Retinoblastoma - Revision history

Michael at 03:55, 9 February 2016

2016-02-09T03:55:18Z

← Older revision		Revision as of 03:55, 9 February 2016
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	\| Caption = Retinoblastoma. (WC)		\| Caption = Retinoblastoma. (WC)
	\| Synonyms =		\| Synonyms =
	\| Micro = [[small round cell tumour]], Flexner-Wintersteiner [[rosette]]s		\| Micro = [[small round cell tumour]], Flexner-Wintersteiner [[rosette]]s, +/-Homer-Wright rosettes, mitoses (common), +/-necrosis, +/-calcifications
	\| Subtypes =		\| Subtypes =
	\| LMDDx = retinocytoma, other [[small round cell tumours]]		\| LMDDx = retinocytoma, other [[small round cell tumours]]
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	\| Tx =		\| Tx =
	}}		}}
	'''Retinoblastoma''' is malignant tumour the of the [[eye]].		'''Retinoblastoma''' is a malignant tumour the of the [[eye]].

	==General==		==General==

Michael at 03:53, 9 February 2016

2016-02-09T03:53:33Z

← Older revision		Revision as of 03:53, 9 February 2016
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	\| Caption = Retinoblastoma. (WC)		\| Caption = Retinoblastoma. (WC)
	\| Synonyms =		\| Synonyms =
	\| Micro = [[small round cell tumour]]		\| Micro = [[small round cell tumour]], Flexner-Wintersteiner [[rosette]]s
	\| Subtypes =		\| Subtypes =
	\| LMDDx =		\| LMDDx = retinocytoma, other [[small round cell tumours]]
	\| Stains =		\| Stains =
	\| IHC =		\| IHC =
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	\| Molecular =		\| Molecular =
	\| IF =		\| IF =
	\| Gross =		\| Gross = white, solid, friable
	\| Grossing =		\| Grossing =
	\| Staging =		\| Staging =

Michael: +image, +infobox

2016-02-09T03:52:06Z

+image, +infobox

← Older revision		Revision as of 03:52, 9 February 2016
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			{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image = Rtbl400.GIF
			\| Width =
			\| Caption = Retinoblastoma. (WC)
			\| Synonyms =
			\| Micro = [[small round cell tumour]]
			\| Subtypes =
			\| LMDDx =
			\| Stains =
			\| IHC =
			\| EM =
			\| Molecular =
			\| IF =
			\| Gross =
			\| Grossing =
			\| Staging =
			\| Site = [[eye]]
			\| Assdx =
			\| Syndromes =
			\| Clinicalhx =
			\| Signs =
			\| Symptoms =
			\| Prevalence = rare
			\| Bloodwork =
			\| Rads =
			\| Endoscopy =
			\| Prognosis =
			\| Other =
			\| ClinDDx =
			\| Tx =
			}}
	'''Retinoblastoma''' is malignant tumour the of the [[eye]].		'''Retinoblastoma''' is malignant tumour the of the [[eye]].

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	===Images===		===Images===
			<gallery>
			Image:Rtbl400.GIF \| Retinoblastoma. (WC)
			</gallery>
	====www====		====www====
	*[http://moon.ouhsc.edu/kfung/jty1/opaq/PathQuiz/O0A001-PQ01-M.htm Retinoblastoma (ouhsc.edu)].		*[http://moon.ouhsc.edu/kfung/jty1/opaq/PathQuiz/O0A001-PQ01-M.htm Retinoblastoma (ouhsc.edu)].

Michael: split out

2016-02-09T03:49:20Z

split out

← Older revision		Revision as of 03:49, 9 February 2016
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	~~#redirect~~ [[Eye~~#Retinoblastoma~~]]		'''Retinoblastoma''' is malignant tumour the of the [[eye]].

			==General==
			*Rare.
			*[[Malignant]].
			*May be familial.<ref name=pmid20687510>{{cite journal \|author=Lohmann D \|title=Retinoblastoma \|journal=Adv. Exp. Med. Biol. \|volume=685 \|issue= \|pages=220–7 \|year=2010 \|pmid=20687510 \|doi= \|url=}}</ref>

			==Gross==
			*White, solid.
			*Patterns:
			**Endophytic - grow into the vitreous cavity.
			**Exophytic - grow toward choroid.
			**Mixed - components of endophytic and exophytic.

			Note:
			*Tumour is extremely friable.

			===Image===
			*[http://radiopaedia.org/cases/retinoblastoma-gross-pathology Retinoblastoma (radiopaedia.org/AFIP)].

			==Microscopic==
			Features:
			*[[Small round cell tumour]]:
			**Scant cytoplasm.
			*Flexner-Wintersteiner [[rosette]] - '''key feature'''.
			**Rosette with empty centre (donut hole).<ref name=pmid16551982>{{cite journal \|author=Wippold FJ, Perry A \|title=Neuropathology for the neuroradiologist: rosettes and pseudorosettes \|journal=AJNR Am J Neuroradiol \|volume=27 \|issue=3 \|pages=488–92 \|year=2006 \|month=March \|pmid=16551982 \|doi= \|url=}}</ref>
			*+/-Homer-Wright rosette.<ref>WH. 14 March 2011.</ref>
			**Circular rosette with neuropil at the centre.<ref name=pmid16551982>{{cite journal \|author=Wippold FJ, Perry A \|title=Neuropathology for the neuroradiologist: rosettes and pseudorosettes \|journal=AJNR Am J Neuroradiol \|volume=27 \|issue=3 \|pages=488–92 \|year=2006 \|month=March \|pmid=16551982 \|doi= \|url=}}</ref>
			*Mitoses - common.
			*+/-Necrosis.
			*+/-Calcification.

			DDx:
			*Retinocytoma (retinoma) - benign counterpart of retinoblastoma.

			Notes:
			*DDx of Flexner-Wintersteiner rosette includes:
			**Pineoblastoma.
			**Medulloepithelioma.

			===Images===
			====www====
			*[http://moon.ouhsc.edu/kfung/jty1/opaq/PathQuiz/O0A001-PQ01-M.htm Retinoblastoma (ouhsc.edu)].
			*[http://www.pathpedia.com/Education/eAtlas/Histopathology/eye_and_ocular_adnexa/retinoblastoma.aspx Retinoblastoma (pathpedia.com)].

			==See also==
			*[[Eye]].
			*[[Small round cell tumours]].

			==References==
			{{Reflist\|1}}

	[[Category:Diagnosis]]		[[Category:Diagnosis]]
			[[Category:Eye]]

Michael: fix redirect

2012-03-27T20:14:22Z

fix redirect

← Older revision		Revision as of 20:14, 27 March 2012
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	#redirect [[Eye]]		#redirect [[Eye#Retinoblastoma]]

	[[Category:Diagnosis]]		[[Category:Diagnosis]]

Michael: +cat.

2011-10-18T03:29:35Z

+cat.

← Older revision		Revision as of 03:29, 18 October 2011
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	#redirect [[~~eye~~]]		#redirect [[Eye]]

			[[Category:Diagnosis]]

Michael: redirect for now

2010-10-19T19:28:18Z

redirect for now

New page

#redirect [[eye]]