Renal leiomyoma - Revision history

Michael at 19:52, 25 August 2015

2015-08-25T19:52:18Z

← Older revision		Revision as of 19:52, 25 August 2015
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	*Desmin +ve.		*Desmin +ve.
	*ER and PR +ve (6 of 9 cases:<ref name=pmid25517956/>).		*ER and PR +ve (6 of 9 cases:<ref name=pmid25517956/>).

			==Sign out==
			<pre>
			Mass Lesion, Right Kidney, Core Biopsy:
			- Benign leiomyoma with hyalinization and without atypia, see comment.
			- Renal parenchyma within normal limits present.
			- NEGATIVE for malignancy.

			Comment:
			The tumour stains as follows:
			POSITIVE: desmin, SMA, ER, PR.
			NEGATIVE: HMB-45.
			Proliferation (Ki-67): 0%.

			The tumour histology and immunoprofile is that of a leiomyoma. Renal leiomyomas are very rare lesions; a large contemporary series has only 9 cases. [1]

			Correlation with radiology is suggested.

			1. Am J Surg Pathol. 2015 Mar;39(3):349-56.
			</pre>

			===Micro===
			The sections show tumour with a fascicular architecture and hyalinization. No adipose tissue is seen. Necrosis is not identified. Nuclear atypia is not seen. Mitotic activity is not readily apparent. Benign unremarkable renal parenchyma is present.

	==See also==		==See also==

Michael: /* Microscopic */

2015-01-02T22:55:13Z

Microscopic

← Older revision		Revision as of 22:55, 2 January 2015
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	DDx:		DDx:
	*[[Angiomyolipoma]] - typically contain adipose tissue.		*[[Angiomyolipoma]] - typically contain adipose tissue.
			*[[Leiomyosarcoma]]<ref name=pmid25526990>{{Cite journal \| last1 = Fu \| first1 = L. \| last2 = Humphrey \| first2 = PA. \| last3 = Adeniran \| first3 = AJ. \| title = Renal Leiomyoma. \| journal = J Urol \| volume = \| issue = \| pages = \| month = Dec \| year = 2014 \| doi = 10.1016/j.juro.2014.12.083 \| PMID = 25526990 }}</ref> - typically have at least some of the following: nuclear atypia, mitosis, necrosis.

	==IHC==		==IHC==

Michael at 22:42, 2 January 2015

2015-01-02T22:42:04Z

← Older revision		Revision as of 22:42, 2 January 2015
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	'''Renal leiomyoma''', also '''leiomyoma of the [[kidney]], is a very rare benign [[kidney tumour]].		'''Renal leiomyoma''', also '''leiomyoma of the [[kidney]]''', is a very rare benign [[kidney tumour]].

	==General==		==General==
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	DDx:		DDx:
	*[[Angiomyolipoma]].		*[[Angiomyolipoma]] - typically contain adipose tissue.

	==IHC==		==IHC==
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	==See also==		==See also==
	*[[Leiomyoma]].		*[[Leiomyoma]].
			*[[Kidney tumours]].

	==References==		==References==

Michael: create

2015-01-02T22:40:46Z

create

New page

'''Renal leiomyoma''', also '''leiomyoma of the [[kidney]], is a very rare benign [[kidney tumour]].

==General==
*Rare - estimated to represent 0.3% of treated renal tumours.<ref>{{Cite journal | last1 = Khetrapal | first1 = S. | last2 = Bhargava | first2 = A. | last3 = Jetley | first3 = S. | last4 = Rana | first4 = S. | last5 = Jairajpuri | first5 = Z. | title = Renal leiomyoma: an uncommon differential diagnosis of renal masses with a clinical relevance. | journal = J Clin Diagn Res | volume = 8 | issue = 10 | pages = FD08-9 | month = Oct | year = 2014 | doi = 10.7860/JCDR/2014/9434.4993 | PMID = 25478354 }}</ref>

==Microscopic==
Features:
*Fasicular architecture.
*Spindle cells without significant atypia.

DDx:
*[[Angiomyolipoma]].

==IHC==
Features:<ref name=pmid25517956>{{Cite journal | last1 = Patil | first1 = PA. | last2 = McKenney | first2 = JK. | last3 = Trpkov | first3 = K. | last4 = Hes | first4 = O. | last5 = Montironi | first5 = R. | last6 = Scarpelli | first6 = M. | last7 = Nesi | first7 = G. | last8 = Aron | first8 = M. | last9 = Sangoi | first9 = AR. | title = Renal Leiomyoma: A Contemporary Multi-institution Study of an Infrequent and Frequently Misclassified Neoplasm. | journal = Am J Surg Pathol | volume = | issue = | pages = | month = Dec | year = 2014 | doi = 10.1097/PAS.0000000000000354 | PMID = 25517956 }}</ref>
*HMB-45 -ve.
*Desmin +ve.
*ER and PR +ve (6 of 9 cases:<ref name=pmid25517956/>).

==See also==
*[[Leiomyoma]].

==References==
{{Reflist|2}}

[[Category:Kidney tumours]]
[[Category:Diagnosis]]