Pleomorphic lipoma - Revision history

Michael at 18:55, 1 March 2024

2024-03-01T18:55:30Z

← Older revision		Revision as of 18:55, 1 March 2024
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	*Ancient [[neurofibroma]].		*Ancient [[neurofibroma]].
	*Ancient [[schwannoma]].		*Ancient [[schwannoma]].

	~~===Images===~~
	*[http://www.webpathology.com/image.asp?case=435&n=1 Pleomorphic lipoma - low mag. (webpathology.com)].
	*[http://www.webpathology.com/image.asp?n=2&Case=435 Pleomorphic lipoma - high mag. (webpathology.com)].

	==IHC==		==IHC==

Michael: /* Microscopic */

2016-05-01T22:58:47Z

Microscopic

← Older revision		Revision as of 22:58, 1 May 2016
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	Notes:		Notes:
	*May overlap with ''[[spindle cell lipoma]]''.<ref name=spc_stanford>URL: [http://surgpathcriteria.stanford.edu/softfat/spindle_cell_lipoma/ http://surgpathcriteria.stanford.edu/softfat/spindle_cell_lipoma/]. Accessed on: 4 December 2010.</ref>		*May overlap with ''[[spindle cell lipoma]]''.<ref name=spc_stanford>URL: [http://surgpathcriteria.stanford.edu/softfat/spindle_cell_lipoma/
			http://surgpathcriteria.stanford.edu/softfat/spindle_cell_lipoma/]. Accessed on: 4 December 2010.</ref>
	*Floret cell - may look similar to [[Touton giant cell]]s.		*Floret cell - may look similar to [[Touton giant cell]]s.

	~~Images:~~
	*[http://www.webpathology.com/image.asp?case=435&n=1 Pleomorphic lipoma - low mag. (webpathology.com)].
	*[http://www.webpathology.com/image.asp?n=2&Case=435 Pleomorphic lipoma - high mag. (webpathology.com)].

	DDx:		DDx:
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	*Ancient [[neurofibroma]].		*Ancient [[neurofibroma]].
	*Ancient [[schwannoma]].		*Ancient [[schwannoma]].

			===Images===
			*[http://www.webpathology.com/image.asp?case=435&n=1 Pleomorphic lipoma - low mag. (webpathology.com)].
			*[http://www.webpathology.com/image.asp?n=2&Case=435 Pleomorphic lipoma - high mag. (webpathology.com)].

	==IHC==		==IHC==

Michael at 22:58, 1 May 2016

2016-05-01T22:58:22Z

← Older revision		Revision as of 22:58, 1 May 2016
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	'''~~Pleomorphic_lipoma~~''' is a rare [[Adipocytic tumours\|adipocytic tumour]].		'''Pleomorphic lipoma''' is a rare [[Adipocytic tumours\|adipocytic tumour]].

	==General==		==General==
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	==See also==		==See also==
	*[[Adipocytic tumours]].		*[[Adipocytic tumours]].
			*[[Spindle cell lipoma]].

	==References==		==References==

Michael: split out

2016-05-01T22:58:04Z

split out

← Older revision		Revision as of 22:58, 1 May 2016
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	~~#redirect~~ [[~~Adipocytic_tumours#Pleomorphic_lipoma~~]]		'''Pleomorphic_lipoma''' is a rare [[Adipocytic tumours\|adipocytic tumour]].

			==General==
			*Rare.
			*May mimic a malignancy.<ref name=pmid15510605>{{Cite journal \| last1 = Persichetti \| first1 = P. \| last2 = Di Lella \| first2 = F. \| last3 = Marangi \| first3 = GF. \| last4 = Cagli \| first4 = B. \| last5 = Simone \| first5 = P. \| last6 = Tenna \| first6 = S. \| last7 = Rabitri \| first7 = C. \| last8 = Cassandro \| first8 = R. \| last9 = Esposito \| first9 = V. \| title = Pleomorphic lipoma: a definite histopathological entity. \| journal = Anticancer Res \| volume = 24 \| issue = 5B \| pages = 3157-9 \| month = \| year = \| doi = \| PMID = 15510605 }}</ref>
			*Male > female.<ref name=pmid18181679>{{Cite journal \| last1 = Syed \| first1 = S. \| last2 = Martin \| first2 = AM. \| last3 = Haupt \| first3 = H. \| last4 = Podolski \| first4 = V. \| last5 = Brooks \| first5 = JJ. \| title = Frequent detection of androgen receptors in spindle cell lipomas: an explanation for this lesion's male predominance? \| journal = Arch Pathol Lab Med \| volume = 132 \| issue = 1 \| pages = 81-3 \| month = Jan \| year = 2008 \| doi = 10.1043/1543-2165(2008)132[81:FDOARI]2.0.CO;2 \| PMID = 18181679 }}</ref>

			==Gross==
			*Classically shoulder and neck region in adults.<ref>URL: [http://www.webpathology.com/image.asp?n=2&Case=435 http://www.webpathology.com/image.asp?n=2&Case=435]. Accessed on: 3 October 2011.</ref>

			DDx - shoulder lesions:
			*[[Elastofibroma]].
			*[[Desmoplastic fibroblastoma]].

