Proliferative phase endometrium - Revision history

Michael: /* General */

2019-01-07T20:09:33Z

General

← Older revision		Revision as of 20:09, 7 January 2019
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	***On [[pap test]]s this is associated with the classic double contoured balls of endometrial epithelium and stroma.		***On [[pap test]]s this is associated with the classic double contoured balls of endometrial epithelium and stroma.
	*Proliferative activity is relatively common in postmenopausal women ~25% and probably associated with a small increased risk of malignancy.<ref name=pmid15280405>{{Cite journal \| last1 = Sivridis \| first1 = E. \| last2 = Giatromanolaki \| first2 = A. \| title = Proliferative activity in postmenopausal endometrium: the lurking potential for giving rise to an endometrial adenocarcinoma. \| journal = J Clin Pathol \| volume = 57 \| issue = 8 \| pages = 840-4 \| month = Aug \| year = 2004 \| doi = 10.1136/jcp.2003.014399 \| PMID = 15280405 }}</ref>		*Proliferative activity is relatively common in postmenopausal women ~25% and probably associated with a small increased risk of malignancy.<ref name=pmid15280405>{{Cite journal \| last1 = Sivridis \| first1 = E. \| last2 = Giatromanolaki \| first2 = A. \| title = Proliferative activity in postmenopausal endometrium: the lurking potential for giving rise to an endometrial adenocarcinoma. \| journal = J Clin Pathol \| volume = 57 \| issue = 8 \| pages = 840-4 \| month = Aug \| year = 2004 \| doi = 10.1136/jcp.2003.014399 \| PMID = 15280405 }}</ref>
	**~17% of asymptomatic postmenopausal women have proliferative endometrium.<ref name=pmid1872332>{{Cite journal \| last1 = Archer \| first1 = DF. \| last2 = McIntyre-Seltman \| first2 = K. \| last3 = Wilborn \| first3 = WW. \| last4 = Dowling \| first4 = EA. \| last5 = Cone \| first5 = F. \| last6 = Creasy \| first6 = GW. \| last7 = Kafrissen \| first7 = ME. \| title = Endometrial morphology in asymptomatic postmenopausal women. \| journal = Am J Obstet Gynecol \| volume = 165 \| issue = 2 \| pages = 317-20; discussion 320-2 \| month = Aug \| year = 1991 \| doi = \| PMID = 1872332 }}</ref>		**~17% of asymptomatic (unselected) postmenopausal women have proliferative endometrium.<ref name=pmid1872332>{{Cite journal \| last1 = Archer \| first1 = DF. \| last2 = McIntyre-Seltman \| first2 = K. \| last3 = Wilborn \| first3 = WW. \| last4 = Dowling \| first4 = EA. \| last5 = Cone \| first5 = F. \| last6 = Creasy \| first6 = GW. \| last7 = Kafrissen \| first7 = ME. \| title = Endometrial morphology in asymptomatic postmenopausal women. \| journal = Am J Obstet Gynecol \| volume = 165 \| issue = 2 \| pages = 317-20; discussion 320-2 \| month = Aug \| year = 1991 \| doi = \| PMID = 1872332 }}</ref>

	Note:		Note:

Michael: /* General */

2019-01-07T20:08:59Z

General

← Older revision		Revision as of 20:08, 7 January 2019
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	***On [[pap test]]s this is associated with the classic double contoured balls of endometrial epithelium and stroma.		***On [[pap test]]s this is associated with the classic double contoured balls of endometrial epithelium and stroma.
	*Proliferative activity is relatively common in postmenopausal women ~25% and probably associated with a small increased risk of malignancy.<ref name=pmid15280405>{{Cite journal \| last1 = Sivridis \| first1 = E. \| last2 = Giatromanolaki \| first2 = A. \| title = Proliferative activity in postmenopausal endometrium: the lurking potential for giving rise to an endometrial adenocarcinoma. \| journal = J Clin Pathol \| volume = 57 \| issue = 8 \| pages = 840-4 \| month = Aug \| year = 2004 \| doi = 10.1136/jcp.2003.014399 \| PMID = 15280405 }}</ref>		*Proliferative activity is relatively common in postmenopausal women ~25% and probably associated with a small increased risk of malignancy.<ref name=pmid15280405>{{Cite journal \| last1 = Sivridis \| first1 = E. \| last2 = Giatromanolaki \| first2 = A. \| title = Proliferative activity in postmenopausal endometrium: the lurking potential for giving rise to an endometrial adenocarcinoma. \| journal = J Clin Pathol \| volume = 57 \| issue = 8 \| pages = 840-4 \| month = Aug \| year = 2004 \| doi = 10.1136/jcp.2003.014399 \| PMID = 15280405 }}</ref>
			**~17% of asymptomatic postmenopausal women have proliferative endometrium.<ref name=pmid1872332>{{Cite journal \| last1 = Archer \| first1 = DF. \| last2 = McIntyre-Seltman \| first2 = K. \| last3 = Wilborn \| first3 = WW. \| last4 = Dowling \| first4 = EA. \| last5 = Cone \| first5 = F. \| last6 = Creasy \| first6 = GW. \| last7 = Kafrissen \| first7 = ME. \| title = Endometrial morphology in asymptomatic postmenopausal women. \| journal = Am J Obstet Gynecol \| volume = 165 \| issue = 2 \| pages = 317-20; discussion 320-2 \| month = Aug \| year = 1991 \| doi = \| PMID = 1872332 }}</ref>

