may be seen in the [[head and neck pathology\|head and neck]].<ref name=pmid16133368/>		*Rare benign mesenchymal tumour - may be seen in the [[head and neck pathology\|head and neck]].<ref name=pmid16133368/>
			*Can cause death if in the [[cardiac tumours\|heart]].<ref name=pmid23206573 >{{Cite journal \| last1 = Neri \| first1 = M. \| last2 = Di Donato \| first2 = S. \| last3 = Maglietta \| first3 = R. \| last4 = Pomara \| first4 = C. \| last5 = Riezzo \| first5 = I. \| last6 = Turillazzi \| first6 = E. \| last7 = Fineschi \| first7 = V. \| title = Sudden death as presenting symptom caused by cardiac primary multicentric left ventricle rhabdomyoma, in an 11-month-old baby. An immunohistochemical study. \| journal = Diagn Pathol \| volume = 7 \| issue = \| pages = 169 \| month = Dec \| year = 2012 \| doi = 10.1186/1746-1596-7-169 \| PMID = 23206573 }}</ref>

	==Gross==		==Gross==

Michael: /* General */

2017-09-04T14:34:01Z

General

← Older revision		Revision as of 14:34, 4 September 2017
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	==General==		==General==
	*May be seen in the context of [[tuberous sclerosis]].		*May be seen in the context of [[tuberous sclerosis]].
			*Rare benign mesenchymal tumour - may be seen in the [[head and neck pathology\|head and neck]].<ref name=pmid16133368/>

	==Gross==		==Gross==

Michael: /* References */

2017-09-04T14:32:59Z

References

← Older revision		Revision as of 14:32, 4 September 2017
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	[[Category:Soft tissue lesions]]		[[Category:Soft tissue lesions]]
	[[Category:Diagnosis]]		[[Category:Diagnosis]]
			[[Category:Head and neck pathology]]

Michael: /* Microscopic */

2017-09-04T14:32:19Z

Microscopic

← Older revision		Revision as of 14:32, 4 September 2017
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	**Large polygonal cells (~10-20x RBC diameter):		**Large polygonal cells (~10-20x RBC diameter):
	***Abundant cytoplasm filled with glycogen.		***Abundant cytoplasm filled with glycogen.

			Note:
			*Fetal rhabdomyomas may have [[pseudoepitheliomatous hyperplasia]].<ref name=pmid16133368/>

	DDx:		DDx:

Michael: /* Microscopic */

2017-09-04T14:30:30Z

Microscopic

← Older revision		Revision as of 14:30, 4 September 2017
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	*[[Lipoma]].		*[[Lipoma]].
	*[[Fat necrosis]].		*[[Fat necrosis]].
	*[[~~Hiberoma~~]].		*[[Hibernoma]].
	*[[Granular cell tumour]].		*[[Granular cell tumour]].

← Older revision		Revision as of 14:39, 4 September 2017
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	==See also==		==See also==
	*[[Cardiac tumours]].		*[[Cardiac tumours]].
			*[[Head and neck pathology]].

	==References==		==References==