			==Microscopic==
			Features:
			*Multinucleated cells - "floret cells" - '''key feature'''.
			**Solid eosinophilic cytoplasm.
			**Peripheral nuclei - impart a knobby border to the cells.
			*Fibrous septa.

			Notes:
			*May overlap with ''[[spindle cell lipoma]]''.<ref name=spc_stanford>URL: [http://surgpathcriteria.stanford.edu/softfat/spindle_cell_lipoma/ http://surgpathcriteria.stanford.edu/softfat/spindle_cell_lipoma/]. Accessed on: 4 December 2010.</ref>
			*Floret cell - may look similar to [[Touton giant cell]]s.

			Images:
			*[http://www.webpathology.com/image.asp?case=435&n=1 Pleomorphic lipoma - low mag. (webpathology.com)].
			*[http://www.webpathology.com/image.asp?n=2&Case=435 Pleomorphic lipoma - high mag. (webpathology.com)].

			DDx:
			*[[Liposarcoma]].<ref name=pmid6884998>{{Cite journal \| last1 = Azzopardi \| first1 = JG. \| last2 = Iocco \| first2 = J. \| last3 = Salm \| first3 = R. \| title = Pleomorphic lipoma: a tumour simulating liposarcoma. \| journal = Histopathology \| volume = 7 \| issue = 4 \| pages = 511-23 \| month = Jul \| year = 1983 \| doi = \| PMID = 6884998 }}</ref>
			*Ancient [[neurofibroma]].
			*Ancient [[schwannoma]].

			==IHC==
			*AR +ve - ~95% in men, ~85% in women.<ref name=pmid18181679>{{Cite journal \| last1 = Syed \| first1 = S. \| last2 = Martin \| first2 = AM. \| last3 = Haupt \| first3 = H. \| last4 = Podolski \| first4 = V. \| last5 = Brooks \| first5 = JJ. \| title = Frequent detection of androgen receptors in spindle cell lipomas: an explanation for this lesion's male predominance? \| journal = Arch Pathol Lab Med \| volume = 132 \| issue = 1 \| pages = 81-3 \| month = Jan \| year = 2008 \| doi = 10.1043/1543-2165(2008)132[81:FDOARI]2.0.CO;2 \| PMID = 18181679 }}</ref>
			*CD34 +ve (26 +ve of 26 cases<ref name=pmid25219904>{{Cite journal \| last1 = Cheah \| first1 = A. \| last2 = Billings \| first2 = S. \| last3 = Goldblum \| first3 = J. \| last4 = Hornick \| first4 = J. \| last5 = Uddin \| first5 = N. \| last6 = Rubin \| first6 = B. \| title = Spindle cell/pleomorphic lipomas of the face: an under-recognized diagnosis. \| journal = Histopathology \| volume = 66 \| issue = 3 \| pages = 430-7 \| month = Feb \| year = 2015 \| doi = 10.1111/his.12548 \| PMID = 25219904 }}</ref>).
			*Desmin -ve (0 +ve of 20 cases<ref name=pmid25219904/>).
			*ER -ve/+ve (5 +ve of 21 cases<ref name=pmid25219904/>).

			==See also==
			*[[Adipocytic tumours]].

			==References==
			{{Reflist\|2}}

	[[Category:Diagnosis]]		[[Category:Diagnosis]]
			[[Category:Adipocytic tumours]]

Michael: redirect

2011-10-20T04:50:21Z

redirect

← Older revision		Revision as of 04:50, 20 October 2011
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	#redirect [[Adipocytic_tumours#Pleomorphic_lipoma]]		#redirect [[Adipocytic_tumours#Pleomorphic_lipoma]]

			[[Category:Diagnosis]]

Michael: redirect to pleomorphic lipoma

2011-10-04T01:54:50Z

redirect to pleomorphic lipoma

New page

#redirect [[Adipocytic_tumours#Pleomorphic_lipoma]]