	Note:		Note:

Michael: /* General */

2019-01-07T19:59:31Z

General

← Older revision		Revision as of 19:59, 7 January 2019
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	**"Exodus" pattern is a term used to describe exfoliation of endometrial cells during the proliferative phase.		**"Exodus" pattern is a term used to describe exfoliation of endometrial cells during the proliferative phase.
	***On [[pap test]]s this is associated with the classic double contoured balls of endometrial epithelium and stroma.		***On [[pap test]]s this is associated with the classic double contoured balls of endometrial epithelium and stroma.
	*Proliferative activity is relatively common in postmenopausal women ~25%.<ref name=pmid15280405>{{Cite journal \| last1 = Sivridis \| first1 = E. \| last2 = Giatromanolaki \| first2 = A. \| title = Proliferative activity in postmenopausal endometrium: the lurking potential for giving rise to an endometrial adenocarcinoma. \| journal = J Clin Pathol \| volume = 57 \| issue = 8 \| pages = 840-4 \| month = Aug \| year = 2004 \| doi = 10.1136/jcp.2003.014399 \| PMID = 15280405 }}</ref>		*Proliferative activity is relatively common in postmenopausal women ~25% and probably associated with a small increased risk of malignancy.<ref name=pmid15280405>{{Cite journal \| last1 = Sivridis \| first1 = E. \| last2 = Giatromanolaki \| first2 = A. \| title = Proliferative activity in postmenopausal endometrium: the lurking potential for giving rise to an endometrial adenocarcinoma. \| journal = J Clin Pathol \| volume = 57 \| issue = 8 \| pages = 840-4 \| month = Aug \| year = 2004 \| doi = 10.1136/jcp.2003.014399 \| PMID = 15280405 }}</ref>

	Note:		Note:

Michael: /* General */

2019-01-07T19:57:17Z

General

← Older revision		Revision as of 19:57, 7 January 2019
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	**"Exodus" pattern is a term used to describe exfoliation of endometrial cells during the proliferative phase.		**"Exodus" pattern is a term used to describe exfoliation of endometrial cells during the proliferative phase.
	***On [[pap test]]s this is associated with the classic double contoured balls of endometrial epithelium and stroma.		***On [[pap test]]s this is associated with the classic double contoured balls of endometrial epithelium and stroma.
			*Proliferative activity is relatively common in postmenopausal women ~25%.<ref name=pmid15280405>{{Cite journal \| last1 = Sivridis \| first1 = E. \| last2 = Giatromanolaki \| first2 = A. \| title = Proliferative activity in postmenopausal endometrium: the lurking potential for giving rise to an endometrial adenocarcinoma. \| journal = J Clin Pathol \| volume = 57 \| issue = 8 \| pages = 840-4 \| month = Aug \| year = 2004 \| doi = 10.1136/jcp.2003.014399 \| PMID = 15280405 }}</ref>

	Note:		Note:

Michael: /* Case 3 */

2017-03-02T19:16:03Z

Case 3

← Older revision		Revision as of 19:16, 2 March 2017
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	====Case 3====		====Case 3====
	<gallery>		<gallery>
	Image: Coiled endometrium -- low mag.jpg \| Coiled proliferative endometrium - low mag. (WC)		Image: Coiled endometrium -- low mag.jpg \| [[Coiled endometrium\|Coiled proliferative endometrium]] - low mag. (WC)
	Image: Coiled endometrium -- intermed mag.jpg \| Coiled proliferative endometrium - intermed. mag. (WC)		Image: Coiled endometrium -- intermed mag.jpg \| Coiled proliferative endometrium - intermed. mag. (WC)
	Image: Coiled endometrium - alt -- intermed mag.jpg \| Coiled proliferative endometrium - intermed. mag. (WC)		Image: Coiled endometrium - alt -- intermed mag.jpg \| Coiled proliferative endometrium - intermed. mag. (WC)
	Image: Coiled endometrium -- high mag.jpg \| Coiled proliferative endometrium - intermed. mag. (WC)		Image: Coiled endometrium -- high mag.jpg \| Coiled proliferative endometrium - intermed. mag. (WC)
	</gallery>		</gallery>

	====www====		====www====
	*[http://library.med.utah.edu/WebPath/FEMHTML/FEM017.html Proliferative phase endometrium (utah.edu)].		*[http://library.med.utah.edu/WebPath/FEMHTML/FEM017.html Proliferative phase endometrium (utah.edu)].

Michael: /* Images */ +images

2016-01-26T05:10:31Z

Images: +images

← Older revision		Revision as of 05:10, 26 January 2016
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	===Images===		===Images===
			====Case 1====
	<gallery>		<gallery>
	Image: Proliferative phase endometrium -- very low mag.jpg \| PPE - very low mag. (WC)		Image: Proliferative phase endometrium -- very low mag.jpg \| PPE - very low mag. (WC)
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	Image: Proliferative phase endometrium -- high mag.jpg \| PPE - high mag. (WC)		Image: Proliferative phase endometrium -- high mag.jpg \| PPE - high mag. (WC)
	</gallery>		</gallery>
			====Case 2====
	<gallery>		<gallery>
	Image:Endometrial epithelium with proliferation - intermed mag.jpg \| Proliferative endometrial epithelium - intermed. mag. (WC)		Image:Endometrial epithelium with proliferation - intermed mag.jpg \| Proliferative endometrial epithelium - intermed. mag. (WC)
	Image:Endometrial epithelium with proliferation - high mag.jpg \| Proliferative endometrial epithelium - high mag. (WC)		Image:Endometrial epithelium with proliferation - high mag.jpg \| Proliferative endometrial epithelium - high mag. (WC)
	</gallery>		</gallery>
	www:		====Case 3====
			<gallery>
			Image: Coiled endometrium -- low mag.jpg \| Coiled proliferative endometrium - low mag. (WC)
			Image: Coiled endometrium -- intermed mag.jpg \| Coiled proliferative endometrium - intermed. mag. (WC)
			Image: Coiled endometrium - alt -- intermed mag.jpg \| Coiled proliferative endometrium - intermed. mag. (WC)
			Image: Coiled endometrium -- high mag.jpg \| Coiled proliferative endometrium - intermed. mag. (WC)
			</gallery>
			====www====
	*[http://library.med.utah.edu/WebPath/FEMHTML/FEM017.html Proliferative phase endometrium (utah.edu)].		*[http://library.med.utah.edu/WebPath/FEMHTML/FEM017.html Proliferative phase endometrium (utah.edu)].
	*[http://www.cytochemistry.net/microanatomy/medical_lectures/028%20-%2019_16f.jpg Proliferative phase endometrium (cytochemistry.net)].<ref>URL: [http://www.cytochemistry.net/microanatomy/medical_lectures/oviduct_and_uterus.htm http://www.cytochemistry.net/microanatomy/medical_lectures/oviduct_and_uterus.htm]. Accessed on: 23 October 2012.</ref>		*[http://www.cytochemistry.net/microanatomy/medical_lectures/028%20-%2019_16f.jpg Proliferative phase endometrium (cytochemistry.net)].<ref>URL: [http://www.cytochemistry.net/microanatomy/medical_lectures/oviduct_and_uterus.htm http://www.cytochemistry.net/microanatomy/medical_lectures/oviduct_and_uterus.htm]. Accessed on: 23 October 2012.</ref>

Michael: /* Sign out */ .

2015-08-12T16:06:38Z

Sign out: .

← Older revision		Revision as of 16:06, 12 August 2015
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	==Sign out==		==Sign out==
			<pre>
			Endometrium, Curettage:
			- Proliferative endometrium.
			- Scant benign endocervical mucosa present.
			- NEGATIVE for hyperplasia and NEGATIVE for malignancy.
			</pre>

	<pre>		<pre>
	ENDOMETRIUM, BIOPSY:		ENDOMETRIUM, BIOPSY:

Michael: /* Microscopic */

2015-06-16T13:34:40Z

Microscopic

← Older revision		Revision as of 13:34, 16 June 2015
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	Notes:		Notes:
	* † McCluggage says one shouldn't call ''PPE'' without mitoses, as some pseudostratification can be seen in [[atrophic endometrium]].<ref name=pmid16873562>{{Cite journal \| last1 = McCluggage \| first1 = WG. \| title = My approach to the interpretation of endometrial biopsies and curettings. \| journal = J Clin Pathol \| volume = 59 \| issue = 8 \| pages = 801-12 \| month = Aug \| year = 2006 \| doi = 10.1136/jcp.2005.029702 \| PMID = 16873562 \| PMC = 1860448 }}</ref>		* † McCluggage says one shouldn't call ''PPE'' without mitoses, as some pseudostratification can be seen in [[atrophic endometrium]].<ref name=pmid16873562>{{Cite journal \| last1 = McCluggage \| first1 = WG. \| title = My approach to the interpretation of endometrial biopsies and curettings. \| journal = J Clin Pathol \| volume = 59 \| issue = 8 \| pages = 801-12 \| month = Aug \| year = 2006 \| doi = 10.1136/jcp.2005.029702 \| PMID = 16873562 \| PMC = 1860448 }}</ref>
	** There is no guidance on how hard one should look. ~~VL suggests searching~~ ~ 10 mm^2 with the 20x objective~~. This~~ represents approximately ~ 10 fields of view with a microscope that has a 22 mm eye piece.		** There is no guidance on how hard one should look. Perhaps ~ 10 mm<sup>2</sup> with the 20x objective? Ten millimetres squared represents approximately ~ 10 fields of view with a microscope that has a 22 mm eye piece.
	* Significant negatives:		* Significant negatives:
	** No vacuolation.		** No vacuolation.

Michael: /* Post-menopausal */

2014-02-05T17:37:50Z

Post-menopausal

← Older revision		Revision as of 17:37, 5 February 2014
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	- PROLIFERATIVE-TYPE ENDOMETRIUM, LIMITED STROMA PRESENT.		- PROLIFERATIVE-TYPE ENDOMETRIUM, LIMITED STROMA PRESENT.
	- STRIPPED ENDOCERVICAL EPITHELIUM WITHIN NORMAL LIMITS.		- STRIPPED ENDOCERVICAL EPITHELIUM WITHIN NORMAL LIMITS.
			- NO EVIDENCE OF HYPERPLASIA.
			</pre>

			====Mostly atrophic====
			<pre>
			ENDOMETRIUM, ASPIRATION:
			- FRAGMENTS OF PREDOMINANT INACTIVE, VERY WEAKLY PROLIFERATIVE ENDOMETRIAL EPITHELIUM
			ATTACHED TO A VERY SMALL AMOUNT OF UNREMARKABLE STROMA.
			- AMOUNT OF STROMA NOT SUFFICIENT TO ASSESS GLAND-TO-STROMA RATIO.
	- NO EVIDENCE OF HYPERPLASIA.		- NO EVIDENCE OF HYPERPLASIA.
	</pre>		</pre>

Michael: /* Micro */

2014-01-31T13:49:27Z

Micro

← Older revision		Revision as of 13:49, 31 January 2014
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	=====Compression artifact present=====		=====Compression artifact present=====
	The sections show endometrium with proliferative glands without significant dilation or irregularity of shape. An increased gland density is seen focally, at the edge of one tissue fragment, in association with tearing of the stroma (compression artifact). The gland-to-stroma ratio is otherwise within normal limits. Mitotic activity is present. No nuclear atypia is apparent. Benign endocervical epithelium is present.		The sections show endometrium with proliferative glands without significant dilation or irregularity of shape. An increased gland density is seen focally, at the edge of one tissue fragment, in association with tearing of the stroma (compression artifact). The gland-to-stroma ratio is otherwise within normal limits. Mitotic activity is present. No nuclear atypia is apparent. Benign endocervical epithelium is present.

			=====Minimal dilation and irregularity=====
			:''Used when it is a bit funny looking but '''not''' enough for [[disordered proliferative endometrium]]''.
			The sections show endometrium with proliferative glands. Rare mildly dilated glands (~2x surrounding) with minimal irregularity of shape are present. The gland-to-stroma ratio is within normal limits. Mitotic activity is present. No nuclear atypia is apparent.

	==See also==		==See also==